John E. Sims

Overview

Best Publications

• The IL-1 family: regulators of immunity

  John E. Sims;Dirk E. Smith

  1807
  Citations

• Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

  Katherine A. Fitzgerald;Eva M. Palsson-McDermott;Andrew G. Bowie;Andrew G. Bowie;Caroline A. Jefferies

  1679
  Citations

• cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily

  J E Sims;C J March;D Cosman;M B Widmer

  1318
  Citations

• Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4

  Francesco Colotta;Fabio Re;Marta Muzio;Riccardo Bertini

  1292
  Citations

• Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis

  Slaheddine Marrakchi;Philippe Guigue;Blair R. Renshaw;Anne Puel

  1091
  Citations

• A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

  C.J. McMahan;J.L. Slack;B. Mosley;D. Cosman

  1073
  Citations

• The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

  Bruce Mosley;M.Patricia Beckmann;Carl J. March;Rejean L. Idzerda

  914
  Citations

• SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.

  David N Wald;Jinzhong Qin;Zhendong Zhao;Youcun Qian

  874
  Citations

• Interleukin 1 signaling occurs exclusively via the type I receptor.

  J E Sims;M A Gayle;J L Slack;M R Alderson

  814
  Citations

• Interleukin (IL)-1F6, IL-1F8, and IL-1F9 Signal through IL-1Rrp2 and IL-1RAcP to Activate the Pathway Leading to NF-κB and MAPKs

  Jennifer E. Towne;Kirsten E. Garka;Blair R. Renshaw;G. Duke Virca

  555
  Citations

• Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.

  Linda S. Park;Unja Martin;Kirsten Garka;Brian Gliniak

  535
  Citations

• The type II 'decoy' receptor: a novel regulatory pathway for interleukin 1.

  Francesco Colotta;Steven K. Dower;John E. Sims;Alberto Mantovani;Alberto Mantovani

  509
  Citations

• Cloning of a Novel Receptor Subunit, AcPL, Required for Interleukin-18 Signaling

  Teresa L. Born;Elisabeth Thomassen;Timothy A. Bird;John E. Sims

  498
  Citations

• Four New Members Expand the Interleukin-1 Superfamily

  Dirk E. Smith;Blair R. Renshaw;Randal R. Ketchem;Marek Kubin

  429
  Citations

• Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways.

  Jennifer L. Slack;K. Schooley;Timothy P. Bonnert;Jennifer L. Mitcham

  421
  Citations

• Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation.

  Hal Blumberg;Huyen Dinh;Esther S. Trueblood;James Pretorius

  417
  Citations

• IL-1 family nomenclature

  Charles Dinarello;William Arend;John Sims;Dirk Smith

  413
  Citations

• Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity.

  Jennifer E. Towne;Blair R. Renshaw;Jason Douangpanya;Brian P. Lipsky

  394
  Citations

• Cloning the interleukin 1 receptor from human T cells

  J E Sims;R B Acres;C E Grubin;C J McMahan

  385
  Citations

• IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP.

  Patricia Parnet;Kirsten E. Garka;Timothy P. Bonnert;Steven K. Dower

  369
  Citations