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D-Index & Metrics

Medicine

D-Index
73
Citations
26045
World Ranking
19553
National Ranking
108

Research.com Recognitions

  • 2003 - Member of the European Academy of Sciences
  • 1998 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Pathology and Forensic Medicine
  • Member of the European Academy of Sciences and Arts
  • Member of the European Academy of Sciences and Arts

Overview

Helmut Denk is affiliated with the Medical University of Graz in Austria. Their research primarily focuses on medicine with additional contributions in biochemistry, genetics, and molecular biology. Their work spans several subfields, including epidemiology, cell biology, endocrinology, diabetes and metabolism, surgery, and pathology and forensic medicine.

Their main topics of study encompass liver disease diagnosis and treatment, endoplasmic reticulum stress and disease, alcohol consumption and health effects, pancreatic function and diabetes, diet, metabolism and disease, genetic and kidney cyst diseases, and peptidase inhibition and analysis.

Recent publications by Helmut Denk include:

  • Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi∗Z Variant of AAT (Pi∗MZ vs Pi∗ZZ genotype) and Noncarriers, 2020, Gastroenterology
  • From the origin of NASH to the future of metabolic fatty liver disease, 2021, Gut
  • Development and prognostic relevance of a histologic grading and staging system for alcohol-related liver disease, 2021, Journal of Hepatology
  • Different Roles of p62 (SQSTM1) Isoforms in Keratin-Related Protein Aggregation, 2021, International Journal of Molecular Sciences
  • Alpha-1 Antitrypsin Augmentation and the Liver Phenotype of Adults With Alpha-1 Antitrypsin Deficiency (Genotype Pi∗ZZ), 2023, Clinical Gastroenterology and Hepatology

Frequent co-authors include:

  • Aleksander Krag
  • Kurt Zatloukal
  • Mattias Mandorfer
  • Pavel Strnad
  • Matthias Reichert

Helmut Denk has published extensively in the following venues:

  • Journal of Hepatology
  • Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  • Zeitschrift für Gastroenterologie
  • International Journal of Molecular Sciences
  • Gastroenterology

Their research has been recognized by memberships and awards, including being a member of the European Academy of Sciences since 2003 and membership in the German National Academy of Sciences Leopoldina, with acknowledgment in pathology and forensic medicine. They are also a member of the European Academy of Sciences and Arts.

Best Publications

  • Histological grading and staging of chronic hepatitis.

    Kamal Ishak;Amelia Baptista;Leonardo Bianchi;Francesco Callea

  • Causability and explainability of artificial intelligence in medicine.

    Andreas Holzinger;Georg Langs;Helmut Denk;Kurt Zatloukal

  • Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.

    Katrin Panzitt;Marisa M.O. Tschernatsch;Christian Guelly;Tarek Moustafa

  • p62 Is a Common Component of Cytoplasmic Inclusions in Protein Aggregation Diseases

    Kurt Zatloukal;Cornelia Stumptner;Andrea Fuchsbichler;Hans Heid

  • Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

    Peter Fickert;Andrea Fuchsbichler;Martin Wagner;Gernot Zollner

  • CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice

    Martin Wagner;Emina Halilbasic;Hanns-Ulrich Marschall;Gernot Zollner

  • A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.

    Peter Fickert;Ulrike Stöger;Andrea Fuchsbichler;Tarek Moustafa

  • Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis

    Gernot Zollner;Peter Fickert;Dagmar Silbert;Andrea Fuchsbichler

  • Effects of Ursodeoxycholic and Cholic Acid Feeding on Hepatocellular Transporter Expression in Mouse Liver

    Peter Fickert;Gernot Zollner;Andrea Fuchsbichler;Conny Stumptner

  • Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles.

    Peter Fickert;Gernot Zollner;Andrea Fuchsbichler;Conny Stumptner

  • 24-norUrsodeoxycholic Acid Is Superior to Ursodeoxycholic Acid in the Treatment of Sclerosing Cholangitis in Mdr2 (Abcb4) Knockout Mice

    Peter Fickert;Martin Wagner;Hanns–Ulrich Marschall;Andrea Fuchsbichler

  • Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice

    Martin Wagner;Peter Fickert;Gernot Zollner;Andrea Fuchsbichler

  • Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis

    Carolin Lackner;Margit Gogg-Kamerer;Kurt Zatloukal;Conny Stumptner

  • Mallory bodies revisited

    Helmut Denk;Cornelia Stumptner;Kurt Zatloukal

  • Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease.

    K H Preisegger;V M Factor;A Fuchsbichler;C Stumptner

  • Occurrence and immunolocalization of plectin in tissues.

    G Wiche;R Krepler;U Artlieb;R Pytela

  • Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine

    Gernot Zollner;Peter Fickert;Andrea Fuchsbichler;Dagmar Silbert

  • Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies.

    Kurt Zatloukal;Cornelia Stumptner;Manfred Lehner;Helmut Denk

  • Metaplastic breast carcinomas: are they of myoepithelial differentiation?: immunohistochemical profile of the sarcomatoid subtype using novel myoepithelial markers.

    Sebastian Leibl;Margit Gogg-Kammerer;Andrea Sommersacher;Helmut Denk

  • Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-α/β in the adaptive response to bile acids

    Gernot Zollner;Martin Wagner;Tarek Moustafa;Peter Fickert

Frequent Co-Authors

Kurt Zatloukal
Kurt Zatloukal Medical University of Graz
Michael Trauner
Michael Trauner Medical University of Vienna
Hanns-Ulrich Marschall
Hanns-Ulrich Marschall University of Gothenburg
John B. Schenkman
John B. Schenkman University of Connecticut Health Center
Werner W. Franke
Werner W. Franke German Cancer Research Center
Hartmut Jaeschke
Hartmut Jaeschke University of Kansas
Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Fattaneh A. Tavassoli
Fattaneh A. Tavassoli Yale University
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Luigi Terracciano
Luigi Terracciano University Hospital of Basel

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