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Hagai Rottenberg

Hagai Rottenberg

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
11671
World Ranking
14401
National Ranking
6063

Overview

Hagai Rottenberg is affiliated with Drexel University in the United States and has contributed extensively to the field of biochemistry, genetics, and molecular biology, with a primary focus on mitochondrial function and pathology. Their research covers a diverse range of topics including photosynthetic processes and mechanisms, autophagy in disease and therapy, genetics, aging, and longevity in model organisms, Coenzyme Q10 studies and effects, ATP synthase and ATPases research, and genomics, phytochemicals, and oxidative stress.

Their recent publications highlight detailed investigations into mitochondrial biology and aging. Notable papers include:

  • The Mitochondrial Permeability Transition: Nexus of Aging, Disease and Longevity (2021) published in Cells
  • The Reduction in the Mitochondrial Membrane Potential in Aging: The Role of the Mitochondrial Permeability Transition Pore (2023) published in International Journal of Molecular Sciences
  • The accelerated evolution of human cytochrome c oxidase - Selection for reduced rate and proton pumping efficiency? (2022) published in Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • The Reduction of Mitochondrial Membrane Potential in Aging: The Role of the Mitochondria Permeability Transition Pore (2023) published in Preprints.org
  • The evolution of the human mitochondrial bc1 complex- adaptation for reduced rate of superoxide production? (2023) published in Journal of Bioenergetics and Biomembranes

These publications reflect a focus on mitochondrial membrane potential, permeability transition pores, and the evolutionary adaptations of mitochondrial complexes, all relevant to aging and cellular bioenergetics.

Hagai Rottenberg's frequent coauthor is Jan B. Hoek, with collaborations appearing in multiple works. Their research has been disseminated across several scientific journals, including:

  • Preprints.org
  • Cells
  • International Journal of Molecular Sciences
  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • Journal of Bioenergetics and Biomembranes

Their main fields of study encompass biochemistry, genetics, and molecular biology, with substantial contributions in molecular biology, epidemiology, aging, cellular and molecular neuroscience, and ecology. Research topics strongly emphasize mitochondrial function and pathology, with additional work focused on photosynthesis, autophagy, genetics of aging, Coenzyme Q10, ATP synthase, and oxidative stress.

Best Publications

  • Determination of ΔpH in Chloroplasts

    Shimon Schuldiner;Hagai Rottenberg;Mordhay Avron

  • Atovaquone, a Broad Spectrum Antiparasitic Drug, Collapses Mitochondrial Membrane Potential in a Malarial Parasite

    Indresh K. Srivastava;Hagai Rottenberg;Akhil B. Vaidya

  • The Proton Electrochemical Gradient in Escherichia coli Cells

    Etana Padan;Dan Zilberstein;Hagai Rottenberg

  • Determination of pH in chloroplasts. I. Distribution of ( 14 C) methylamine.

    H Rottenberg;T Grunwald;M Avron

  • Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells

    Hagai Rottenberg;Shaolong Wu

  • The Measurement of Transmembrane Electrochemical Proton Gradients

    Hagai Rottenberg

  • Calcium uptake and membrane potential in mitochondria.

    Hagai Rottenberg;Antonio Scarpa

  • Respiratory Control and the Proton Electrochemical Gradient in Mitochondria

    Etana Padan;Hagai Rottenberg

  • Membrane potential and surface potential in mitochondria: uptake and binding of lipophilic cations.

    Hagai Rottenberg

  • Relation between the gradient of the ATP/ADP ratio and the membrane potential across the mitochondrial membrane.

    Martin Klingenberg;Hagai Rottenberg

  • Tolerance and cross-tolerance in chronic alcoholics: reduced membrane binding of ethanol and other drugs

    Hagai Rottenberg;Alan Waring;Emanuel Rubin

  • Membranes and phospholipids of liver mitochondria from chronic alcoholic rats are resistant to membrane disordering by alcohol

    Alan J. Waring;Hagai Rottenberg;Tomoko Ohnishi;Emanuel Rubin

  • Non-equilibrium thermodynamics of energy conversion in bioenergetics.

    Hagai Rottenberg

  • Electrochemical proton gradient in inverted membrane vesicles from Escherichia coli.

    W W Reenstra;L Patel;H Rottenberg;H R Kaback

  • P nuclear magnetic resonance studies of isolated rat liver cells.

    Cohen Sm;Ogawa S;Rottenberg H;Glynn P

  • An estimation of the light-induced electrochemical potential difference of protons across the membrane of Halobacterium halobium.

    Evert P. Bakker;Hagai Rottenberg;S.Roy Caplan

  • Fatty acid uncoupling of oxidative phosphorylation in rat liver mitochondria.

    Hagai Rottenberg;Ken Hashimoto

  • Aging Enhances the Activation of the Permeability Transition Pore in Mitochondria

    Michael Mather;Hagai Rottenberg

  • Uncoupling of oxidative phosphorylation in rat liver mitochondria by general anesthetics

    Hagai Rottenberg

  • Direct determination of ΔpH in chloroplasts, and its relation to the mechanisms of photoinduced reactions

    Hagai Rottenberg;Tilly Grunwald;Mordhay Avron

Frequent Co-Authors

Mordhay Avron
Mordhay Avron Weizmann Institute of Science
Shimon Schuldiner
Shimon Schuldiner Hebrew University of Jerusalem
Etana Padan
Etana Padan Hebrew University of Jerusalem
Uri Pick
Uri Pick Weizmann Institute of Science
Michael Eisenbach
Michael Eisenbach Weizmann Institute of Science
Rafael Moreno-Sánchez
Rafael Moreno-Sánchez University of Colorado Denver
Alan J. Waring
Alan J. Waring University of California, Los Angeles
Roger E. Koeppe
Roger E. Koeppe University of Arkansas at Fayetteville
Tomoko Ohnishi
Tomoko Ohnishi University of Pennsylvania
Robert G. Shulman
Robert G. Shulman Yale University

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