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D-Index & Metrics

Neuroscience

D-Index
70
Citations
19597
World Ranking
2500
National Ranking
1186

Research.com Recognitions

  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Synthia H. Mellon is affiliated with the University of California, San Francisco in the United States. Their research spans multiple disciplines within neuroscience and medicine, focusing particularly on behavioral neuroscience, developmental neuroscience, physiology, molecular biology, and biological psychiatry.

The primary fields of study for this scientist are:

  • Neuroscience
  • Medicine

Their work delves into various subfields, including:

  • Behavioral Neuroscience
  • Developmental Neuroscience
  • Physiology
  • Molecular Biology
  • Biological Psychiatry

Among the main topics addressed in their research are:

  • Stress Responses and Cortisol
  • Anesthesia and Neurotoxicity Research
  • Tryptophan and brain disorders
  • Posttraumatic Stress Disorder Research
  • Epigenetics and DNA Methylation
  • Birth, Development, and Health
  • Spaceflight effects on biology

Synthia H. Mellon has published extensively in several key journals. Frequent publication venues include:

  • Molecular Psychiatry
  • Translational Psychiatry
  • Biological Psychiatry
  • Journal of Affective Disorders
  • Psychoneuroendocrinology

Several recent papers provide insight into their research focus:

  • "Pre-deployment risk factors for PTSD in active-duty personnel deployed to Afghanistan: a machine-learning approach for analyzing multivariate predictors" (2020), Molecular Psychiatry
  • "A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD" (2020), Molecular Psychiatry
  • ""GrimAge," an epigenetic predictor of mortality, is accelerated in major depressive disorder" (2021), Translational Psychiatry
  • "Abnormal levels of mitochondrial proteins in plasma neuronal extracellular vesicles in major depressive disorder" (2021), Molecular Psychiatry
  • "Role of enhanced glucocorticoid receptor sensitivity in inflammation in PTSD: insights from computational model for circadian-neuroendocrine-immune interactions" (2020), American Journal of Physiology-Endocrinology and Metabolism

Frequent collaborators of Mellon include:

  • Owen M. Wolkowitz
  • Marti Jett
  • Rasha Hammamieh
  • Victor I. Reus
  • Charles R. Marmar

In recognition of their contributions, Mellon was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2005.

Best Publications

  • Neurosteroids: Biosynthesis and Function of These Novel Neuromodulators

    Nathalie A. Compagnone;Synthia H. Mellon

  • Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS).

    Nicole Maninger;Owen M. Wolkowitz;Victor I. Reus;Elissa S. Epel

  • Neurosteroids: biochemistry and clinical significance

    Synthia H Mellon;Lisa D Griffin

  • Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone.

    Lisa D Griffin;Wenhui Gong;Lucie Verot;Synthia H Mellon

  • Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

    Lisa D. Griffin;Synthia H. Mellon

  • Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.

    Owen M. Wolkowitz;Synthia H. Mellon;Elissa S. Epel;Jue Lin

  • Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance.

    Jue Lin;Elissa Epel;Joshua Cheon;Candyce Kroenke

  • Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain.

    Synthia H. Mellon;Christian F. Deschepper

  • Oxidative stress, inflammation and treatment response in major depression

    Daniel Lindqvist;Daniel Lindqvist;Firdaus S. Dhabhar;S. Jill James;Christina M. Hough

  • A culture system to study oligodendrocyte myelination processes using engineered nanofibers

    Seonok Lee;Michelle K. Leach;Stephanie A. Redmond;S. Y Christin Chong

  • Dehydroepiandrosterone: A potential signalling molecule for neocortical organization during development

    Nathalie A. Compagnone;Synthia H. Mellon

  • Biosynthesis and action of neurosteroids.

    Synthia H Mellon;Lisa D Griffin;Nathalie A Compagnone

  • Molecular mechanism of suppression of testicular steroidogenesis by proinflammatory cytokine tumor necrosis factor alpha.

    Cheol Yi Hong;Jin Hee Park;Ryun Seop Ahn;Suhn Young Im

  • Neurosteroids: biochemistry, modes of action, and clinical relevance.

    S H Mellon

  • Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells.

    S R Spindler;S H Mellon;J D Baxter

  • Depression gets old fast: do stress and depression accelerate cell aging?

    Owen M. Wolkowitz;Elissa S. Epel;Victor I. Reus;Synthia H. Mellon

  • Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B

    James Bristow;Meng Kian Tee;Stephen E. Gitelman;Synthia H. Mellon

  • Analysis by immunocytochemistry and in situ hybridization of renin and its mRNA in kidney, testis, adrenal, and pituitary of the rat.

    Christian F. Deschepper;Synthia H. Mellon;Frederic Cumin;John D. Baxter

  • Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging.

    Daniel Lindqvist;Elissa S. Epel;Synthia H. Mellon;Brenda W. Penninx

  • Biosynthesis of neurosteroids and regulation of their synthesis.

    Synthia H Mellon;Hubert Vaudry

Frequent Co-Authors

Elissa S. Epel
Elissa S. Epel University of California, San Francisco
Rachel Yehuda
Rachel Yehuda United States Department of Veterans Affairs
Janine D. Flory
Janine D. Flory Icahn School of Medicine at Mount Sinai
Elizabeth H. Blackburn
Elizabeth H. Blackburn University of California, San Francisco
Susanne G. Mueller
Susanne G. Mueller University of California, San Francisco
Leroy Hood
Leroy Hood University of Washington
Kerry J. Ressler
Kerry J. Ressler Harvard University
Thomas C. Neylan
Thomas C. Neylan University of California, San Francisco
Michael W. Weiner
Michael W. Weiner University of California, San Francisco

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Related Online Degrees & Career Pathways

Studying neuroscience in the USA opens doors to a variety of related online degrees and careers in mental health, psychology, and therapy. With a background in neuroscience, you may find rewarding opportunities in the counseling and behavioral health fields, where understanding brain function is highly valued.

Those interested in clinical practice or counseling may explore cacrep accredited degrees, which ensure programs meet high professional standards. If you are considering flexible study options, check out online mental health degree programs that can lead to careers such as mental health counselors or case managers.

For those drawn to family dynamics and therapy, an marriage and family therapist degree can expand your career possibilities. Additionally, pursuing an advanced credential like an affordable online masters in clinical psychology can prepare you for clinical roles or further research opportunities.

Each pathway leverages your neuroscience background and can be pursued online, making them accessible for students balancing work or other commitments.

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