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Biology and Biochemistry

D-Index
73
Citations
20306
World Ranking
5904
National Ranking
149

Overview

H. Berna Beverloo is affiliated with Erasmus University Rotterdam in the Netherlands. Their research primarily focuses on hematology within the broader field of medicine, with a particular emphasis on leukemia and related blood cancers.

Their work covers multiple specialized topics including:

  • Acute Lymphoblastic Leukemia research
  • Acute Myeloid Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • Multiple Myeloma Research and Treatments
  • Protein Degradation and Inhibitors
  • Chronic Lymphocytic Leukemia Research
  • CAR-T cell therapy research

Beverloo's subfields of study reflect a range of disciplines related to blood disorders and oncology, including:

  • Hematology
  • Public Health, Environmental and Occupational Health
  • Molecular Biology
  • Genetics
  • Oncology

Their publication record shows frequent contributions to key medical journals, with the highest number of papers appearing in:

  • Blood
  • Journal of Clinical Oncology
  • Blood Advances
  • Leukemia
  • EJC Paediatric Oncology

Notable recent publications include:

  • Molecular characterization of mutant TP53 acute myeloid leukemia and high-risk myelodysplastic syndrome, 2022, Blood
  • The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops, 2021, Nature Communications
  • Atypical 3q26/MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia, 2020, Blood
  • Inotuzumab ozogamicin as single agent in pediatric patients with relapsed and refractory acute lymphoblastic leukemia: results from a phase II trial, 2022, Leukemia
  • Improved Outcome for ALL by Prolonging Therapy for IKZF1 Deletion and Decreasing Therapy for Other Risk Groups, 2023, Journal of Clinical Oncology

Collaborations are a significant component of their research, with frequent co-authors including:

  • Vincent H. J. van der Velden
  • Peter J.M. Valk
  • Bart J. Biemond
  • Jan J. Cornelissen
  • Michael Vermeulen

Best Publications

  • Prognostically useful gene-expression profiles in acute myeloid leukemia.

    Peter J.M. Valk;Roel G.W. Verhaak;M. Antoinette Beijen;Claudia A.J. Erpelinck

  • A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

    Monique L Den Boer;Marjon van Slegtenhorst;Renée X De Menezes;Renée X De Menezes;Meyling H Cheok

  • Monosomal Karyotype in Acute Myeloid Leukemia: A Better Indicator of Poor Prognosis Than a Complex Karyotype

    Dimitri A. Breems;Wim L. J. Van Putten;Georgine E. De Greef;Shama L. Van Zelderen-Bhola

  • Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

    Ate Loonstra;Marc Vooijs;H. Berna Beverloo;Bushra Al Allak

  • A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia

    Stefan Gröschel;Stefan Gröschel;Mathijs A Sanders;Remco Hoogenboezem;Elzo de Wit

  • The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks

    Laura J. Niedernhofer;Hanny Odijk;Magda Budzowska;Ellen van Drunen

  • New insights to the MLL recombinome of acute leukemias

    C. Meyer;E. Kowarz;J. Hofmann;A. Renneville

  • Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.

    Brian V. Balgobind;Susana C. Raimondi;Susana C. Raimondi;Jochen Harbott;Martin Zimmermann

  • The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks.

    Katsuhiro Hanada;Katsuhiro Hanada;Magda Budzowska;Sally L Davies;Ellen van Drunen

  • Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

    Irene Homminga;Rob Pieters;Anton W. Langerak;Johan J. de Rooi

  • Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

    Annemiek Broyl;Dirk Hose;Henk Lokhorst;Yvonne de Knegt

  • Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

    Roel G.W. Verhaak;Bas J. Wouters;Claudia A.J. Erpelinck;Saman Abbas

  • Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin

    Bastiaan Evers;Rinske Drost;Eva Schut;Michiel de Bruin

  • A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer

    Joaquim Calbo;Erwin van Montfort;Natalie Proost;Ellen van Drunen

  • ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair

    Anwaar Ahmad;Andria Rasile Robinson;Anette Duensing;Ellen van Drunen

  • High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patients.

    Sahar Barjesteh van Waalwijk van Doorn-Khosrovani;Claudia Erpelinck;Wim L. J. van Putten;Peter J. M. Valk

  • High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated.

    Sanne Lugthart;Ellen van Drunen;Yvette van Norden;Antoinette van Hoven

  • NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern.

    Iris H.I.M. Hollink;Marry M. van den Heuvel-Eibrink;Susan T.C.J.M. Arentsen-Peters;Marta Pratcorona

  • Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

    Idoya Lahortiga;Kim De Keersmaecker;Kim De Keersmaecker;Pieter Van Vlierberghe;Carlos Graux;Carlos Graux;Carlos Graux

  • Clinical, Molecular, and Prognostic Significance of WHO Type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and Various Other 3q Abnormalities in Acute Myeloid Leukemia

    Sanne Lugthart;Stefan Gröschel;H. Berna Beverloo;Sabine Kayser

Frequent Co-Authors

Rob Pieters
Rob Pieters Princess Máxima Center
Peter J. M. Valk
Peter J. M. Valk Erasmus University Rotterdam
Marry M. van den Heuvel-Eibrink
Marry M. van den Heuvel-Eibrink University Medical Center Utrecht
Dirk Reinhardt
Dirk Reinhardt University of Duisburg-Essen
Bob Löwenberg
Bob Löwenberg Erasmus MC
Henrik Hasle
Henrik Hasle Aarhus University Hospital
Michael Dworzak
Michael Dworzak Medical University of Vienna
Ruud Delwel
Ruud Delwel Erasmus MC
Susana C. Raimondi
Susana C. Raimondi St. Jude Children's Research Hospital

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