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Laurent Gauthier

Laurent Gauthier

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
12003
World Ranking
17491
National Ranking
751

Overview

Laurent Gauthier is affiliated with Innate Pharma in France. Their research spans multiple fields, primarily within Medicine and Biochemistry, Genetics and Molecular Biology. The scientist's work extensively covers subfields such as Molecular Biology, Immunology, Genetics, Oncology, and Insect Science.

The topics frequently addressed in their research include:

  • Immune Cell Function and Interaction
  • CAR-T Cell Therapy Research
  • DNA Repair Mechanisms
  • Glioma Diagnosis and Treatment
  • Insect and Pesticide Research
  • Insect and Arachnid Ecology and Behavior
  • Plant and Animal Studies

L. Gauthier has contributed to several scientific publications across multiple venues. Notable recent papers include:

  • "Putative determinants of virulence in Melissococcus plutonius, the bacterial agent causing European foulbrood in honey bees" (2020, Virulence)
  • "Increase in lamin B1 promotes telomere instability by disrupting the shelterin complex in human cells" (2021, Nucleic Acids Research)
  • "Population genetic diversity and dynamics of the honey bee brood pathogen Melissococcus plutonius in a region with high prevalence" (2022, Journal of Invertebrate Pathology)
  • "The HIF1α/JMY pathway promotes glioblastoma stem-like cell invasiveness after irradiation" (2020, Scientific Reports)
  • "IPH6501 Is a Novel NKp46-Targeting Tetraspecific Antibody-Based Natural Killer Cell Engager Therapeutic (ANKET) Armed with a Non-Alpha IL-2 Variant and Developed for the Treatment of CD20-Positive Malignancies" (2022, Blood)

Frequent publication venues for this researcher include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Virulence
  • Nucleic Acids Research
  • Journal of Invertebrate Pathology

Collaborations are an integral part of Laurent Gauthier's research profile. Frequent co-authors include:

  • François D. Boussin
  • Éric Vivier
  • Christine Granotier
  • Yannis Morel
  • Benjamín Rossi

Best Publications

  • Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along Microtubules

    Laurent R Gauthier;Bénédicte C Charrin;Maria Borrell-Pagès;Jim P Dompierre

  • Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells

    Pascale André;Caroline Denis;Caroline Soulas;Clarisse Bourbon-Caillet

  • Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46

    Thierry Walzer;Mathieu Bléry;Julie Chaix;Nicolas Fuseri

  • Recognition of peptide–MHC class I complexes by activating killer immunoglobulin-like receptors

    C. Andrew Stewart;Fanny Laugier-Anfossi;Frédéric Vély;Xavier Saulquin

  • Preclinical characterization of 1-7F9, a novel human anti–KIR receptor therapeutic antibody that augments natural killer–mediated killing of tumor cells

    Francois Romagné;Pascale André;Pieter Spee;Stefan Zahn

  • Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein

    Kathrine J. Smith;Jason Pyrdol;Laurent Gauthier;Don C. Wiley

  • Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies.

    Ivan Perrot;Henri-Alexandre Michaud;Marc Giraudon-Paoli;Séverine Augier

  • Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering

    Laurent Gauthier;Benjamin Rossi;Florence Roux;Elise Termine

  • Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers

    Cheryl L. Day;Nilufer P. Seth;Michaela Lucas;Heiner Appel

  • Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity.

    Laurent Gauthier;Ariane Morel;Nadia Anceriz;Benjamin Rossi

  • Preferential binding of a G-quadruplex ligand to human chromosome ends

    Christine Granotier;Gaëlle Pennarun;Lydia Riou;Françoise Hoffschir

  • Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

    Christian Boehler;Laurent R. Gauthier;Oliver Mortusewicz;Denis S. Biard

  • Transglutaminase-Based Chemo-Enzymatic Conjugation Approach Yields Homogeneous Antibody–Drug Conjugates

    Patrick Dennler;Aristeidis Chiotellis;Eliane Fischer;Delphine Brégeon

  • Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands.

    Gaëlle Pennarun;Christine Granotier;Laurent R Gauthier;Dennis Gomez

  • AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51.

    Isabelle Plo;Corentin Laulier;Laurent Gauthier;Fabienne Lebrun

  • Radiation-induced mitotic catastrophe in PARG-deficient cells.

    Jean-Christophe Amé;Elise Fouquerel;Laurent R. Gauthier;Denis Biard

  • Recombinant soluble human alpha 3 beta 1 integrin: purification, processing, regulation, and specific binding to laminin-5 and invasin in a mutually exclusive manner.

    Johannes A. Eble;Kai W. Wucherpfennig;Laurent Gauthier;Petra Dersch

  • TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA

    Ivan Perrot;Florence Deauvieau;Catherine Massacrier;Nicola Hughes

  • Molecular detection of telomerase-positive circulating epithelial cells in metastatic breast cancer patients.

    Jean-Charles Soria;Laurent R. Gauthier;Eric Raymond;Christine Granotier

  • Mechanisms that generate human immunoglobulin diversity operate from the 8th week of gestation in fetal liver

    Anne‐Marie Cuisinier;Laurent Gauthier;Léon Boubli;Michel Fougereau

Frequent Co-Authors

Alessandro Moretta
Alessandro Moretta University of Genoa
Eric Vivier
Eric Vivier Aix-Marseille University
Kai W. Wucherpfennig
Kai W. Wucherpfennig Harvard University
Armand Bensussan
Armand Bensussan Hôpital Saint-Louis
Roger Schibli
Roger Schibli ETH Zurich
Valérie Schreiber
Valérie Schreiber Institute of Genetics and Molecular and Cellular Biology
Françoise Dantzer
Françoise Dantzer University of Strasbourg
Erwan Morellec
Erwan Morellec École Polytechnique Fédérale de Lausanne
Hervé Chneiweiss
Hervé Chneiweiss Université Paris Cité
Martial Ruat
Martial Ruat Centre national de la recherche scientifique, CNRS

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