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D-Index
89
Citations
30990
World Ranking
12637
National Ranking
678

Overview

Guido Gerken is affiliated with the University of Duisburg-Essen in Germany and has a primary research focus in the field of Medicine, with 71 publications attributed to this area. Their work spans multiple subfields, including Epidemiology, Hepatology, Surgery, Oncology, and Molecular Biology.

Their main topics of research include:

  • Liver Disease Diagnosis and Treatment
  • Liver Diseases and Immunity
  • Pancreatitis Pathology and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Hepatitis B Virus Studies
  • Hepatitis C Virus Research
  • Hippo Pathway Signaling and YAP/TAZ

Guido Gerken has contributed to numerous scientific publications. Recent papers include:

  • "Altered Microbiota Diversity and Bile Acid Signaling in Cirrhotic and Noncirrhotic NASH-HCC," 2020, Clinical and Translational Gastroenterology
  • "Serum alpha-fetoprotein and clinical outcomes in patients with advanced hepatocellular carcinoma treated with ramucirumab," 2021, British Journal of Cancer
  • "Hepatitis B Virus Particles Activate Toll-Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes," 2020, Hepatology
  • "Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection," 2021, Frontiers in Immunology
  • "Effects of Moderate Alcohol Consumption in Non-Alcoholic Fatty Liver Disease," 2022, Journal of Clinical Medicine

Frequent co-authors in their research activities include:

  • Ali Canbay
  • Jan Best
  • Paul Manka
  • Lars P. Bechmann
  • Svenja Sydor

Guido Gerken has published extensively in various scientific venues. Among the most frequent publication venues are:

  • Zeitschrift für Gastroenterologie
  • Hepatoma Research
  • Liver International
  • Journal of Hepatology
  • Clinical and Translational Gastroenterology

Best Publications

  • Ramucirumab after sorafenib in patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations (REACH-2): a randomised, double-blind, placebo-controlled, phase 3 trial.

    Andrew X Zhu;Yoon-Koo Kang;Chia-Jui Yen;Richard S Finn

  • Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial

    Harry L A Janssen;Monika van Zonneveld;Hakan Senturk;Stefan Zeuzem

  • The interaction of hepatic lipid and glucose metabolism in liver diseases

    Lars P. Bechmann;Rebekka A. Hannivoort;Guido Gerken;Goekhan S. Hotamisligil

  • Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial.

    Jordi Bruix;Jean Luc Raoul;Morris Sherman;Vincenzo Mazzaferro

  • Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function.

    E. Cario;G. Gerken;D.K. Podolsky

  • Tivantinib for second-line treatment of advanced hepatocellular carcinoma: A randomised, placebo-controlled phase 2 study

    Armando Santoro;Lorenza Rimassa;Ivan Borbath;Bruno Daniele

  • Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C

    Elke Cario;Guido Gerken;Daniel K. Podolsky

  • Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in the absence of apparent cirrhosis

    Judith Ertle;Alexander Dechêne;Jan-Peter Sowa;Volker Penndorf

  • Radioembolization with yttrium‐90 glass microspheres in hepatocellular carcinoma: European experience on safety and long‐term survival

    Philip Hilgard;Monia Hamami;Amr El Fouly;André Scherag

  • Effects of fractionated plasma separation and adsorption on survival in patients with acute-on-chronic liver failure

    Andreas Kribben;Guido Gerken;Sebastian Haag;Stefan Herget–Rosenthal

  • All-oral daclatasvir plus asunaprevir for hepatitis C virus genotype 1b: a multinational, phase 3, multicohort study

    Michael Peter Manns;Stanislas B Pol;Ira M Jacobson;Patrick M Marcellin

  • Hepatitis B virus suppresses toll-like receptor–mediated innate immune responses in murine parenchymal and nonparenchymal liver cells

    Jun Wu;Zhongji Meng;Min Jiang;Rongjuan Pei

  • Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells.

    Percy A. Knolle;Edgar Schmitt;Shenciu Jin;Tieno Germann

  • Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium.

    Elke Cario;Dennis Brown;Mary McKee;Kathryn Lynch-Devaney

  • Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice.

    Jun Wu;Mengji Lu;Zhongji Meng;Martin Trippler

  • Polymerase Chain Reaction to Detect Hepatitis B Virus DNA and RNA Sequences in Primary Liver Cancers from Patients Negative for Hepatitis B Surface Antigen

    P. Paterlini;G. Gerken;E. Nakajima;S. Terre

  • Colitis-Associated Variant of TLR2 Causes Impaired Mucosal Repair Because of TFF3 Deficiency

    Daniel K. Podolsky;Daniel K. Podolsky;Guido Gerken;Annette Eyking;Elke Cario

  • Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid‐induced liver injury in superobese patients with nonalcoholic steatohepatitis

    Lars P. Bechmann;Peri Kocabayoglu;Peri Kocabayoglu;Jan-Peter Sowa;Svenja Sydor

  • Obesity affects the liver - the link between adipocytes and hepatocytes.

    Alexander Wree;Alisan Kahraman;Guido Gerken;Ali Canbay

  • Role of the GALAD and BALAD-2 Serologic Models in Diagnosis of Hepatocellular Carcinoma and Prediction of Survival in Patients

    Sarah Berhane;Hidenori Toyoda;Toshifumi Tada;Takashi Kumada

Frequent Co-Authors

Gerald Holtmann
Gerald Holtmann University of Queensland
Mengji Lu
Mengji Lu University of Duisburg-Essen
Daniel K. Podolsky
Daniel K. Podolsky The University of Texas at Dallas
Nicholas J. Talley
Nicholas J. Talley University of Newcastle Australia
Peter R. Galle
Peter R. Galle Johannes Gutenberg University of Mainz
Michael Roggendorf
Michael Roggendorf Technical University of Munich
Heiner Wedemeyer
Heiner Wedemeyer Hannover Medical School
Michael P. Manns
Michael P. Manns Hannover Medical School
Andreas Bockisch
Andreas Bockisch University of Duisburg-Essen
Gerald Antoch
Gerald Antoch Heinrich Heine University Düsseldorf

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