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Biology and Biochemistry

D-Index
51
Citations
8337
World Ranking
17272
National Ranking
418

Overview

Walter M. van Gulik is affiliated with Delft University of Technology in the Netherlands. Their research encompasses a multidisciplinary approach primarily within the fields of Biochemistry, Genetics and Molecular Biology, as well as Engineering. The scientist has contributed extensively to Molecular Biology, Biomedical Engineering, and Biotechnology, with additional work in Electrical and Electronic Engineering and Spectroscopy.

The research topics covered by Walter M. van Gulik include:

  • Microbial Metabolic Engineering and Bioproduction
  • Biofuel production and bioconversion
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Viral Infectious Diseases and Gene Expression in Insects
  • Enzyme Catalysis and Immobilization
  • Microbial Inactivation Methods
  • Fungal and yeast genetics research

The scientist has published multiple papers across various reputable journals. Notable recent publications are:

  • "Selection and subsequent physiological characterization of industrial Saccharomyces cerevisiae strains during continuous growth at sub- and- supra optimal temperatures," 2020, Biotechnology Reports
  • "Scalable microfluidic droplet on-demand generator for non-steady operation of droplet-based assays," 2020, Lab on a Chip
  • "Mathematical modelling for the optimization of cellulase production using glycerol for cell growth and cellulose as the inducer substrate," 2020, Chemical Engineering Science X
  • "Influence of oxygen concentration on the metabolism of Penicillium chrysogenum," 2022, Engineering in Life Sciences
  • "Predicting the influence of combined oxygen and glucose gradients based on scale-down and modelling approaches for the scale-up of penicillin fermentations," 2022, Process Biochemistry

Frequent collaborators in their work include:

  • Lucas Gelain
  • Luuk A. M. van der Wielen
  • José Geraldo da Cruz Pradella
  • Aline Carvalho da Costa
  • Kartik Totlani

Walter M. van Gulik has contributed research to a variety of journals, with multiple publications appearing in:

  • Fungal Biology
  • Biotechnology Reports
  • Lab on a Chip
  • Engineering in Life Sciences
  • Process Biochemistry

Best Publications

  • Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards.

    Liang Wu;Mlawule R. Mashego;Jan C. van Dam;Angela M. Proell

  • Quantitative evaluation of intracellular metabolite extraction techniques for yeast metabolomics.

    André B. Canelas;Angela ten Pierick;Cor Ras;Reza M. Seifar

  • Role of transcriptional regulation in controlling fluxes in central carbon metabolism of Saccharomyces cerevisiae. A chemostat culture study.

    Pascale Daran-Lapujade;Mickel L.A. Jansen;Jean-Marc Daran;Walter van Gulik

  • The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels.

    Pascale Daran-Lapujade;Sergio Rossell;Walter M. van Gulik;Marijke A. H. Luttik

  • Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of 13C-labeled primary metabolites

    Wouter A. van Winden;Jan C. van Dam;Cor Ras;Roelco J. Kleijn

  • Measuring enzyme activities under standardized in vivo-like conditions for Systems Biology

    Karen van Eunen;Jildau Bouwman;Pascale Daran-Lapujade;Jarne Postmus

  • Validation of a metabolic network for Saccharomyces cerevisiae using mixed substrate studies

    P. A. Vanrolleghem;P. De Jong-Gubbels;W. M. Van Gulik;J. T. Pronk

  • Determination of the cytosolic free NAD/NADH ratio in Saccharomyces cerevisiae under steady‐state and highly dynamic conditions

    André B. Canelas;Walter M. van Gulik;Joseph J. Heijnen

  • Changes in the metabolome of Saccharomyces cerevisiae associated with evolution in aerobic glucose-limited chemostats.

    Mlawule R. Mashego;Mickel L.A. Jansen;Jacobus L. Vinke;Walter M. van Gulik

  • Rapid sampling for analysis of in vivo kinetics using the BioScope: A system for continuous-pulse experiments

    Diana Visser;Gertan A. van Zuylen;Jan C. van Dam;Arthur Oudshoorn

  • An in vivo data-driven framework for classification and quantification of enzyme kinetics and determination of apparent thermodynamic data

    André B. Canelas;Cor Ras;Angela ten Pierick;Walter M. van Gulik

  • Computational fluid dynamics simulation of an industrial P. chrysogenum fermentation with a coupled 9-pool metabolic model : Towards rational scale-down and design optimization

    Cees Haringa;Cees Haringa;Wenjun Tang;Guan Wang;Amit T. Deshmukh

  • Simultaneous quantification of free nucleotides in complex biological samples using ion pair reversed phase liquid chromatography isotope dilution tandem mass spectrometry.

    Reza M. Seifar;Cor Ras;Jan C. van Dam;Walter M. van Gulik

  • In vivo kinetics with rapid perturbation experiments in Saccharomyces cerevisiae using a second-generation BioScope.

    Mlawule R. Mashego;Walter M. van Gulik;Jacobus L. Vinke;Diana Visser

  • Analysis of in vivo kinetics of glycolysis in aerobic Saccharomyces cerevisiae by application of glucose and ethanol pulses.

    Diana Visser;Gertan A. van Zuylen;Jan C. van Dam;Michael R. Eman

  • Atypical Glycolysis in Clostridium thermocellum

    Jilai Zhou;Jilai Zhou;Daniel G. Olson;Daniel G. Olson;D. Aaron Argyros;Yu Deng;Yu Deng

  • A metabolome study of the steady-state relation between central metabolism, amino acid biosynthesis and penicillin production in Penicillium chrysogenum.

    Uly Nasution;Walter M. van Gulik;Cor Ras;Angela Proell

  • Integration of microbial kinetics and fluid dynamics toward model‐driven scale‐up of industrial bioprocesses

    Guan Wang;Wenjun Tang;Jianye Xia;Ju Chu

  • Dynamics of glycolytic regulation during adaptation of Saccharomyces cerevisiae to fermentative metabolism

    Joost van den Brink;André B. Canelas;Walter M. van Gulik;Jack T. Pronk

  • Genome-derived minimal metabolic models for Escherichia coli MG1655 with estimated in vivo respiratory ATP stoichiometry.

    Hilal Taymaz-Nikerel;Amin Espah Borujeni;Peter J.T. Verheijen;Joseph J. Heijnen

Frequent Co-Authors

Joseph J. Heijnen
Joseph J. Heijnen Delft University of Technology
Jack T. Pronk
Jack T. Pronk Delft University of Technology
Wim Soetaert
Wim Soetaert Ghent University
Erick Vandamme
Erick Vandamme Ghent University
Bernard De Baets
Bernard De Baets Ghent University
Peter A. Vanrolleghem
Peter A. Vanrolleghem Université Laval
Lee R. Lynd
Lee R. Lynd Dartmouth College
Jean-Marc Daran
Jean-Marc Daran Delft University of Technology
Robert Verpoorte
Robert Verpoorte Leiden University
Barbara M. Bakker
Barbara M. Bakker University Medical Center Groningen

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