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D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
5655
World Ranking
19330
National Ranking
1316

Overview

Robert Seckler is affiliated with the University of Potsdam in Germany and focuses their research primarily in the fields of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields including Molecular Biology, Cellular and Molecular Neuroscience, Oncology, Biotechnology, and Organic Chemistry.

Their research topics include Glycosylation and Glycoproteins Research, Neuropeptides and Animal Physiology, Receptor Mechanisms and Signaling, Peptidase Inhibition and Analysis, Biochemical and Structural Characterization, Chemical Synthesis and Analysis, and Enzyme Production and Characterization.

Seckler has published multiple papers in notable scientific venues. Some of the recent publications include:

  • Self-Assembly of Exendin-4-Derived Dual Peptide Agonists is Mediated by Acylation and Correlated to the Length of Conjugated Fatty Acyl Chains, 2020, Molecular Pharmaceutics
  • A Conserved Hydrophobic Moiety and Helix-Helix Interactions Drive the Self-Assembly of the Incretin Analog Exendin-4, 2021, Biomolecules
  • Self-Competitive Inhibition of the Bacteriophage P22 Tailspike Endorhamnosidase by O-Antigen Oligosaccharides, 2020, Biochemistry
  • Portal = Sommer an der Uni: Leere Hörsäle? Volle Terminkalender!, 2020, publish.UP (University of Potsdam)

Frequent co-authors in their publications include Martin Wolff, Anja Schüler, Klaus Gast, Andreas Evers, and Stefania Pfeiffer-Marek, each appearing in multiple collaborations.

The publication venues where Seckler's work appears frequently are:

  • Molecular Pharmaceutics
  • Biomolecules
  • Biochemistry
  • publish.UP (University of Potsdam)

Best Publications

  • Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer.

    Stefan Steinbacher;Robert Seckler;Stefan Miller;Boris Steipe

  • Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors

    Stefan Steinbacher;Ulrich Baxa;Stefan Miller;Andrej Weintraub

  • Mapping protein collapse with single-molecule fluorescence and kinetic synchrotron radiation circular dichroism spectroscopy

    Armin S. Hoffmann;Avinash S. Kane;Daniel Nettels;David E. Hertzog

  • Phage P22 tailspike protein: crystal structure of the head-binding domain at 2.3 A, fully refined structure of the endorhamnosidase at 1.56 A resolution, and the molecular basis of O-antigen recognition and cleavage.

    Stefan Steinbacher;Stefan Miller;Ulrich Baxa;Nediljko Budisa

  • Protein Misassembly IN VITRO

    Rainer Jaenicke;Robert Seckler

  • Crystal structure of Escherichia coli phage HK620 tailspike: podoviral tailspike endoglycosidase modules are evolutionarily related.

    Stefanie Barbirz;Jürgen J. Müller;Charlotte Uetrecht;Alvin J. Clark

  • Molecular aspects of sugar:ion cotransport.

    J. Keith Wright;Robert Seckler;Peter Overath

  • Protein folding and protein refolding.

    Robert Seckler;Rainer Jaenicke

  • Interactions of phage P22 tails with their cellular receptor, Salmonella O-antigen polysaccharide

    U. Baxa;S. Steinbacher;S. Miller;A. Weintraub

  • Structure of the Receptor-Binding Protein of Bacteriophage Det7: a Podoviral Tail Spike in a Myovirus

    Monika Walter;Christian Fiedler;Renate Grassl;Manfred Biebl

  • Tailspike Interactions with Lipopolysaccharide Effect DNA Ejection from Phage P22 Particles in Vitro

    Dorothee Andres;Christin Hanke;Ulrich Baxa;Anaït Seul

  • Peptide-specific antibody locates the COOH terminus of the lactose carrier of Escherichia coli on the cytoplasmic side of the plasma membrane.

    R Seckler;J K Wright;P Overath

  • In vitro folding pathway of phage P22 tailspike protein.

    Albert Fuchs;Claudia Seiderer;Robert Seckler

  • Bacterial protein disulfide isomerase: efficient catalysis of oxidative protein folding at acidic pH.

    Martina Wunderlich;Angelika Otto;Robert Seckler;Rudi Glockshuber

  • Interaction of two intrinsically disordered plant stress proteins (COR15A and COR15B) with lipid membranes in the dry state

    Anja Thalhammer;Michaela Hundertmark;Antoaneta V. Popova;Robert Seckler

  • An Intersubunit Active Site between Supercoiled Parallel Beta Helices in the Trimeric Tailspike Endorhamnosidase of Shigella Flexneri Phage Sf6.

    Jürgen J. Müller;Stefanie Barbirz;Karolin Heinle;Alexander Freiberg

  • Reconstitution of the thermostable trimeric phage P22 tailspike protein from denatured chains in vitro.

    R Seckler;A Fuchs;J King;R Jaenicke

  • Efficient refolding of aggregation-prone citrate synthase by polyol osmolytes: how well are protein folding and stability aspects coupled?

    Rajesh Mishra;Robert Seckler;Rajiv Bhat

  • Efficient Catalysis of Disulfide Formation During Protein Folding with a Single Active-site Cysteine

    Martina Wunderlich;Martina Wunderlich;Angelika Otto;Angelika Otto;Klaus Maskos;Klaus Maskos;Matthias Mü;Matthias Mü

  • Interactions of phage P22 tailspike protein with GroE molecular chaperones during refolding in vitro.

    R Brunschier;M Danner;R Seckler

Frequent Co-Authors

Ulrich Baxa
Ulrich Baxa Leidos (United States)
Udo Heinemann
Udo Heinemann Max Delbrück Center for Molecular Medicine
Benjamin Schuler
Benjamin Schuler University of Zurich
Robert Huber
Robert Huber University of Duisburg-Essen
Peter Overath
Peter Overath Max Planck Society
Rainer Jaenicke
Rainer Jaenicke University of Regensburg
Dirk K. Hincha
Dirk K. Hincha Max Planck Society
Alexander N. Freiberg
Alexander N. Freiberg The University of Texas Medical Branch at Galveston
David A. Horsley
David A. Horsley University of California, Davis

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