Jie Zhou

Best Publications

• Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study.

  Hin Chu;Jasper Fuk-Woo Chan;Jasper Fuk-Woo Chan;Terrence Tsz-Tai Yuen;Huiping Shuai

  967
  Citations

• Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

  Jasper Fuk Woo Chan;Yanfeng Yao;Man Lung Yeung;Wei Deng

  749
  Citations

• Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.

  Hin Chu;Jasper Fuk-Woo Chan;Yixin Wang;Terrence Tsz-Tai Yuen

  723
  Citations

• Infection of bat and human intestinal organoids by SARS-CoV-2.

  Jie Zhou;Cun Li;Xiaojuan Liu;Man Chun Chiu

  624
  Citations

• Active Replication of Middle East Respiratory Syndrome Coronavirus and Aberrant Induction of Inflammatory Cytokines and Chemokines in Human Macrophages: Implications for Pathogenesis

  Jie Zhou;Hin Chu;Cun Li;Bosco Ho-Yin Wong

  545
  Citations

• Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

  Hin Chu;Jie Zhou;Bosco Ho-Yin Wong;Cun Li

  473
  Citations

• Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus

  Jie Zhou;Cun Li;Guangyu Zhao;Hin Chu

  419
  Citations

• Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

  David C. Tscharke;David C. Tscharke;Gunasegaran Karupiah;Jie Zhou;Tara Palmore

  378
  Citations

• Differentiated human airway organoids to assess infectivity of emerging influenza virus

  Jie Zhou;Cun Li;Norman Sachs;Man Chun Chiu

  310
  Citations

• SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

  Shuofeng Yuan;Hin Chu;Jasper Fuk Woo Chan;Zi Wei Ye

  249
  Citations

• Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response.

  Hin Chu;Jie Zhou;Bosco Ho-Yin Wong;Cun Li

  213
  Citations

• Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells.

  Hin Chu;Che-Man Chan;Xi Zhang;Yixin Wang

  192
  Citations

• Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza

  Zhongshan Cheng;Jie Zhou;Kelvin Kai Wang To;Hin Chu

  190
  Citations

• MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2.

  Man-Lung Yeung;Yanfeng Yao;Lilong Jia;Jasper F. W. Chan

  184
  Citations

• Emerging SARS-CoV-2 variants expand species tropism to murines.

  Huiping Shuai;Jasper Fuk-Woo Chan;Terrence Tsz-Tai Yuen;Chaemin Yoon

  181
  Citations

• Attenuated Interferon and Proinflammatory Response in SARS-CoV-2-Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation.

  Dong Yang;Dong Yang;Hin Chu;Hin Chu;Yuxin Hou;Yuxin Hou;Yue Chai;Yue Chai

  179
  Citations

• A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses.

  Hanjun Zhao;Jie Zhou;Ke Zhang;Hin Chu

  163
  Citations

• Selective functional deficit in dendritic cell--T cell interaction is a crucial mechanism in chronic hepatitis B virus infection.

  B. J. Zheng;J. Zhou;D. Qu;K. L. Siu

  144
  Citations

• Host and viral determinants for efficient SARS-CoV-2 infection of the human lung.

  Hin Chu;Bingjie Hu;Xiner Huang;Yue Chai

  139
  Citations

• Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters.

  Andrew Chak Yiu Lee;Anna Jinxia Zhang;Jasper Fuk Woo Chan;Jasper Fuk Woo Chan;Can Li

  133
  Citations