Gary J. Gorbsky focuses on Cell biology, Mitosis, Kinetochore, Spindle checkpoint and Anaphase. The concepts of his Cell biology study are interwoven with issues in Metaphase, Prometaphase, Centromere and Anaphase-promoting complex. His Mitosis research is multidisciplinary, relying on both Molecular biology, Mitotic exit and Cell cycle, Polo-like kinase.
He usually deals with Kinetochore and limits it to topics linked to Cell cycle checkpoint and BUB1. His studies in Spindle checkpoint integrate themes in fields like Mad2 and Mad2 Proteins. His study ties his expertise on Spindle apparatus together with the subject of Anaphase.
Gary J. Gorbsky focuses on Cell biology, Mitosis, Kinetochore, Spindle checkpoint and Anaphase. His work deals with themes such as Spindle apparatus, Mitotic exit, Aurora B kinase and Metaphase, which intersect with Cell biology. He combines subjects such as Chromosome, Chromosome segregation, Cell division, Molecular biology and Cell cycle with his study of Mitosis.
His work carried out in the field of Kinetochore brings together such families of science as Cell cycle checkpoint and Cohesin. His Spindle checkpoint research is multidisciplinary, incorporating elements of Mad2, Mitotic spindle checkpoint, BUB1, PLK1 and Anaphase-promoting complex. His Anaphase study integrates concerns from other disciplines, such as Interphase and Phosphorylation.
Gary J. Gorbsky mainly focuses on Cell biology, Mitosis, Kinetochore, Spindle apparatus and Spindle checkpoint. Gary J. Gorbsky has researched Cell biology in several fields, including Metaphase, Anaphase, Aurora B kinase and Spindle pole body. His Metaphase research is multidisciplinary, incorporating perspectives in Establishment of sister chromatid cohesion and Cohesin.
His research in Aurora B kinase tackles topics such as Chromosome movement which are related to areas like Astral microtubules and Mitotic exit. His study in Mitosis is interdisciplinary in nature, drawing from both Cell cycle, Chromosome, Chromosome segregation and Cell division. His Microtubule study incorporates themes from Prometaphase and Meiosis.
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Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.
R B Nicklas;S C Ward;G J Gorbsky.
Journal of Cell Biology (1995)
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis
Fangwei Wang;Jun Dai;John R. Daum;Ewa Niedzialkowska.
Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis.
Marko J. Kallio;Mark L. McCleland;P.Todd Stukenberg;Gary J. Gorbsky.
Current Biology (2002)
Mammalian p55CDC Mediates Association of the Spindle Checkpoint Protein Mad2 with the Cyclosome/Anaphase-promoting Complex, and is Involved in Regulating Anaphase Onset and Late Mitotic Events
Marko Kallio;Jasminder Weinstein;John R. Daum;Daniel J. Burke.
Journal of Cell Biology (1998)
Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.
Gary J. Gorbsky;Paul J. Sammak;Gary G. Borisy.
Journal of Cell Biology (1987)
Regulation of microtubule stability and mitotic progression by survivin.
Alessandra Giodini;Marko J. Kallio;Nathan R. Wall;Gary J. Gorbsky.
Cancer Research (2002)
Differential expression of a phosphoepitope at the kinetochores of moving chromosomes
Gary J. Gorbsky;William A. Ricketts.
Journal of Cell Biology (1993)
Microinjection of Antibody to Mad2 Protein into Mammalian Cells in Mitosis Induces Premature Anaphase
Gary J. Gorbsky;Rey Huei Chen;Andrew W. Murray.
Journal of Cell Biology (1998)
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity
Mark L. McCleland;Richard D. Gardner;Marko J. Kallio;John R. Daum.
Genes & Development (2003)
Isolation of the intercellular glycoproteins of desmosomes.
G Gorbsky;M S Steinberg.
Journal of Cell Biology (1981)
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