World's Best Scientists 2026 revealed!

Overview

Bita Esmaeli is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans multiple areas within medicine, particularly focusing on oncology, surgery, ophthalmology, epidemiology, and dermatology. Their scholarly work involves a detailed exploration of ocular oncology and treatments, nonmelanoma skin cancer studies, ear and head tumors, salivary gland tumors diagnosis and treatment, cancer and skin lesions, oral and maxillofacial pathology, and cancer immunotherapy and biomarkers.

Esmaeli's recent publications reflect ongoing contributions to clinical and translational research in cancer and ophthalmic oncology. Selected recent papers include:

  • Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck, 2021, Clinical Cancer Research
  • Conjunctival melanoma: New insights in tumour genetics and immunology, leading to new therapeutic options, 2021, Progress in Retinal and Eye Research
  • Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy, 2020, Journal for ImmunoTherapy of Cancer
  • Immune Checkpoint Inhibitor Therapy as an Eye-Preserving Treatment for Locally Advanced Conjunctival Melanoma, 2020, Ophthalmic Plastic and Reconstructive Surgery
  • The 5th Edition of the World Health Organization Classification of Tumours of the Eye and Orbit, 2023, Ocular Oncology and Pathology

The scientist collaborates frequently with several colleagues, including Renata Ferrarotto, J. Matthew Debnam, Jing Ning, Priyadharsini Nagarajan, and Steven J. Frank. Their work often appears in specialized publication venues with multiple contributions in:

  • Ophthalmic Plastic and Reconstructive Surgery
  • British Journal of Ophthalmology
  • Journal of Clinical Oncology
  • Investigative Ophthalmology & Visual Science
  • Clinical Cancer Research

Their research areas branch into various subfields of medicine with a strong emphasis on the treatment and diagnosis of cancers affecting the eye and surrounding tissues. Esmaeli's work engages deeply with oncology, emphasizing surgery and the epidemiology of ocular malignancies. This multidisciplinary focus informs advances in understanding tumors of the eye and head and neck region, including targeted immunotherapy approaches.

Esmaeli's body of work contributes particularly to developing therapeutic options for rare and complex cancers such as conjunctival and uveal melanoma as well as cutaneous squamous cell carcinoma. By addressing molecular profiles and immune responses, their research plays a role in advancing immunotherapy and eye-preserving treatments.

Best Publications

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Phase I and Pharmacokinetic Study of ABI-007, a Cremophor-free, Protein-stabilized, Nanoparticle Formulation of Paclitaxel

    Nuhad K. Ibrahim;Neil Desai;Sewa Legha;Patrick Soon-Shiong

  • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

    A. Gordon Robertson;Juliann Shih;Juliann Shih;Christina Yau;Ewan A. Gibb

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Phase II Study of Weekly Docetaxel and Trastuzumab for Patients With HER-2–Overexpressing Metastatic Breast Cancer

    Francisco J. Esteva;Vicente Valero;Daniel Booser;Laura T. Guerra

  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi

  • Uveal Melanoma: From Diagnosis to Treatment and the Science in Between

    Chandrani Chattopadhyay;Dae Won Kim;Dan S. Gombos;Junna Oba

  • Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

    Joshua D. Campbell;Joshua D. Campbell;Joshua D. Campbell;Christina Yau;Christina Yau;Reanne Bowlby;Yuexin Liu

  • Metastatic tumors of the orbit and ocular adnexa.

    S Mehdi Ahmad;Bita Esmaeli

  • Successful treatment of Erdheim-Chester disease, a non–Langerhans-cell histiocytosis, with interferon-α

    Fadi Braiteh;Cynthia Boxrud;Cynthia Boxrud;Cynthia Boxrud;Bita Esmaeli;Razelle Kurzrock;Razelle Kurzrock;Razelle Kurzrock

  • Visual Outcome and Ocular Survival after Penetrating Trauma: A Clinicopathologic Study

    Bita Esmaeli;S. G. Elner;M. A. Schork;V. M. Elner

  • Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

    Hua-Sheng Chiu;Sonal Somvanshi;Ektaben Patel;Ting-Wen Chen

  • Patterns of regional and distant metastasis in patients with eyelid and periocular squamous cell carcinoma

    Misha Faustina;Roxana Diba;M.Amir Ahmadi;Brett F. Gutstein

  • Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ- and GNA11-Dependent Manner

    Jahan S. Khalili;Xiaoxing Yu;Ji Wang;Brendan C. Hayes

  • Outcomes in patients with adenoid cystic carcinoma of the lacrimal gland.

    Bita Esmaeli;Amir A. Ahmadi;Adel Youssef;Roxana Diba

  • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma (vol 32, pg 204, 2017)

    A.G. Robertson;J.L. Shih;C. Yau;E.A. Gibb

Frequent Co-Authors

Victor G. Prieto
Victor G. Prieto The University of Texas MD Anderson Cancer Center
Alexander J. Lazar
Alexander J. Lazar The University of Texas MD Anderson Cancer Center
William H. Morrison
William H. Morrison The University of Texas MD Anderson Cancer Center
Adel K. El-Naggar
Adel K. El-Naggar The University of Texas MD Anderson Cancer Center
David I. Rosenthal
David I. Rosenthal The University of Texas MD Anderson Cancer Center
Adam S. Garden
Adam S. Garden The University of Texas MD Anderson Cancer Center
Jeffrey E. Gershenwald
Jeffrey E. Gershenwald The University of Texas MD Anderson Cancer Center
Andrew D. Cherniack
Andrew D. Cherniack Broad Institute
Jeffrey N. Myers
Jeffrey N. Myers The University of Texas MD Anderson Cancer Center
Christina Yau
Christina Yau University of California, San Francisco

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