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Katri Pylkäs

Katri Pylkäs

Overview

Katri Pylkäs is affiliated with the University of Oulu in Finland and has an extensive publication record in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research primarily focuses on Genetics and Molecular Biology, with notable attention to Cardiology and Cardiovascular Medicine, Oncology, and Cancer Research.

The scientist's recent papers include:

  • Optical Genome Mapping as an Alternative to FISH-Based Cytogenetic Assessment in Chronic Lymphocytic Leukemia, 2023, published in Cancers
  • Exome sequencing identifies a recurrent variant in SERPINA3 associating with hereditary susceptibility to breast cancer, 2020, published in European Journal of Cancer
  • Incorporating progesterone receptor expression into the PREDICT breast prognostic model, 2022, published in European Journal of Cancer
  • A novel variant in SMG9 causes intellectual disability, confirming a role for nonsense-mediated decay components in neurocognitive development, 2022, published in European Journal of Human Genetics
  • Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent, 2020, published in UNC Libraries

The frequent co-authors collaborating with Katri Pylkäs are:

  • Robert Winqvist
  • Manjeet K. Bolla
  • Thilo Dörk
  • Tuomo Mantere
  • Anna Tervasmäki

The scientist publishes regularly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • European Journal of Cancer
  • UNC Libraries
  • Familial Cancer

Pylkäs's research covers several main topics, including:

  • BRCA gene mutations in cancer
  • Cancer Genomics and Diagnostics
  • DNA Repair Mechanisms
  • Genomics and Rare Diseases
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular Effects of Exercise
  • Genetic factors in colorectal cancer

Best Publications

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • Breast-Cancer Risk in Families with Mutations in PALB2

    A. C. Antoniou;S. Casadei;T. Heikkinen;D. Barrowdale

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

    John R.B. Perry;Felix Day;Cathy E. Elks;Patrick Sulem

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • A recurrent mutation in PALB2 in Finnish cancer families

    Hannele Erkko;Bing Xia;Jenni Nikkilä;Johanna Schleutker

  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Felix R. Day;Katherine S. Ruth;Deborah J Thompson;Kathryn L. Lunetta

  • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

    Antonis C. Antoniou;Xianshu Wang;Zachary S. Fredericksen;Lesley McGuffog

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association analysis identifies three new breast cancer susceptibility loci

    Maya Ghoussaini;Olivia Fletcher;Kyriaki Michailidou;Clare Turnbull

  • Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

    Xin Yang;Goska Leslie;Alicja Doroszuk;Sandra Schneider

  • A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer

    Christopher A. Haiman;Gary K. Chen;Celine M. Vachon;Federico Canzian

  • Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

    Juliet D. French;Maya Ghoussaini;Stacey L. Edwards;Kerstin B. Meyer

  • Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

    Yan Guo;Shaneda Warren Andersen;Xiao-Ou Shu;Kyriaki Michailidou

  • Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Felix R. Day;Katherine S. Ruth;Deborah J. Thompson;Kathryn L. Lunetta

Frequent Co-Authors

Robert Winqvist
Robert Winqvist University of Oulu
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Melissa C. Southey
Melissa C. Southey Monash University
Heli Nevanlinna
Heli Nevanlinna University of Helsinki
Vessela N. Kristensen
Vessela N. Kristensen Oslo University Hospital
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Alison M. Dunning
Alison M. Dunning University of Cambridge
Marjanka K. Schmidt
Marjanka K. Schmidt Antoni van Leeuwenhoek Hospital
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute

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