2026 Ursula Jakob: Biology and Biochemistry Researcher – H-Index, Publications & Awards

D-Index & Metrics

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	75	5377	4962	2548	2288	145	18150

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Biology and Biochemistry

5377

4962

2548

2288

145

18150

Biology and Biochemistry

D-Index

Citations

18150

World Ranking

5377

National Ranking

2548

Research.com Recognitions

2020 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ursula Jakob is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans a range of topics within biochemistry, genetics, and molecular biology, contributing significantly to understanding cellular processes and protein biology.

They have contributed extensively to the following main fields of study:

Biochemistry, Genetics and Molecular Biology

The subfields of study where Ursula Jakob has a strong presence include:

Molecular Biology
Genetics
Cell Biology
Aging
Neurology

Their main research topics center around:

Heat shock proteins research
Coagulation, Bradykinin, Polyphosphates, and Angioedema
Endoplasmic Reticulum Stress and Disease
Genetics, Aging, and Longevity in Model Organisms
Redox biology and oxidative stress
Parkinson's Disease Mechanisms and Treatments
Enzyme Structure and Function

Ursula Jakob has published numerous papers in prominent venues, with frequent publications in the following journals:

Journal of Biological Chemistry
bioRxiv (Cold Spring Harbor Laboratory)
mBio
Nature Reviews Molecular Cell Biology
Molecular Cell

Recent notable papers include:

"Fundamentals of redox regulation in biology," 2024, Nature Reviews Molecular Cell Biology
"Copper Induces Protein Aggregation, a Toxic Process Compensated by Molecular Chaperones," 2022, mBio
"Polyphosphate drives bacterial heterochromatin formation," 2021, Science Advances
"Polyphosphate Functions In Vivo as an Iron Chelator and Fenton Reaction Inhibitor," 2020, mBio
"Depletion of mitochondrial inorganic polyphosphate (polyP) in mammalian cells causes metabolic shift from oxidative phosphorylation to glycolysis," 2021, Biochemical Journal

The scientist has collaborated extensively with several researchers including:

Lila M. Gierasch
F. Peter Guengerich
Ruma Banerjee
Roger Colbran
Peter Cresswell

Ursula Jakob's work has been recognized with memberships and fellowships including:

German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften (2020) for Biochemistry and Biophysics
Fellow of the American Association for the Advancement of Science (AAAS) (2020)

Best Publications

Small heat shock proteins are molecular chaperones

U Jakob;M Gaestel;K Engel;J Buchner

1715
Citations
Hsp90 chaperones protein folding in vitro.

Hans Wiech;Johannes Buchner;Richard Zimmermann;Ursula Jakob

668
Citations
Chaperone Activity with a Redox Switch

Ursula Jakob;Wilson B Muse;Markus Eser;James C.A. Bardwell

630
Citations
Quantifying changes in the thiol redox proteome upon oxidative stress in vivo

Lars I. Leichert;Florian Gehrke;Harini V. Gudiseva;Tom Blackwell

583
Citations
Assisting spontaneity: the role of Hsp90 and small Hsps as molecular chaperones

Ursula Jakob;Johannes Buchner

522
Citations
Transient Interaction of Hsp90 with Early Unfolding Intermediates of Citrate Synthase: IMPLICATIONS FOR HEAT SHOCK IN VIVO

Ursula Jakob;Hauke Lilie;Ines Meyer;Johannes Buchner

467
Citations
Bacterial Responses to Reactive Chlorine Species

Michael J. Gray;Wei Yun Wholey;Ursula Jakob

448
Citations
Oxidant Sensing by Reversible Disulfide Bond Formation

Claudia M. Cremers;Ursula Jakob

446
Citations
Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding

J. Winter;M. Ilbert;P.C.F. Graf;D. Özcelik

437
Citations
Thiol-based redox switches in eukaryotic proteins.

Nicolas Brandes;Sebastian Schmitt;Ursula Jakob

418
Citations
The role of thiols in antioxidant systems.

Kathrin Ulrich;Ursula Jakob

403
Citations
Polyphosphate Is a Primordial Chaperone

Michael J. Gray;Wei Yun Wholey;Nico O. Wagner;Claudia M. Cremers

344
Citations
RNA methylation under heat shock control

Hans Bügl;Eric B. Fauman;Bart L. Staker;Fuzhong Zheng

297
Citations
Protein thiol modifications visualized in vivo.

Lars I Leichert;Ursula Jakob

292
Citations
Analysis of chaperone function using citrate synthase as nonnative substrate protein.

Johannes Buchner;Holger Grallert;Ursula Jakob

276
Citations
Thiol-based redox switches

Bastian Groitl;Ursula Jakob

242
Citations
XIAP Is a Copper Binding Protein Deregulated in Wilson's Disease and Other Copper Toxicosis Disorders

Arjmand R. Mufti;Ezra Burstein;Ezra Burstein;Rebecca A. Csomos;Paul C.F. Graf

228
Citations
Redox Switch of Hsp33 Has a Novel Zinc-binding Motif

Ursula Jakob;Markus Eser;James C.A. Bardwell

225
Citations
Severe Oxidative Stress Causes Inactivation of DnaK and Activation of the Redox-Regulated Chaperone Hsp33

Jeannette Winter;Katrin Linke;Anna Jatzek;Ursula Jakob

205
Citations
Genetic selection designed to stabilize proteins uncovers a chaperone called Spy

Shu Quan;Philipp Koldewey;Philipp Koldewey;Tim Tapley;Tim Tapley;Nadine Kirsch;Nadine Kirsch

194
Citations