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Alexej Abyzov

Alexej Abyzov

D-Index & Metrics

Genetics

D-Index
48
Citations
64737
World Ranking
4010
National Ranking
1729

Overview

Alexej Abyzov is affiliated with the Mayo Clinic in the United States and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Genetics, Cancer Research, Cognitive Neuroscience, and Pediatrics, Perinatology and Child Health.

Their research covers a range of topics such as:

  • Cancer Genomics and Diagnostics
  • Single-cell and spatial transcriptomics
  • Genomic variations and chromosomal abnormalities
  • Genomics and Rare Diseases
  • CRISPR and Genetic Engineering
  • Epigenetics and DNA Methylation
  • Genomics and Chromatin Dynamics

Abyzov has published in several prominent scientific venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Nature Neuroscience
  • Neuro-Oncology
  • Nature Communications

Some of the recent papers authored by Abyzov include:

  • "The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing," 2021, Nature Neuroscience
  • "Landmarks of human embryonic development inscribed in somatic mutations," 2021, Science
  • "CNVpytor: a tool for copy number variation detection and analysis from read depth and allele imbalance in whole-genome sequencing," 2021, GigaScience
  • "Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development," 2023, Nature Genetics
  • "Single-cell multi-cohort dissection of the schizophrenia transcriptome," 2024, Science

Frequent collaborators in their research include:

  • Flora M. Vaccarino
  • Taejeong Bae
  • Yifan Wang
  • Yeongjun Jang
  • Christopher A. Walsh

Best Publications

  • A global reference for human genetic variation.

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • An integrated map of genetic variation from 1,092 human genomes

    Goncalo R Abecasis;Adam Auton;Lisa D Brooks

  • Table S2: Trans-factors and trinucleotide repeat instability Trans-factor

    Arturo López Castel;John D Cleary;Christopher E Pearson

  • An integrated encyclopedia of DNA elements in the human genome

    Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins

  • An integrated map of structural variation in 2,504 human genomes

    Peter H. Sudmant;Tobias Rausch;Eugene J. Gardner;Robert E. Handsaker;Robert E. Handsaker

  • Architecture of the human regulatory network derived from ENCODE data

    Mark B Gerstein;Anshul Kundaje;Manoj Hariharan;Stephen G Landt

  • CNVnator: An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

    Alexej Abyzov;Alexander Eckehart Urban;Michael Snyder;Mark Gerstein

  • A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

    Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham

  • Mapping copy number variation by population-scale genome sequencing

    Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker

  • FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

    Jessica Mariani;Gianfilippo Coppola;Ping Zhang;Alexej Abyzov

  • A global reference for human genetic variation

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • A map of human genome variation from population-scale sequencing

    Richard M. Durbin;David L. Altshuler;Gonçalo R. Abecasis;David R. Bentley

  • Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells

    Alexej Abyzov;Jessica Mariani;Dean Palejev;Ying Zhang

  • The PsychENCODE project

    Schahram Akbarian;Chunyu Liu;James A Knowles;Flora M Vaccarino

  • Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics

    Ekta Khurana;Yao Fu;Vincenza Colonna;Vincenza Colonna;Xinmeng Jasmine Mu

  • AlleleSeq: analysis of allele-specific expression and binding in a network framework

    Joel Rozowsky;Alexej Abyzov;Jing-jing Wang;Pedro Luz Alves

  • PEMer: a computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data

    Jan O. Korbel;Jan O. Korbel;Alexej Abyzov;Xinmeng Jasmine Mu;Nicholas J. Carriero

  • Transcriptome and epigenome landscape of human cortical development modeled in organoids

    Anahita Amiri;Gianfilippo Coppola;Soraya Scuderi;Feinan Wu

  • Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network

    Michael J. McConnell;John V. Moran;Alexej Abyzov;Schahram Akbarian

  • Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis

    Taejeong Bae;Livia Tomasini;Jessica Mariani;Bo Zhou

Frequent Co-Authors

Mark Gerstein
Mark Gerstein Yale University
Flora M. Vaccarino
Flora M. Vaccarino Yale University
Michael Snyder
Michael Snyder Stanford University
Jan O. Korbel
Jan O. Korbel European Molecular Biology Laboratory
Sherman M. Weissman
Sherman M. Weissman Yale University
Jeffrey M. Kidd
Jeffrey M. Kidd University of Michigan–Ann Arbor
Steven A. McCarroll
Steven A. McCarroll Harvard University
Paul Flicek
Paul Flicek The Jackson Laboratory
Emmanouil T. Dermitzakis
Emmanouil T. Dermitzakis University of Geneva
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research

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