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Francisco García-Cánovas

Francisco García-Cánovas

D-Index & Metrics

Chemistry

D-Index
66
Citations
14719
World Ranking
7325
National Ranking
216

Overview

Francisco García-Cánovas is affiliated with the University of Murcia in Spain. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, as well as Nursing. Subfields of particular interest include Cell Biology, Nutrition and Dietetics, Biochemistry, Sensory Systems, and Dermatology.

Their work covers a range of main topics, with a pronounced emphasis on melanin and skin pigmentation, biochemical analysis and sensing techniques, and phytochemicals and antioxidant activities. Other notable areas of study include olfactory and sensory function studies, enzyme-mediated dye degradation, skin protection and aging, and acne and rosacea treatments and effects.

Frequent publication venues for García-Cánovas include the International Journal of Biological Macromolecules and Food Chemistry, each featuring two of their publications. Other journals where their work has appeared are Biochemical Pharmacology, Molecular Catalysis, and Molecules.

Frequent collaborators in their research activities are José Muñoz-Muñoz, Francisco García-Molina, José Neptuno Rodrı́guez-López, Pablo García-Molina, and José A. Teruel.

Their recent published papers include:

  • "Targeting tyrosinase in hyperpigmentation: Current status, limitations and future promises," 2023, published in Biochemical Pharmacology
  • "Considerations about the kinetic mechanism of tyrosinase in its action on monophenols: A review," 2022, published in Molecular Catalysis
  • "The Relationship between the IC50 Values and the Apparent Inhibition Constant in the Study of Inhibitors of Tyrosinase Diphenolase Activity Helps Confirm the Mechanism of Inhibition," 2022, published in Molecules
  • "Study of tyrosine and dopa enantiomers as tyrosinase substrates initiating l- and d-melanogenesis pathways," 2020, published in Biotechnology and Applied Biochemistry
  • "Kinetic characterization of the oxidation of catecolamines and related compounds by laccase," 2020, published in International Journal of Biological Macromolecules

Best Publications

  • Tyrosinase: a comprehensive review of its mechanism.

    Álvaro Sánchez-Ferrer;José Neptuno Rodríguez-López;Francisco García-Cánovas;Francisco García-Carmona

  • A comprehensive review on tyrosinase inhibitors.

    Samaneh Zolghadri;Asieh Bahrami;Mahmud Tareq Hassan Khan;J. Munoz-Munoz

  • An end‐point method for estimation of the total antioxidant activity in plant material

    Antonio Cano;Josefa Hernández-Ruíz;Francisco García-Cánovas;Manuel Acosta

  • Mechanism of Reaction of Hydrogen Peroxide with Horseradish Peroxidase: Identification of Intermediates in the Catalytic Cycle

    Jose Neptuno Rodriguez-Lopez;David J. Lowe;Josefa Hernandez-Ruiz;Alexander N. P. Hiner

  • A kinetic study on the suicide inactivation of peroxidase by hydrogen peroxide.

    M.B. Arnao;M. Acosta;J.A. del Rio;R. Varón

  • Analysis of a kinetic model for melanin biosynthesis pathway.

    J N Rodríguez-López;J Tudela;R Varón;F García-Carmona

  • Kinetic characterization of the substrate specificity and mechanism of mushroom tyrosinase

    Juan C. Espín;Ramón Varón;Lorena G. Fenoll;M. Angeles Gilabert

  • Inactivation of peroxidase by hydrogen peroxide and its protection by a reductant agent

    M.B. Arnao;M. Acosta;J.A. del Rio;F. García-Cánovas

  • Mechanisms of compound I formation in heme peroxidases.

    Alexander N.P. Hiner;Emma L. Raven;Roger N.F. Thorneley;Francisco Garcı́a-Cánovas

  • The antifolate activity of tea catechins.

    Enma Navarro-Perán;Juan Cabezas-Herrera;Francisco García-Cánovas;Marcus C. Durrant

  • Catalase-like activity of horseradish peroxidase: relationship to enzyme inactivation by H2O2.

    Josefa Hernández-Ruiz;Marino B. Arnao;Alexander N.P. Hiner;Francisco García-Cánovas

  • Effect of L-ascorbic acid on the monophenolase activity of tyrosinase

    J R Ros;J N Rodríguez-López;F García-Cánovas

  • A CONTINUOUS SPECTROPHOTOMETRIC METHOD FOR DETERMINING THE MONOPHENOLASE AND DIPHENOLASE ACTIVITIES OF APPLE POLYPHENOL OXIDASE

    J.C. Espin;M. Morales;R. Varon;J. Tudela

  • A kinetic study of the melanization pathway between L-tyrosine and dopachrome.

    Juana Cabanes;Francisco García-Cánovas;JoséA. Lozano;Francisco García-Carmona

  • Analysis and interpretation of the action mechanism of mushroom tyrosinase on monophenols and diphenols generating highly unstable o-quinones.

    Lorena G. Fenoll;José Neptuno Rodrı́guez-López;Francisco Garcı́a-Sevilla;Pedro Antonio Garcı́a-Ruiz

  • A Review on Spectrophotometric Methods for Measuring the Monophenolase and Diphenolase Activities of Tyrosinase

    F. García-Molina;J. L. Muñoz;R. Varón;J. N. Rodríguez-López

  • Reactivity of horseradish peroxidase compound II toward substrates: kinetic evidence for a two-step mechanism.

    José Neptuno Rodríguez-López;María Angeles Gilabert;José Tudela;Roger N. F. Thorneley

  • A Continuous Spectrophotometric Method for the Determination of Monophenolase Activity of Tyrosinase Using 3-Methyl-2-benzothiazolinone Hydrazone

    J.N. Rodriguezlopez;J. Escribano;F. Garciacanovas

  • Tyrosinase kinetics: discrimination between two models to explain the oxidation mechanism of monophenol and diphenol substrates

    L.G. Fenoll;M.J. Peñalver;J.N. Rodrı́guez-López;R. Varón

  • Enzyme inactivation analysis for industrial blanching applications: comparison of microwave, conventional, and combination heat treatments on mushroom polyphenoloxidase activity.

    C. Devece;J. N. Rodriguez-Lopez;L. G. Fenoll;J. Tudela

Frequent Co-Authors

Francisco García-Carmona
Francisco García-Carmona University of Murcia
Marino B. Arnao
Marino B. Arnao University of Murcia
Juan Carlos Espín
Juan Carlos Espín Spanish National Research Council
Roger N. F. Thorneley
Roger N. F. Thorneley John Innes Centre
Juan C. Gómez-Fernández
Juan C. Gómez-Fernández University of Murcia
Emma Lloyd Raven
Emma Lloyd Raven University of Bristol
Ronald G. Duggleby
Ronald G. Duggleby University of Queensland
Giulietta Smulevich
Giulietta Smulevich University of Florence
Ali Akbar Saboury
Ali Akbar Saboury University of Tehran

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