Alfons Billiau

Overview

Best Publications

• Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

  J Van Damme;G Opdenakker;R J Simpson;M R Rubira

  808
  Citations

• AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice.

  Patrick Matthys;Sigrid Hatse;Kurt Vermeire;Anja Wuyts

  398
  Citations

• Human Interferon: Mass Production in a Newly Established Cell Line, MG-63

  A. Billiau;V. G. Edy;Hubertine Heremans;J. Van Damme

  377
  Citations

• A novel, NH2-terminal sequence-characterized human monokine possessing neutrophil chemotactic, skin-reactive, and granulocytosis-promoting activity.

  J Van Damme;J Van Beeumen;G Opdenakker;A Billiau

  373
  Citations

• Interferon gamma, a mediator of lethal lipopolysaccharide-induced Shwartzman-like shock reactions in mice.

  H Heremans;J Van Damme;C Dillen;R Dijkmans

  320
  Citations

• Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1

  J Van Damme;M De Ley;G Opdenakker;A Billiau

  298
  Citations

• Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein

  K. Gijbels;K. Gijbels;P. Proost;S. Masure;H. Carton

  286
  Citations

• Interleukin 1 and poly(rI) · poly(rC) induce production of a hybridoma growth factor by human fibroblasts

  Jo Van Damme;Sylvie Cayphas;Ghislain Opdenakker;Alfons Billiau

  249
  Citations

• How interferon-γ keeps autoimmune diseases in check

  Hilde Kelchtermans;Alfons Billiau;Patrick Matthys

  233
  Citations

• Induction of a 26-kDa-protein mRNA in human cells treated with an interleukin-1-related, leukocyte-derived factor

  Lucas De Wit;Pascale Poupart;Ghislain Opdenakker

  221
  Citations

• Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ

  Hilde Kelchtermans;Bert De Klerck;Tania Mitera;Maarten Van Balen

  218
  Citations

• Severe cachexia in mice inoculated with interferon‐γ‐producing tumor cells

  Patrick Matthys;Roger Dukmans;Paul Proost;Jo Van Damme

  218
  Citations

• Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis

  Koen Gijbels;Jo van Damme;Paul Proost;Willy Put

  217
  Citations

• Interleukin-1 stimulates steroidogenesis in cultured rat Leydig cells.

  Guido Verhoeven;Jean Cailleau;Jozef Van Damme;Alfons Billiau

  193
  Citations

• The chemotactic activity for granulocytes produced by virally infected fibroblasts is identical to monocyte-derived interleukin 8.

  Jo Van Damme;Jo Van Damme;Benny Decock;Renè Conings;Jean‐Pierre Lenaerts

  186
  Citations

• Protective effect of anti-interleukin (IL)-6 antibody against endotoxin, associated with paradoxically increased IL-6 levels.

  Hubertine Heremans;Chris Dillen;Willy Put;Jo Van Damme

  184
  Citations

• Administration of human fibroblast interferon in chronic hepatitis-B infection.

  J Desmyter;J De Groote;V.J Desmet;A Billiau

  182
  Citations

• Interferon treatment of NZB mice: accelerated progression of autoimmune disease.

  Hubertine Heremans;Alfons Billiau;A Colombatti;J Hilgers

  180
  Citations

• Antiviral Activity of Polyacrylic and Polymethacrylic Acids I. Mode of Action in Vitro.

  P. De Somer;E. De Clercq;A. Billiau;E. Schonne

  176
  Citations

• Purification and characterization of human fibroblast‐derived hybridoma growth factor identical to T‐cell‐derived B‐cell stimulatory factor‐2 (interleukin‐6)

  Jo Van Damme;Sylvie Cayphas;Jacques Van Snick;René Conings

  163
  Citations