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Jan Eggermont

Jan Eggermont

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
7652
World Ranking
15856
National Ranking
270

Overview

Jan Eggermont is affiliated with KU Leuven in Belgium. Their research spans multiple fields mainly within Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on molecular biology, public health, environmental and occupational health, biochemistry, neurology, and physiology.

The scientist's primary topics of research include:

  • Polyamine Metabolism and Applications
  • Innovations in Medical Education
  • Amino Acid Enzymes and Metabolism
  • Clinical Reasoning and Diagnostic Skills
  • Parkinson's Disease Mechanisms and Treatments
  • Lysosomal Storage Disorders Research
  • Cannabis and Cannabinoid Research

Jan Eggermont's publication record includes contributions to well-known venues such as BMC Medical Education, bioRxiv (Cold Spring Harbor Laboratory), Research Square (Research Square), Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, and Biomolecules. The most frequent outlets for their work include:

  • BMC Medical Education
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • Biomolecules

Several recent papers highlight key themes in their research, including:

  • "ATP13A2 deficiency disrupts lysosomal polyamine export," 2020, Nature
  • "ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress," 2020, Proceedings of the National Academy of Sciences
  • "ATP13A3 is a major component of the enigmatic mammalian polyamine transport system," 2020, Journal of Biological Chemistry
  • "Polyamines in Parkinson's Disease: Balancing Between Neurotoxicity and Neuroprotection," 2023, Annual Review of Biochemistry
  • "Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export," 2020, Acta Neuropathologica

Jan Eggermont has collaborated frequently with several researchers, including:

  • Peter Vangheluwe
  • Chris Van den Haute
  • Vasiliki Andreou
  • Birgitte Schoenmakers
  • Veerle Baekelandt

Best Publications

  • Properties of volume-regulated anion channels in mammalian cells

    Bernd Nilius;Jan Eggermont;Thomas Voets;Gunnar Buyse

  • Abnormal intracellular ca(2+)homeostasis and disease.

    L. Missiaen;W. Robberecht;L.Van Den Bosch;G. Callewaert

  • CBS domains: structure, function, and pathology in human proteins

    Sofie Ignoul;Jan Eggermont

  • ATP13A2 deficiency disrupts lysosomal polyamine export

    Sarah van Veen;Shaun Martin;Chris Van den Haute;Veronick Benoy

  • Volume-activated Cl− channels

    Bernd Nilius;Jan Eggermont;Thomas Voets;Guillaume Droogmans

  • Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells

    Meng-Ru Shen;Meng-Ru Shen;Meng-Ru Shen;Guy Droogmans;Jan Eggermont;Thomas Voets

  • Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells.

    Masahiro Kamouchi;Stephan Philipp;Veit Flockerzi;Ulrich Wissenbach

  • Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.

    Bernd Nilius;Thomas Voets;Jean Prenen;Holger Barth

  • Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins.

    Thomas Voets;Vangelis Manolopoulos;Jan Eggermont;Clive Ellory

  • Calcium-activated chloride channels: (un)known, (un)loved?

    Jan Eggermont

  • Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels

    Thomas Voets;Guillaume Droogmans;Gert Raskin;Jan Eggermont

  • Expression of endoplasmic-reticulum Ca2(+)-pump isoforms and of phospholamban in pig smooth-muscle tissues.

    Jan Eggermont;Frank Wuytack;J Verbist;Rik Casteels

  • Cellular function and control of volume-regulated anion channels

    Jan Eggermont;Dominique Trouet;Iris Carton;Bernd Nilius

  • Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.

    Jan Eggermont;N J Proudfoot

  • Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells

    Bernd Nilius;Jean Prenen;Thomas Voets;Jan Eggermont

  • PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes

    Bert Brône;Jan Eggermont

  • Caveolin‐1 modulates the activity of the volume‐regulated chloride channel

    Dominique Trouet;Bernd Nilius;Axel Jacobs;Claude Remacle

  • Volume-activated Cl− currents in different mammalian non-excitable cell types

    Bernd Nilius;J Sehrer;F Viana;C De Greef

  • Antibodies against the non-muscle isoform of the endoplasmic reticulum Ca2(+)-transport ATPase.

    Frank Wuytack;Jan Eggermont;Luc Raeymaekers;L Plessers

  • Interaction between calcium-activated chloride channels and the cystic fibrosis transmembrane conductance regulator.

    L Wei;A Vankeerberghen;Harry Cuppens;Jan Eggermont

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