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Neuroscience

D-Index
36
Citations
5004
World Ranking
9027
National Ranking
2

Overview

Nayef E. Saadé is affiliated with the American University of Beirut in Lebanon. Their research spans primarily the field of Neuroscience, with a focus on developmental neuroscience, neurology, and cellular and molecular neuroscience. Their work addresses topics including neurogenesis and neuroplasticity mechanisms, neurological disorders and treatments, and cognitive neuroscience.

The scientist has contributed to a range of recent publications that explore various aspects of hippocampal neurogenesis and neural mechanisms. Selected recent papers include:

  • Long-term stimulation of the anteromedial thalamus increases hippocampal neurogenesis and spatial reference memory in adult rats, 2021, Behavioural Brain Research
  • Urinary Tract Infections Impair Adult Hippocampal Neurogenesis, 2022, Biology
  • Sustained Activation of the Anterior Thalamic Neurons with Low Doses of Kainic Acid Boosts Hippocampal Neurogenesis, 2022, Cells
  • Santé intime et intelligence artificielle: enquête sur l'usage des chatbots de santé chez les femmes libanaises, 2025, Progrès en Urologie - FMC
  • Entre gêne et accessibilité: recours aux agents conversationnels basés sur l'IA pour la santé intime des jeunes hommes au Liban, 2025, Progrès en Urologie - FMC

Nayef E. Saadé frequently collaborates with other researchers in related fields. Common coauthors include:

  • Farah Chamaa
  • Batoul Darwish
  • Wassim Abou-Kheir
  • Ziad Nahas
  • Elie D. Al-Chaer

The publication venues where they have most often contributed include:

  • Progrès en Urologie - FMC
  • Behavioural Brain Research
  • Biology
  • Cells

Nayef E. Saadé's research topics encompass a variety of specialized areas within neuroscience and neuropharmacology, such as:

  • Neurogenesis and neuroplasticity mechanisms
  • Neurological disorders and treatments
  • Transcranial Magnetic Stimulation Studies
  • Congenital gastrointestinal and neural anomalies
  • Cerebrospinal fluid and hydrocephalus
  • Memory and Neural Mechanisms
  • Neuroscience and Neuropharmacology Research

Their work integrates studies on memory and spatial reference, neural stimulation techniques, and the effects of peripheral conditions on brain neurogenesis. This profile reflects a multi-disciplinary approach combining basic neuroscience research with clinical applications and emerging technologies such as artificial intelligence in health contexts.

Best Publications

  • Cytokines and neuro-immune-endocrine interactions: a role for the hypothalamic-pituitary-adrenal revolving axis.

    John J Haddad;Nayef E Saadé;Bared Safieh-Garabedian

  • Endotoxin-induced local inflammation and hyperalgesia in rats and mice: a new model for inflammatory pain.

    Salim A Kanaan;Nayef E Saadé;John J Haddad;Alexander M Abdelnoor

  • Augmentation of nociceptive reflexes and chronic deafferentation pain by chemical lesions of either dopaminergic terminals or midbrain dopaminergic neurons.

    Nayef E Saadé;Samir F Atweh;Nadia B Bahuth;Suhayl J Jabbur

  • Nociceptive behavior in animal models for peripheral neuropathy: spinal and supraspinal mechanisms.

    Nayef E. Saadé;Suhayl J. Jabbur

  • Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.

    J. Barchini;S. Tchachaghian;F. Shamaa;S.J. Jabbur

  • Attenuation of neuropathic pain by segmental and supraspinal activation of the dorsal column system in awake rats

    C El-Khoury;N Hawwa;M Baliki;S.F Atweh

  • Interleukin-10 and the regulation of mitogen-activated protein kinases: are these signalling modules targets for the anti-inflammatory action of this cytokine?

    John J Haddad;Nayef E Saadé;Bared Safieh-Garabedian

  • Alpha-melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kappaB translocation and activation: evidence for involvement of an interleukin-1beta193-195 receptor antagonism in the alveolar epithelium.

    John J. E. Haddad;Ryszard Lauterbach;Nayef E. Saadé;Bared Safieh-Garabedian

  • The role of the sympathetic efferents in endotoxin-induced localized inflammatory hyperalgesia and cytokine upregulation

    B. Safieh-Garabedian;S Poole;J.J. Haddad;C.A. Massaad

  • Chemioxyexcitation (delta pO2/ROS)-dependent release of IL-1 beta, IL-6 and TNF-alpha: evidence of cytokines as oxygen-sensitive mediators in the alveolar epithelium.

    John J.E. Haddad;Bared Safieh-Garabedian;Nayef E. Saadé;Salim A. Kanaan

  • Involvement of substance P, CGRP and histamine in the hyperalgesia and cytokine upregulation induced by intraplantar injection of capsaicin in rats.

    C.A Massaad;B Safieh-Garabedian;S Poole;S.F Atweh

  • Upregulation of proinflammatory cytokines and nerve growth factor by intraplantar injection of capsaicin in rats.

    N. E. Saadé;C. A. Massaad;C. I. Ochoa‐Chaar;S. J. Jabbur

  • Supraspinal modulation of nociception in awake rats by stimulation of the dorsal column nuclei.

    Nayef E. Saade;Munther S. Tabet;Shawke A. Soueidan;Mona Bitar

  • Interleukin-10 reduces the endotoxin-induced hyperalgesia in mice.

    Salim A Kanaan;Stephen Poole;Nayef E Saadé;Suhayl Jabbur

  • Nociceptive behaviour induced by dental application of irritants to rat incisors: A new model for tooth inflammatory pain

    José-Johann Chidiac;Khaldoun Rifai;Nadim N Hawwa;Cynthia A Massaad

  • Up-regulation of nerve growth factor and interleukin-10 in inflamed and non-inflamed intestinal segments in rats with experimental colitis.

    Kassem A. Barada;Fadi H. Mourad;Sarah I. Sawah;Carmen Khoury

  • Chronic dizocilpine or apomorphine and development of neuropathy in two animal models II: effects on brain cytokines and neurotrophins.

    Hassen Al-Amin;Rani Sarkis;Samir Atweh;Suhayl Jabbur

  • Modulation of ultraviolet-induced hyperalgesia and cytokine upregulation by interleukins 10 and 13

    Nayef E Saadé;Isam W Nasr;Cynthia A Massaad;Bared Safieh-Garabedian

  • Inhibition of nociceptive evoked activity in spinal neurons through a dorsal column-brainstem-spinal loop.

    Nayef E. Saadé;Munther S. Tabet;Nabil R. Banna;Samir F. Atweh

  • Attenuation of neuropathic manifestations by local block of the activities of the ventrolateral orbito-frontal area in the rat.

    M Baliki;H.A Al-Amin;SF Atweh;M Jaber

Frequent Co-Authors

Mireille Dardenne
Mireille Dardenne Centre national de la recherche scientifique, CNRS
Mohamed Jaber
Mohamed Jaber University of Poitiers
Marwan N. Baliki
Marwan N. Baliki Northwestern University
Björn A. Meyerson
Björn A. Meyerson Karolinska Institute
Patrick D. Wall
Patrick D. Wall University College London
Bengt Linderoth
Bengt Linderoth Karolinska Institute
Carl Y. Saab
Carl Y. Saab Cleveland Clinic
Luis Garcia-Larrea
Luis Garcia-Larrea Claude Bernard University Lyon 1
Alain Privat
Alain Privat Grenoble Alpes University
Daniel Le Bars
Daniel Le Bars Sorbonne University

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