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Flora M. Vaccarino

Flora M. Vaccarino

D-Index & Metrics

Neuroscience

D-Index
69
Citations
16950
World Ranking
2631
National Ranking
1242

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Flora M. Vaccarino is affiliated with Yale University in the United States. Their research focuses primarily on the fields of Biochemistry, Genetics, and Molecular Biology, with particular attention to molecular biology and genetics. Additional areas of study include cancer research, clinical psychology, and cognitive neuroscience.

The scientist's work covers a range of topics including single-cell and spatial transcriptomics, cancer genomics and diagnostics, CRISPR and genetic engineering, pluripotent stem cell research, genomics and rare diseases, obsessive-compulsive spectrum disorders, and genomic variations and chromosomal abnormalities.

Recent publications include:

  • "A nomenclature consensus for nervous system organoids and assembloids" (2022, Nature)
  • "The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing" (2021, Nature Neuroscience)
  • "Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity" (2020, American Journal of Psychiatry)
  • "Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis" (2023, Nature Neuroscience)
  • "Early developmental asymmetries in cell lineage trees in living individuals" (2021, Science)

Frequent collaborators in their research include Alexej Abyzov, Taejeong Bae, Jessica Mariani, Yeongjun Jang, and Alexandre Jourdon. These collaborations have contributed to numerous studies across related scientific disciplines.

Flora M. Vaccarino has published extensively in multiple venues, with a significant number of publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Neuroscience
  • Nature Communications
  • Nature
  • Science

Among recognitions received, Flora M. Vaccarino was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2013.

Best Publications

  • FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

    Jessica Mariani;Gianfilippo Coppola;Ping Zhang;Alexej Abyzov

  • Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome.

    Paul S. A. Kalanithi;Wei Zheng;Yuko Kataoka;Marian DiFiglia

  • Altering the course of schizophrenia: progress and perspectives

    Mark J. Millan;Annie Andrieux;George Bartzokis;Kristin Cadenhead

  • Modeling human cortical development in vitro using induced pluripotent stem cells

    Jessica Mariani;Maria Vittoria Simonini;Dean Palejev;Livia Tomasini

  • Basic Fibroblast Growth Factor (Fgf2) Is Necessary for Cell Proliferation and Neurogenesis in the Developing Cerebral Cortex

    Rossana Raballo;Julianne Rhee;Richard Lyn-Cook;James F. Leckman

  • Decreased Number of Parvalbumin and Cholinergic Interneurons in the Striatum of Individuals with Tourette Syndrome

    Yuko Kataoka;Paul S.A. Kalanithi;Heidi Grantz;Michael L. Schwartz

  • Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus.

    Joshua J. Breunig;John Silbereis;Flora M. Vaccarino;Nenad Šestan

  • Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis

    Flora M. Vaccarino;Michael L. Schwartz;Rossana Raballo;Jon Nilsen

  • The PsychENCODE project

    Schahram Akbarian;Chunyu Liu;James A Knowles;Flora M Vaccarino

  • Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.

    F Vaccarino;A Guidotti;E Costa

  • Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

    Jae Geun Kim;Shigetomo Suyama;Marco Koch;Sungho Jin

  • Transcriptome and epigenome landscape of human cortical development modeled in organoids

    Anahita Amiri;Gianfilippo Coppola;Soraya Scuderi;Feinan Wu

  • Early Postnatal Astroglial Cells Produce Multilineage Precursors and Neural Stem Cells In Vivo

    Yosif M. Ganat;John Silbereis;Clinton Cave;Hai Ngu

  • Neurobiology of premature brain injury

    Natalina Salmaso;Beata Jablonska;Joseph Scafidi;Flora M Vaccarino

  • Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network

    Michael J. McConnell;John V. Moran;Alexej Abyzov;Schahram Akbarian

  • Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis

    Taejeong Bae;Livia Tomasini;Jessica Mariani;Bo Zhou

  • Fibroblast growth factor 2 is required for maintaining the neural stem cell pool in the mouse brain subventricular zone.

    Wei Zheng;Richard S Nowakowski;Flora M Vaccarino

  • Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene.

    Dario Acampora;Maria Pia Postiglione;Virginia Avantaggiato;Maria Di Bonito

  • Transcriptome Analysis of the Human Striatum in Tourette Syndrome

    Jessica B. Lennington;Gianfilippo Coppola;Yuko Kataoka-Sasaki;Thomas V. Fernandez

  • Pyramidal Neurons Are Generated from Oligodendroglial Progenitor Cells in Adult Piriform Cortex

    Fuzheng Guo;Yoshiko Maeda;Joyce Ma;Jie Xu

Frequent Co-Authors

Alexej Abyzov
Alexej Abyzov Mayo Clinic
Michael L. Schwartz
Michael L. Schwartz Yale University
Laura R. Ment
Laura R. Ment Yale University
Nenad Sestan
Nenad Sestan Yale University
Sherman M. Weissman
Sherman M. Weissman Yale University
Ronald S. Duman
Ronald S. Duman Yale University
Elena L. Grigorenko
Elena L. Grigorenko University of Houston
John V. Moran
John V. Moran University of Michigan–Ann Arbor
Jonathan Pevsner
Jonathan Pevsner National Institute of Mental Health
Joseph G. Gleeson
Joseph G. Gleeson University of California, San Diego

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