World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
32503
World Ranking
2529
National Ranking
1330

Overview

Jan M. Orenstein is affiliated with George Washington University in the United States. Their research primarily falls within the field of Medicine, with notable subfields including Rheumatology, Epidemiology, and Surgery.

The scientist's recent publications cover a variety of topics related to human health and pathology. Key papers include:

  • An ultrastructural pathologist's views on fibroblasts, modified smooth muscle cells, wound healing, stenosing arteriopathies, Kawasaki disease, Dupuytren's contracture, and the stroma of carcinomas (2020, Ultrastructural Pathology)
  • Human airway epithelial cell culture to identify new respiratory viruses: Coronavirus NL63 as a model (2021, UNC Libraries)
  • Human airway epithelial cell culture to identify new respiratory viruses: Coronavirus NL63 as a model (2020, UNC Libraries)

The scientist's research topics span multiple areas, highlighting a focus on both respiratory and connective tissue conditions. These include:

  • Respiratory viral infections research
  • Dupuytren's Contracture and Treatments
  • Soft tissue tumor case studies
  • Genital Health and Disease

Jan M. Orenstein has contributed to publications frequently appearing in the venues UNC Libraries and Ultrastructural Pathology.

Collaboration is present in their research, with frequent co-authors comprising:

  • Bridget S. Banach
  • Linda M. Fox
  • Scott H. Randell
  • Anne H. Rowley
  • Susan Baker

The scientist's work includes detailed pathological studies such as those addressing the cellular and ultrastructural aspects of various diseases. Their investigation into respiratory viruses makes use of airway epithelial cell culture models, emphasizing viral identification and mechanisms.

Overall, Jan M. Orenstein's scholarly output reflects interdisciplinary research across pathology, epidemiology, and clinical medicine, focusing on both viral infectious diseases and connective tissue disorders.

Best Publications

  • Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy.

    Scott Koenig;Howard E. Gendelman;Jan M. Orenstein;Mauro Carlo Dal Canto

  • Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

    Lesley E. Smythies;Marty Sellers;Ronald H. Clements;Meg Mosteller-Barnum

  • The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release.

    T Klimkait;K Strebel;M D Hoggan;M A Martin

  • p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing protease.

    Mingjun Huang;J. M. Orenstein;M. A. Martin;E. O. Freed

  • Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication.

    A Engelman;G Englund;J M Orenstein;M A Martin

  • Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function

    Dimiter G. Demirov;Akira Ono;Jan M. Orenstein;Eric O. Freed

  • The macrophage in the persistence and pathogenesis of HIV infection

    H. E. Gendelman;J. M. Orenstein;L. M. Baca;Barbara Weiser

  • Intestinal Macrophages Lack CD14 and CD89 and Consequently Are Down-Regulated for LPS- and IgA-Mediated Activities

    Phillip D. Smith;Lesley E. Smythies;Meg Mosteller-Barnum;Don A. Sibley

  • Human immunodeficiency virus impairs reverse cholesterol transport from macrophages.

    Zahedi A Mujawar;Honor May Rose;Matthew P Morrow;Tatiana Pushkarsky

  • Processing tissue and cells for transmission electron microscopy in diagnostic pathology and research

    Lesley Graham;Jan Marc Orenstein

  • Single amino acid changes in the human immunodeficiency virus type 1 matrix protein block virus particle production.

    E O Freed;J M Orenstein;A J Buckler-White;M A Martin

  • Three Linked Vasculopathic Processes Characterize Kawasaki Disease: A Light and Transmission Electron Microscopic Study

    Jan Marc Orenstein;Stanford T. Shulman;Linda M. Fox;Susan C. Baker

  • High-level variability in the ORF-K1 membrane protein gene at the left end of the Kaposi's sarcoma-associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populations.

    Jian Chao Zong;Dolores M. Ciufo;Donald J. Alcendor;Xiaoyu Wan

  • Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells.

    Gang Meng;Xiping Wei;Xiaoyun Wu;Marty T. Sellers

  • Role of the Gag Matrix Domain in Targeting Human Immunodeficiency Virus Type 1 Assembly

    Akira Ono;Jan M. Orenstein;Eric O. Freed

  • Isolation and Characterization of a New Human Microsporidian, Encephalitozoon hellem (n. sp.), from Three AIDS Patients with Keratoconjunctivitis

    E. S. Didier;P. J. Didier;D. N. Friedberg;S. M. Stenson

  • Cytoplasmic assembly and accumulation of human immunodeficiency virus types 1 and 2 in recombinant human colony-stimulating factor-1-treated human monocytes: an ultrastructural study.

    Jan Marc Orenstein;Monte S. Meltzer;Terri Phipps;Howard Gendelman

  • Comparison of Genetic Variability at Multiple Loci across the Genomes of the Major Subtypes of Kaposi’s Sarcoma-Associated Herpesvirus Reveals Evidence for Recombination and for Two Distinct Types of Open Reading Frame K15 Alleles at the Right-Hand End

    Lynn J. Poole;Jian Chao Zong;Dolores M. Ciufo;Donald J. Alcendor

  • The Late Domain of Human Immunodeficiency Virus Type 1 p6 Promotes Virus Release in a Cell Type-Dependent Manner

    Dimiter G. Demirov;Jan M. Orenstein;Eric O. Freed

  • R5 HIV productively infects langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms

    Tatsuyoshi Kawamura;Forrest O. Gulden;Makoto Sugaya;David T. McNamara

Frequent Co-Authors

Elizabeth S. Didier
Elizabeth S. Didier Tulane University
Howard E. Gendelman
Howard E. Gendelman University of Nebraska Medical Center
Eric O. Freed
Eric O. Freed National Institutes of Health
Monte S. Meltzer
Monte S. Meltzer Walter Reed Army Institute of Research
Phillip D. Smith
Phillip D. Smith University of Alabama at Birmingham
Sharon M. Wahl
Sharon M. Wahl National Institutes of Health
Matthias J. Schnell
Matthias J. Schnell Thomas Jefferson University
Donald P. Kotler
Donald P. Kotler Mount Sinai Morningside
Douglas T. Dieterich
Douglas T. Dieterich Icahn School of Medicine at Mount Sinai
Malcolm A. Martin
Malcolm A. Martin National Institutes of Health

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