Mikael Simons

Best Publications

• Microglia states and nomenclature: A field at its crossroads

  Unknown

  2095
  Citations

• Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity.

  Ludovico Cantuti-Castelvetri;Ludovico Cantuti-Castelvetri;Ravi Ojha;Liliana D. Pedro;Liliana D. Pedro;Minou Djannatian;Minou Djannatian

  1905
  Citations

• Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons.

  Mikael Simons;Patrick Keller;Bart De Strooper;Konrad Beyreuther

  1553
  Citations

• Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

  K. Fassbender;M. Simons;C. Bergmann;M. Stroick

  1497
  Citations

• Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

  Carsten Frühbeis;Dominik Fröhlich;Wen Ping Kuo;Jesa Amphornrat

  949
  Citations

• Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

  Dirk Fitzner;Dirk Fitzner;Mareike Schnaars;Denise van Rossum;Gurumoorthy Krishnamoorthy

  912
  Citations

• Oligodendrocytes: Myelination and Axonal Support

  Mikael Simons;Klaus Armin Nave

  884
  Citations

• Cell type- and brain region-resolved mouse brain proteome

  Kirti Sharma;Sebastian Schmitt;Sebastian Schmitt;Caroline G Bergner;Caroline G Bergner;Stefka Tyanova

  868
  Citations

• Myelin in the Central Nervous System: Structure, Function, and Pathology.

  Christine Stadelmann;Sebastian Timmler;Alonso Barrantes-Freer;Mikael Simons

  703
  Citations

• Age-related myelin degradation burdens the clearance function of microglia during aging

  Shima Safaiyan;Nirmal Kannaiyan;Nicolas Snaidero;Nicolas Snaidero;Simone Brioschi

  606
  Citations

• Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial.

  Mikael Simons;Frank Schwärzler;Dieter Lütjohann;Klaus Von Bergmann

  578
  Citations

• Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

  Nicolas Snaidero;Wiebke Möbius;Tim Czopka;Liesbeth H.P. Hekking

  489
  Citations

• White matter aging drives microglial diversity.

  Shima Safaiyan;Simon Besson-Girard;Tuğberk Kaya;Ludovico Cantuti-Castelvetri;Ludovico Cantuti-Castelvetri

  447
  Citations

• Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

  Unknown

  425
  Citations

• Cholesterol and Alzheimer's disease: is there a link?

  Mikael Simons;Patrick Keller;Johannes Dichgans;Jörg B. Schulz

  366
  Citations

• Central nervous system myelin: structure, synthesis and assembly

  Shweta Aggarwal;Larisa Yurlova;Mikael Simons;Mikael Simons

  350
  Citations

• Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions

  Eugenio F. Fornasiero;Sunit Mandad;Sunit Mandad;Hanna Wildhagen;Mihai Alevra

  344
  Citations

• Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.

  Kai Schlepckow;Kathryn M Monroe;Gernot Kleinberger;Ludovico Cantuti-Castelvetri

  341
  Citations

• Efficient Inhibition of the Alzheimer's Disease β-Secretase by Membrane Targeting

  Lawrence Rajendran;Anja Schneider;Georg Schlechtingen;Sebastian Weidlich

  326
  Citations

• Metabolism and functions of lipids in myelin.

  Sebastian Schmitt;Ludovici Cantuti Castelvetri;Mikael Simons

  315
  Citations