David R. Kaplan

Best Publications

• Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

  Henryk Dudek;Sandeep Robert Datta;Thomas F. Franke;Morris J. Birnbaum

  3110
  Citations

• Neurotrophin signal transduction in the nervous system.

  David R Kaplan;Freda D Miller

  2543
  Citations

• Isolation of multipotent adult stem cells from the dermis of mammalian skin

  Jean G. Toma;Mahnaz Akhavan;Karl J. L. Fernandes;Fanie Barnabé-Heider

  2185
  Citations

• Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

  Thomas F. Franke;David R. Kaplan;Lewis C. Cantley;Alex Toker

  1995
  Citations

• The trk proto-oncogene product: a signal transducing receptor for nerve growth factor

  David R. Kaplan;Barbara L. Hempstead;Dionisio Martin-Zanca;Moses V. Chao

  1714
  Citations

• TYROSINE PHOSPHORYLATION AND TYROSINE KINASE ACTIVITY OF THE TRK PROTO-ONCOGENE PRODUCT INDUCED BY NGF

  David R. Kaplan;Dionisio Martin-Zanca;Luis F. Parada

  1303
  Citations

• Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB.

  Lucy R. Berkemeier;John W. Winslow;David R. Kaplan;Karoly Nikolics

  1123
  Citations

• The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

  Dan Soppet;Enrique Escandon;Johnne Maragos;David S. Middlemas

  943
  Citations

• Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

  David R. Kaplan;Malcolm Whitman;Brian Schaffhausen;David C. Pallas

  783
  Citations

• Signal transduction by the neutrophin receptors

  David R Kaplan;Freda D Miller

  775
  Citations

• Trk receptors use redundant signal transduction pathways involving SHC and PLC-γ1 to mediate NGF responses

  Robert M. Stephens;David M. Loeb;Terry D. Copeland;Tony Pawson

  740
  Citations

• Neurotrophin signal transduction by the Trk receptor.

  David R. Kaplan;Robert M. Stephens

  698
  Citations

• An anti-apoptotic role for the p53 family member, p73, during developmental neuron death.

  Christine D. Pozniak;Stevo Radinovic;Annie Yang;Frank McKeon

  623
  Citations

• The TrkB-Shc Site Signals Neuronal Survival and Local Axon Growth via MEK and PI3-Kinase

  Jasvinder K Atwal;Bernard Massie;Freda D Miller;David R Kaplan

  548
  Citations

• Early events in neurotrophin signalling via Trk and p75 receptors.

  Lloyd A Greene;David R Kaplan

  445
  Citations

• BDNF Promotes the Regenerative Sprouting, But Not Survival, of Injured Serotonergic Axons in the Adult Rat Brain

  Laura A. Mamounas;C. Anthony Altar;Mary E. Blue;David R. Kaplan

  431
  Citations

• p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

  Joseph M. Verdi;Susan J. Birren;Carlos F. Ibáñez;Håkan Persson

  429
  Citations

• Evidence that Embryonic Neurons Regulate the Onset of Cortical Gliogenesis via Cardiotrophin-1

  Fanie Barnabé-Heider;Julie A. Wasylnka;Karl J.L. Fernandes;Christian Porsche

  421
  Citations

• P53 IS ESSENTIAL FOR DEVELOPMENTAL NEURON DEATH AS REGULATED BY THE TRKA AND P75 NEUROTROPHIN RECEPTORS

  Raquel S. Aloyz;Shernaz X. Bamji;Christine D. Pozniak;Jean G. Toma

  415
  Citations

• Neurotrophin signalling pathways regulating neuronal apoptosis.

  F.D. Miller;D.R. Kaplan

  404
  Citations