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Genetics

D-Index
59
Citations
12701
World Ranking
3239
National Ranking
1407

Overview

Brett H. Graham is affiliated with Baylor College of Medicine in the United States. Their research spans primarily the fields of Biochemistry, Genetics, and Molecular Biology, with a substantial focus in Medicine. The subfields of their studies include Molecular Biology, Genetics, Physiology, Clinical Biochemistry, and Epidemiology.

The main topics covered in their research encompass:

  • Metabolism and Genetic Disorders
  • Mitochondrial Function and Pathology
  • Genomics and Rare Diseases
  • Genomic Variations and Chromosomal Abnormalities
  • Diet and Metabolism Studies
  • Adipose Tissue and Metabolism
  • Liver Disease Diagnosis and Treatment

They have contributed to multiple frequent publication venues, including:

  • Genetics in Medicine Open
  • Molecular Genetics and Metabolism
  • Genetics in Medicine
  • American Journal of Medical Genetics Part A
  • Translational Psychiatry

Among the notable recent papers authored or coauthored by Brett H. Graham are:

  • Impaired mitochondrial complex I function as a candidate driver in the biological stress response and a concomitant stress-induced brain metabolic reprogramming in male mice, 2020, Translational Psychiatry
  • Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial, 2021, The American Journal of Medicine
  • UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism, 2020, The American Journal of Human Genetics
  • MED27 Variants Cause Developmental Delay, Dystonia, and Cerebellar Hypoplasia, 2021, Annals of Neurology
  • Succinyl-CoA Synthetase Dysfunction as a Mechanism of Mitochondrial Encephalomyopathy: More than Just an Oxidative Energy Deficit, 2023, International Journal of Molecular Sciences

Their frequent coauthors include Erin Conboy, Patrick J. Gillespie, Kayla Treat, Benjamin M. Helm, and Francesco Vetrini. The collaboration with these colleagues indicates active partnerships in their research projects.

Best Publications

  • Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

    Lucy Liu;Ke Zhang;Hector Sandoval;Shinya Yamamoto;Shinya Yamamoto

  • Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities

    Nicola Brunetti-Pierri;Jonathan S. Berg;Fernando Scaglia;John Belmont

  • A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

    Brett H. Graham;Katrina G. Waymire;Barbara Cottrell;Ian A. Trounce

  • Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.

    Michael D Hill;Mayank Goyal;Bijoy K Menon;Raul G Nogueira

  • Recurrent reciprocal 16p11.2 rearrangements associated with global developmental delay, behavioural problems, dysmorphism, epilepsy, and abnormal head size

    Marwan Shinawi;Pengfei Liu;Sung Hae L Kang;Joseph Shen

  • Sox9 and NFIA Coordinate a Transcriptional Regulatory Cascade during the Initiation of Gliogenesis

    Peng Kang;Hyun Kyoung Lee;Stacey M. Glasgow;Meggie Finley

  • Use of Exome Sequencing for Infants in Intensive Care Units: Ascertainment of Severe Single-Gene Disorders and Effect on Medical Management

    Linyan Meng;Linyan Meng;Mohan Pammi;Anirudh Saronwala;Pilar Magoulas;Pilar Magoulas

  • Marked changes in mitochondrial DNA deletion levels in Alzheimer brains

    M Corral-Debrinski;T Horton;M T Lott;J M Shoffner

  • Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer

    Jun Hyoung Park;Sajna Vithayathil;Santosh Kumar;Pi Lin Sung;Pi Lin Sung

  • The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies

    Claire Redin;Claire Redin;Harrison Brand;Harrison Brand;Ryan L Collins;Ryan L Collins;Tammy Kammin

  • Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway

    Gregory M. Enns;Vandana Shashi;Matthew Bainbridge;Michael J. Gambello

  • Lessons learned from additional research analyses of unsolved clinical exome cases

    Mohammad K. Eldomery;Mohammad K. Eldomery;Zeynep Coban-Akdemir;Tamar Harel;Jill A. Rosenfeld

  • Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans

    Vafa Bayat;Isabelle Thiffault;Isabelle Thiffault;Manish Jaiswal;Martine Tétreault

  • MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.

    Julia Wang;Rami Al-Ouran;Yanhui Hu;Seon-Young Kim

  • Mutations in FBXL4 Cause Mitochondrial Encephalopathy and a Disorder of Mitochondrial DNA Maintenance

    Penelope E. Bonnen;John W. Yarham;Arnaud Besse;Ping Wu

  • Clinical course of sly syndrome (mucopolysaccharidosis type VII)

    Adriana M Montaño;Ngu Lock-Hock;Robert D Steiner;Brett H Graham

  • De novo truncating mutations in ASXL3 are associated with a novel clinical phenotype with similarities to Bohring-Opitz syndrome

    Matthew N Bainbridge;Hao Hu;Donna M Muzny;Luciana Musante

  • Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes.

    Tamar Harel;Wan Hee Yoon;Caterina Garone;Shen Gu

  • Mitochondrial biology, degenerative diseases and aging

    Douglas C. Wallace;Michael D. Brown;Simon Melov;Brett Graham

  • The Undiagnosed Diseases Network: Accelerating Discovery about Health and Disease

    Rachel B. Ramoni;Rachel B. Ramoni;John J. Mulvihill;David R. Adams;Patrick Allard

Frequent Co-Authors

William J. Craigen
William J. Craigen Baylor College of Medicine
Hugo J. Bellen
Hugo J. Bellen Baylor College of Medicine
Seema R. Lalani
Seema R. Lalani Baylor College of Medicine
Lee-Jun C. Wong
Lee-Jun C. Wong Baylor College of Medicine
Jill A. Rosenfeld
Jill A. Rosenfeld Baylor College of Medicine
Brendan Lee
Brendan Lee Baylor College of Medicine
Christine M. Eng
Christine M. Eng Baylor College of Medicine
James R. Lupski
James R. Lupski Baylor College of Medicine
Donna M. Muzny
Donna M. Muzny Baylor College of Medicine
Richard A. Gibbs
Richard A. Gibbs Baylor College of Medicine

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