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Biology and Biochemistry

D-Index
57
Citations
25777
World Ranking
13517
National Ranking
1055

Overview

Stephen Newhouse is affiliated with King's College London in the United Kingdom. Their research work primarily falls within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a notable focus on Neurology and Molecular Biology as key subfields. Other subfields in their work include Genetics, Physiology, and Psychiatry and Mental Health.

The scientist's research topics cover multiple areas, including Epigenetics and DNA Methylation, Genetic Associations and Epidemiology, Amyotrophic Lateral Sclerosis Research, Alzheimer's Disease Research and Treatments, Bioinformatics and Genomic Networks, Dementia and Cognitive Impairment Research, and Biochemical Acid Research Studies.

Stephen Newhouse has contributed to scientific literature with several recent publications, which include the following:

  • "An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene", 2020, Neurobiology of Aging
  • "Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics", 2020, Cell Reports
  • "Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways", 2020, Alzheimer's & Dementia
  • "Working Towards a Blood-Derived Gene Expression Biomarker Specific for Alzheimer's Disease", 2020, Journal of Alzheimer's Disease
  • "A recessive S174X mutation in Optineurin causes amyotrophic lateral sclerosis through a loss of function via allele-specific nonsense-mediated decay", 2021, Neurobiology of Aging

The scientist has frequently published in venues such as Neurobiology of Aging, UNC Libraries, Cell Reports, Alzheimer's & Dementia, and the Journal of Alzheimer's Disease.

Stephen Newhouse frequently collaborates with other researchers. Their notable coauthors include Richard Dobson, Simon Lovestone, Robert C. Green, Petroula Proitsi, and Angela Hodges, reflecting ongoing collaborative work within their research community.

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia

    Chris Wallace;Stephen J. Newhouse;Peter Braund;Feng Zhang

  • Genome-wide mapping of human loci for essential hypertension

    M Caulfield;P Munroe;J Pembroke;N Samani

  • Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

    Dan E. Arking;Sara L. Pulit;Sara L. Pulit;Sara L. Pulit;Lia Crotti;Pim Van Der Harst

  • Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

    Folkert W. Asselbergs;Yiran Guo;Yiran Guo;Erik P A Van Iperen;Suthesh Sivapalaratnam

  • Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

    Richa Saxena;Richa Saxena;Clara C. Elbers;Clara C. Elbers;Yiran Guo;Inga Peter

  • The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder.

    Bradley N. Smith;Stephen Newhouse;Aleksey Shatunov;Caroline Vance

  • Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study

    Aleksey Shatunov;Kin Mok;Stephen Newhouse;Michael E Weale

  • Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.

    Martina Sattlecker;Martina Sattlecker;Steven J. Kiddle;Steven J. Kiddle;Stephen Newhouse;Stephen Newhouse;Petroula Proitsi;Petroula Proitsi

  • An examination of polygenic score risk prediction in individuals with first-episode psychosis

    Evangelos Vassos;Marta Di Forti;Jonathan Coleman;Conrad Iyegbe

  • Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

    Elin Org;Susana Eyheramendy;Peeter Juhanson;Christian Gieger

  • Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

    Philippa J. Talmud;Fotios Drenos;Sonia Shah;Tina Shah

  • Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study.

    Steven J. Kiddle;Martina Sattlecker;Petroula Proitsi;Andrew Simmons

  • Multi-polygenic score approach to trait prediction

    E Krapohl;H Patel;H Patel;S Newhouse;S Newhouse;S Newhouse;C J Curtis

  • Microarray, qPCR, and KCNJ5 Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors

    Elena A. B. Azizan;Brian Y. H. Lam;Stephen J. Newhouse;Junhua Zhou

Frequent Co-Authors

Mark J. Caulfield
Mark J. Caulfield Queen Mary University of London
Gerome Breen
Gerome Breen King's College London
Patricia B. Munroe
Patricia B. Munroe Queen Mary University of London
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Simon Lovestone
Simon Lovestone University of Oxford
Martin Farrall
Martin Farrall University of Oxford
Anna F. Dominiczak
Anna F. Dominiczak University of Glasgow
Cathryn M. Lewis
Cathryn M. Lewis King's College London
Morris J. Brown
Morris J. Brown Queen Mary University of London
John M. C. Connell
John M. C. Connell University of Dundee

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