World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
72
Citations
22200
World Ranking
6196
National Ranking
2914

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Joel A. Swanson is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple disciplines including biochemistry, genetics and molecular biology, immunology and microbiology, and medicine. Within these fields, they have contributed notably to subfields such as cell biology, immunology, physiology, molecular biology, and epidemiology.

The primary topics addressed in their work include cellular transport and secretion, erythrocyte function and pathophysiology, immune cells in cancer, immune cell function and interaction, cellular mechanics and interactions, HIV research and treatment, and calcium signaling and nucleotide metabolism.

Swanson's recent publications encompass diverse aspects of cellular and molecular biology. Notable papers include:

  • "Parkinson's disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes," 2022, Cell
  • "Macropinocytosis drives T cell growth by sustaining the activation of mTORC1," 2020, Nature Communications
  • "The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy," 2021, Nature Communications
  • "Alveolar macrophage-derived extracellular vesicles inhibit endosomal fusion of influenza virus," 2020, The EMBO Journal
  • "Roles for 3' Phosphoinositides in Macropinocytosis," 2022, Sub-cellular biochemistry/Subcellular biochemistry

Their frequent coauthors include Natalie W. Thiex, Adam D. Hoppe, Matangi Marthi, Philip D. King, and Shayne E. Quinn, with collaborations occurring multiple times across projects.

Swanson's research has been published in a range of venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Cell Science
  • Cell
  • Sub-cellular biochemistry/Subcellular biochemistry

In recognition of their contributions to science, Swanson was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

  • Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities

    Go Saito;Joel A. Swanson;Kyung Dall Lee

  • A Role for Phosphoinositide 3-Kinase in the Completion of Macropinocytosis and Phagocytosis by Macrophages

    Nobukazu Araki;Melissa T. Johnson;Joel A. Swanson

  • Shaping cups into phagosomes and macropinosomes

    Joel A. Swanson

  • pH-dependent regulation of lysosomal calcium in macrophages.

    Kenneth A. Christensen;Jesse T. Myers;Joel A. Swanson

  • Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes.

    C M Alpuche Aranda;J A Swanson;W P Loomis;S I Miller

  • ATP4- permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes.

    T H Steinberg;A S Newman;J A Swanson;S C Silverstein

  • Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

    Leif E. Sander;Michael J. Davis;Mark V. Boekschoten;Derk Amsen

  • Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes.

    C M Alpuche-Aranda;E L Racoosin;J A Swanson;S I Miller

  • Phagocytosis by zippers and triggers.

    Joel A. Swanson;Stephen C. Baer

  • Cdc42, Rac1, and Rac2 Display Distinct Patterns of Activation during Phagocytosis

    Adam D. Hoppe;Joel A. Swanson

  • The coordination of signaling during Fc receptor-mediated phagocytosis

    Joel A. Swanson;Adam D. Hoppe

  • Fluorescence resonance energy transfer-based stoichiometry in living cells.

    Adam Hoppe;Kenneth Christensen;Joel A. Swanson

  • Macropinosome maturation and fusion with tubular lysosomes in macrophages.

    E L Racoosin;J A Swanson

  • Phorbol esters and horseradish peroxidase stimulate pinocytosis and redirect the flow of pinocytosed fluid in macrophages.

    Joel A. Swanson;Brian D. Yirinec;Samuel C. Silverstein

  • The endocytic activity of dendritic cells.

    Ralph M. Steinman;Joel Swanson

  • A contractile activity that closes phagosomes in macrophages

    Joel A. Swanson;Melissa T. Johnson;Karen Beningo;Penny Post

  • The macrophage capacity for phagocytosis.

    G.J. Cannon;J.A. Swanson

  • The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells

    Ian J. Glomski;Margaret M. Gedde;Albert W. Tsang;Joel A. Swanson

  • Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules

    Joel Swanson;Anne Bushnell;Samuel C. Silverstein

  • pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.

    Kathryn E. Beauregard;Kyung Dall Lee;R. John Collier;Joel A. Swanson

Frequent Co-Authors

Samuel C. Silverstein
Samuel C. Silverstein Columbia University
Thomas H. Steinberg
Thomas H. Steinberg Washington University in St. Louis
D L Taylor
D L Taylor University of Pittsburgh
Marc Peters-Golden
Marc Peters-Golden University of Michigan–Ann Arbor
Yu-Kyoung Oh
Yu-Kyoung Oh Seoul National University
Mark V. Boekschoten
Mark V. Boekschoten Wageningen University & Research
Sofia D. Merajver
Sofia D. Merajver University of Michigan–Ann Arbor
Elizabeth J. Luna
Elizabeth J. Luna University of Massachusetts Chan Medical School
Michael Müller
Michael Müller University of East Anglia
Daniel A. Portnoy
Daniel A. Portnoy University of California, Berkeley

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