World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
43
Citations
9917
World Ranking
19360
National Ranking
7903

Overview

Malcolm J. Fraser is affiliated with the University of Notre Dame in the United States. Their research spans multiple areas within medicine, with a focus on both broad and specialized subfields including Public Health, Environmental and Occupational Health, Hepatology, Biomaterials, Molecular Biology, and Microbiology.

The scientist's work encompasses key topics such as mosquito-borne diseases and control, Hepatitis C virus research, silk-based biomaterials and applications, RNA interference and gene delivery, antimicrobial peptides and activities, insect symbiosis and bacterial influences, and invertebrate immune response mechanisms.

Among recent publications by Fraser are:

  • "Marjory Florence Foyle" (2025) published in BMJ
  • "Effective Suppression of Chikungunya Virus Infection in Cell Cultures using Hepatitis Delta Ribozymes" (2024) published in Preprints.org
  • "Design and testing of Hepatitis Delta Ribozymes for suppression of Chikungunya virus infection in cell cultures" (2024) published in Medical Research Archives
  • "Maxizyme-mediated suppression of chikungunya virus replication and transmission in transgenic Aedes aegypti mosquitoes" (2023) published in Frontiers in Microbiology
  • "Transgenic and Diet-Enhanced Silk Production for Reinforced Biomaterials: A Metamaterial Perspective" (2020) published in Annual Review of Biomedical Engineering

Frequent collaborators include Mark E Fraser, Cheryl Kucharski, Zoe Loh, Erin Hanahoe, and Jung Woo Leem.

Publications are distributed across several notable venues such as Annual Review of Biomedical Engineering, Frontiers in Microbiology, Preprints.org, Medical Research Archives, and BMJ.

Best Publications

  • Production of human beta interferon in insect cells infected with a baculovirus expression vector.

    G E Smith;M D Summers;M J Fraser

  • Germline transformation of the silkworm Bombyx mori L. using a piggyBac transposon-derived vector

    Toshiki Tamura;Chantal Thibert;Corinne Royer;Toshio Kanda

  • Transposon mutagenesis of baculoviruses: analysis of Trichoplusia ni transposon IFP2 insertions within the FP-locus of nuclear polyhedrosis viruses.

    Lynne Csiszar Cary;Michael Goebel;Bartholomew G. Corsaro;Hwei Gene Wang

  • Molecular Engineering of the Autographa californica Nuclear Polyhedrosis Virus Genome: Deletion Mutations Within the Polyhedrin Gene

    Gale E. Smith;M. J. Fraser;Max D. Summers

  • Precise excision of TTAA-specific lepidopteran transposons piggyBac (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera.

    Fraser Mj;Ciszczon T;Elick T;Bauser C

  • Acquisition of Host Cell DNA Sequences by Baculoviruses: Relationship Between Host DNA Insertions and FP Mutants of Autographa californica and Galleria mellonella Nuclear Polyhedrosis Viruses.

    M. J. Fraser;Gale E. Smith;Max D. Summers

  • The lepidopteran transposon vector, piggyBac, mediates germ-line transformation in the Mediterranean fruit fly

    Alfred M. Handler;Susan D. McCombs;Malcolm J. Fraser;Stephen H. Saul

  • Silkworms transformed with chimeric silkworm/spider silk genes spin composite silk fibers with improved mechanical properties

    Florence Teulé;Yun-Gen Miao;Bong-Hee Sohn;Young-Soo Kim

  • Assay for Movement of Lepidopteran Transposon IFP2 in Insect Cells Using a Baculovirus Genome as a Target DNA

    Malcolm J. Fraser;Lynne Cary;Kitima Boonvisudhi;Hwei-Gene Heidi Wang

  • Molecular evolutionary analysis of the widespread piggyBac transposon family and related "domesticated" sequences

    A. Sarkar;C. Sim;Y. S. Hong;J. R. Hogan

  • High-efficiency transformation of Plasmodium falciparum by the lepidopteran transposable element piggyBac.

    Bharath Balu;Douglas A. Shoue;Malcolm J. Fraser;John H. Adams

  • Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells

    Donald J. Davidson;Malcolm J. Fraser;Francis J. Castellino

  • Excision of the piggyBac transposable element in vitro is a precise event that is enhanced by the expression of its encoded transposase

    Teresa A. Elick;Christopher A. Bauser;M. J. Fraser

  • Ultrastructural observations of virion maturation in Autographa californica nuclear polyhedrosis virus infected Spodoptera frugiperda cell cultures

    M.J. Fraser

  • Recombinant baculovirus occlusion bodies in vaccines and biological insecticides

    Malcolm J. Fraser;Elliot D. Rosen;Victoria A. Ploplis

  • Expression of eukaryotic genes in insect cultures.

    Fraser Mj

  • Transposon-mediated mutagenesis of a baculovirus

    M.J. Fraser;John S. Brusca;Gale E. Smith;Max D. Summers

  • piggyBac internal sequences are necessary for efficient transformation of target genomes.

    X. Li;R. A. Harrell;A. M. Handler

  • The isolation and characterization of the MP and FP plaque variants of Galleria mellonella nuclear polyhedrosis virus.

    M.J. Fraser;W.F. Hink

  • Characterization and Subcellular Localization of Human Pmel 17/silver, a 100-kDa (Pre)Melanosomal Membrane Protein Associated With 5,6,-Dihydroxyindole-2-Carboxylic Acid (DHICA) Converting Activity

    Zang H. Lee;Ling Hou;Gisela Moellmann;Elizabeth Kuklinska

Frequent Co-Authors

Donald L. Jarvis
Donald L. Jarvis University of Wyoming
Max D. Summers
Max D. Summers Texas A&M University
Byoung S. Kwon
Byoung S. Kwon Tulane University
John H. Adams
John H. Adams University of South Florida
Randolph V. Lewis
Randolph V. Lewis Utah State University
Geoffrey N. Gobert
Geoffrey N. Gobert Queen's University Belfast
Francis J. Castellino
Francis J. Castellino University of Notre Dame
Paul J. Brindley
Paul J. Brindley George Washington University
Anna-Lise Williamson
Anna-Lise Williamson University of Cape Town
Frank H. Collins
Frank H. Collins University of Notre Dame

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