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Biology and Biochemistry

D-Index
56
Citations
13355
World Ranking
14289
National Ranking
302

Overview

Jordi Xaus is affiliated with Oryzon Genomics in Spain, contributing to the fields of biochemistry, genetics, and molecular biology with a research focus that spans medicine and several subfields. Their work involves molecular biology, genetics, neurology, physiology, and hematology.

The scientist's main research topics include histone deacetylase inhibitors, sphingolipid metabolism and signaling, adenosine and purinergic signaling, acute myeloid leukemia research, chronic myeloid leukemia treatments, myeloproliferative neoplasms: diagnosis and treatment, and epigenetics and DNA methylation.

Recent papers authored or co-authored by Jordi Xaus cover a range of topics within these areas:

  • Iadademstat in combination with azacitidine in patients with newly diagnosed acute myeloid leukaemia (ALICE): an open-label, phase 2a dose-finding study, 2024, The Lancet Haematology
  • Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis, 2022, Pharmaceutics
  • Vafidemstat in mild to moderate Alzheimer's disease: The ETHERAL study European cohort interim analysis, 2020, Alzheimer s & Dementia
  • REIMAGINE: A central nervous system basket trial showing safety and efficacy of vafidemstat on aggression in different psychiatric disorders, 2025, Psychiatry and Clinical Neurosciences
  • Efficacy of vafidemstat in experimental autoimmune encephalomyelitis highlights the KDM1A/RCOR1/HDAC epigenetic axis in multiple sclerosis, 2021, Research Square (Research Square)

Frequent co-authors working alongside Jordi Xaus include Carlos Buesa, Tamara Maes, Cristina Mascaró, Natalia Sacilotto, and S. Gutiérrez.

The scientific output has been published in various venues with repeated publications in:

  • Research Square (Research Square)
  • The Lancet Haematology
  • Pharmaceutics
  • Psychiatry and Clinical Neurosciences
  • Alzheimer s & Dementia

Best Publications

  • Is meconium from healthy newborns actually sterile

    Esther Jiménez;María L. Marín;Rocío Martín;Juan M. Odriozola

  • Human milk is a source of lactic acid bacteria for the infant gut.

    Rocío Martín;Susana Langa;Carlota Reviriego;Esther Jimínez

  • Isolation of commensal bacteria from umbilical cord blood of healthy neonates born by cesarean section.

    Esther Jiménez;Leonides Fernández;María L. Marín;Rocío Martín

  • In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway.

    Mònica Comalada;Desirée Camuesco;Saleta Sierra;Isabel Ballester

  • Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship.

    Mònica Comalada;Isabel Ballester;Elvira Bailón;Saleta Sierra

  • LPS induces apoptosis in macrophages mostly through the autocrine production of TNF-α

    Jordi Xaus;Moònica Comalada;Annabel F. Valledor;Jorge Lloberas

  • Probiotic potential of 3 Lactobacilli strains isolated from breast milk.

    Rocío Martín;Mónica Olivares;María L. Marín;Leonides Fernández

  • Oral intake of Lactobacillus fermentum CECT5716 enhances the effects of influenza vaccination.

    Mónica Olivares;Maria Paz Díaz-Ropero;Saleta Sierra;Federico Lara-Villoslada

  • The commensal microflora of human milk: new perspectives for food bacteriotherapy and probiotics

    Rocı́o Martı́n;Susana Langa;Carlota Reviriego;Esther Jiménez

  • Antimicrobial potential of four Lactobacillus strains isolated from breast milk

    M. Olivares;M.P. Díaz-Ropero;R. Martín;J.M. Rodríguez

  • Oral Administration of Lactobacillus Strains Isolated from Breast Milk as an Alternative for the Treatment of Infectious Mastitis during Lactation

    E. Jiménez;L. Fernández;A. Maldonado;R. Martín

  • The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype

    Mònica Comalada;Elvira Bailón;Oscar de Haro;Federico Lara-Villoslada

  • Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis

    Desirée Camuesco;Julio Gálvez;Ana Nieto;Mònica Comalada

  • Lactobacillus salivarius CECT 5713, a potential probiotic strain isolated from infant feces and breast milk of a mother-child pair.

    R. Martín;E. Jiménez;M. Olivares;M.L. Marín

  • Interferon γ Induces the Expression of p21waf-1 and Arrests Macrophage Cell Cycle, Preventing Induction of Apoptosis

    Jordi Xaus;Marina Cardó;Annabel F Valledor;Concepció Soler

  • IFN-gamma up-regulates the A2B adenosine receptor expression in macrophages: a mechanism of macrophage deactivation.

    Jordi Xaus;Maribel Mirabet;Jorge Lloberas;Concepció Soler

  • Dietary eicosapentaenoic acid and docosahexaenoic acid equally incorporate as decosahexaenoic acid but differ in inflammatory effects.

    Saleta Sierra;Federico Lara-Villoslada;Mònica Comalada;Mónica Olivares

  • Two Lactobacillus strains, isolated from breast milk, differently modulate the immune response

    M.P. Díaz-Ropero;R. Martín;S. Sierra;F. Lara-Villoslada

  • Oligosaccharides isolated from goat milk reduce intestinal inflammation in a rat model of dextran sodium sulfate-induced colitis.

    Federico Lara-Villoslada;Elisabeth Debras;Ana Nieto;Angel Concha

  • A comparative study of the preventative effects exerted by two probiotics, Lactobacillus reuteri and Lactobacillus fermentum, in the trinitrobenzenesulfonic acid model of rat colitis

    Laura Peran;Saleta Sierra;Mònica Comalada;Federico Lara-Villoslada

Frequent Co-Authors

Antonio Celada
Antonio Celada University of Barcelona
Juan M. Rodríguez
Juan M. Rodríguez Complutense University of Madrid
Julio Gálvez
Julio Gálvez University of Granada
Antonio Zarzuelo
Antonio Zarzuelo University of Granada
Leonides Fernández
Leonides Fernández Complutense University of Madrid
Rosario Martín
Rosario Martín Complutense University of Madrid
Richard F. Lockey
Richard F. Lockey University of South Florida
F. Estelle R. Simons
F. Estelle R. Simons University of Manitoba
Margitta Worm
Margitta Worm Charité - University Medicine Berlin
Huub F. J. Savelkoul
Huub F. J. Savelkoul Wageningen University & Research

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