Therese Wiedmer

Overview

Best Publications

• Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity.

  P J Sims;E M Faioni;T Wiedmer;S J Shattil

  921
  Citations

• Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane. Studies in Scott syndrome: an isolated defect in platelet procoagulant activity.

  P J Sims;T Wiedmer;C T Esmon;H J Weiss

  848
  Citations

• Molecular Cloning of Human Plasma Membrane Phospholipid Scramblase: A PROTEIN MEDIATING TRANSBILAYER MOVEMENT OF PLASMA MEMBRANE PHOSPHOLIPIDS *

  Quansheng Zhou;Ji Zhao;James G. Stout;Robert A. Luhm

  513
  Citations

• Isolation of an Erythrocyte Membrane Protein that Mediates Ca2+-dependent Transbilayer Movement of Phospholipid

  Fran¸ois Bassé;James G. Stout;Peter J. Sims;Therese Wiedmer

  352
  Citations

• Platelet-derived microparticles express high affinity receptors for factor VIII.

  G E Gilbert;P J Sims;T Wiedmer;B Furie

  343
  Citations

• Unraveling the mysteries of phospholipid scrambling.

  Peter J. Sims;Therese Wiedmer

  293
  Citations

• Complement-Induced Vesiculation and Exposure of Membrane Prothrombinase Sites in Platelets of Paroxysmal Nocturnal Hemoglobinuria

  T Wiedmer;SE Hall;TL Ortel;WH Kane

  277
  Citations

• Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1

  Quansheng Zhou;J.i. Zhao;Therese Wiedmer;Peter J. Sims

  266
  Citations

• Level of Expression of Phospholipid Scramblase Regulates Induced Movement of Phosphatidylserine to the Cell Surface

  Ji Zhao;Quansheng Zhou;Therese Wiedmer;Peter J. Sims

  260
  Citations

• Sphingomyelin Hydrolysis to Ceramide during the Execution Phase of Apoptosis Results from Phospholipid Scrambling and Alters Cell-Surface Morphology

  Annemiek D. Tepper;Paula Ruurs;Therese Wiedmer;Peter J. Sims

  249
  Citations

• Complement proteins C5b-9 stimulate procoagulant activity through platelet prothrombinase.

  Therese Wiedmer;Charles T. Esmon;Peter J. Sims

  248
  Citations

• Inhibition of the complement membrane attack complex by the galactose-specific adhesion of Entamoeba histolytica.

  L L Braga;H Ninomiya;J J McCoy;S Eacker

  243
  Citations

• Role of calcium and calpain in complement-induced vesiculation of the platelet plasma membrane and in the exposure of the platelet factor Va receptor.

  Therese Wiedmer;Sanford J. Shattil;Michael Cunningham;Peter J. Sims

  242
  Citations

• The response of human platelets to activated components of the complement system

  Peter J Sims;Therese Wiedmer

  237
  Citations

• Identification of three new members of the phospholipid scramblase gene family.

  Therese Wiedmer;Quansheng Zhou;Deborah Y. Kwoh;Peter J. Sims

  210
  Citations

• Defective Ca(2+)-induced microvesiculation and deficient expression of procoagulant activity in erythrocytes from a patient with a bleeding disorder: a study of the red blood cells of Scott syndrome

  Edouard M. Bevers;Therese Wiedmer;Paul Comfurius;Sanford J. Shattil

  207
  Citations

• Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression.

  Bengt Fadeel;Bettina Gleiss;Kari Högstrand;Joya Chandra

  205
  Citations

• Contribution of platelet microparticle formation and granule secretion to the transmembrane migration of phosphatidylserine.

  Chi-Pei Chang;Ji Zhao;T. Wiedmer;P. J. Sims

  203
  Citations

• Caspase-Independent Exposure of Aminophospholipids and Tyrosine Phosphorylation in Bicarbonate Responsive Human Sperm Cells

  K.J. de Vries;T. Wiedmer;P.J. Sims;B.M. Gadella

  174
  Citations

• Regulatory control of complement on blood platelets. Modulation of platelet procoagulant responses by a membrane inhibitor of the C5b-9 complex.

  P J Sims;S A Rollins;S A Rollins;T Wiedmer;T Wiedmer

  161
  Citations