Junya Toguchida focuses on Molecular biology, Gene, Cancer research, Genetics and Pathology. Junya Toguchida has researched Molecular biology in several fields, including Methylation, Gene expression, DNA methylation, Regulation of gene expression and Mesenchymal stem cell. All of his Gene and Exon, Nonsense mutation, Southern blot and Mutation investigations are sub-components of the entire Gene study.
His research integrates issues of Tumor suppressor gene and Immunohistochemistry in his study of Cancer research. His Pathology study incorporates themes from Lagomorpha, Tibia and Bone resorption. The various areas that Junya Toguchida examines in his Allele study include Retinoblastoma and Chromosome.
His primary areas of investigation include Cancer research, Molecular biology, Pathology, Cell biology and Gene. His Cancer research research incorporates elements of Tumor suppressor gene, Cell culture, Cancer and Immunohistochemistry. His Molecular biology research is multidisciplinary, incorporating perspectives in Gene expression, Small interfering RNA, Gene mutation, Restriction fragment length polymorphism and Regulation of gene expression.
The Pathology study combines topics in areas such as Tumor progression and Gene expression profiling. Junya Toguchida has included themes like Cellular differentiation, In vitro and Induced pluripotent stem cell in his Cell biology study. His Gene study introduces a deeper knowledge of Genetics.
Junya Toguchida mainly focuses on Induced pluripotent stem cell, Cell biology, Cancer research, Fibrodysplasia ossificans progressiva and Pathology. His Induced pluripotent stem cell study is concerned with the field of Gene as a whole. His Cell biology research includes themes of Paraxial mesoderm, Cellular differentiation and Transcriptome.
He is interested in Osteosarcoma, which is a branch of Cancer research. His study with Mutation involves better knowledge in Genetics. His Clinical uses of mesenchymal stem cells research focuses on KOSR and how it relates to Molecular biology.
Junya Toguchida mainly investigates Cell biology, Induced pluripotent stem cell, Cancer research, Chondrogenesis and Fibrodysplasia ossificans progressiva. His studies in Cell biology integrate themes in fields like Embryonic stem cell, Cellular differentiation, Paraxial mesoderm, Transcriptome and Regulation of gene expression. The study incorporates disciplines such as Molecular biology and Stem cell in addition to Embryonic stem cell.
Junya Toguchida focuses mostly in the field of Regulation of gene expression, narrowing it down to matters related to Synovial sarcoma and, in some cases, Genetics and Epigenetics. He specializes in Cancer research, namely Osteosarcoma. As a part of the same scientific study, Junya Toguchida usually deals with the Chondrogenesis, concentrating on Endochondral ossification and frequently concerns with Lineage, Gene and Neural crest.
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Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene.
T Sakai;J Toguchida;N Ohtani;D W Yandell.
American Journal of Human Genetics (1991)
Mutation spectrum of the p53 gene in bone and soft tissue sarcomas.
Junya Toguchida;Toshikazu Yamaguchi;Bruce Ritchie;Roberta L. Beauchamp.
Cancer Research (1992)
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
Masatoshi Kajiwara;Takashi Aoi;Keisuke Okita;Ryosuke Takahashi.
Proceedings of the National Academy of Sciences of the United States of America (2012)
Prevalence and Spectrum of Germline Mutations of the p53 Gene among Patients with Sarcoma
Junya Toguchida;Toshikazu Yamaguchi;Siri H. Dayton;Roberta L. Beaughamp.
The New England Journal of Medicine (1992)
Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells.
Takeshi Okamoto;Tomoki Aoyama;Tomitaka Nakayama;Takeharu Nakamata.
Biochemical and Biophysical Research Communications (2002)
Mutation Spectrum of the Retinoblastoma Gene in Osteosarcomas
Bun-ichiro Wadayama;Junya Toguchida;Takashi Shimizu;Kanji Ishizaki.
Cancer Research (1994)
Frequency and structure of p53 rearrangements in human osteosarcoma
C. W. Miller;A. Aslo;C. Tsay;D. Slamon.
Cancer Research (1990)
Expression of the p16INK4A gene is associated closely with senescence of human mesenchymal stem cells and is potentially silenced by DNA methylation during in vitro expansion.
Kotaro R. Shibata;Tomoki Aoyama;Yasuko Shima;Kenichi Fukiage.
Stem Cells (2007)
Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma.
Junya Toguchida;Kanji Ishizaki;Masao S. Sasaki;Mituo Ikenaga.
Cancer Research (1988)
Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma.
Junya Toguchida;Kanji Ishizaki;Masao S. Sasaki;Yusuke Nakamura.
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