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Biology and Biochemistry

D-Index
53
Citations
15953
World Ranking
15938
National Ranking
6619

Overview

Jan E. Schnitzer is affiliated with the Beth Israel Deaconess Medical Center in the United States. Their research spans several fields, predominantly within Medicine and Biochemistry, Genetics, and Molecular Biology.

The scientist's work focuses notably on subfields such as Pulmonary and Respiratory Medicine, Cell Biology, Molecular Biology, Modeling and Simulation, and Radiology, Nuclear Medicine and Imaging. Their contributions frequently revolve around topics including Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, Caveolin-1 and cellular processes, Cell Adhesion Molecules Research, COVID-19 epidemiological studies, Monoclonal and Polyclonal Antibodies Research, COVID-19 and healthcare impacts, and Nanoparticle-Based Drug Delivery.

Jan E. Schnitzer has published extensively in various venues. The most frequent publication outlets include:

  • Value in Health
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Medical Research Archives
  • Nature Nanotechnology
  • Physiological Reports

Their recent papers demonstrate a range of interdisciplinary research topics and venues:

  • "Different ODE models of tumor growth can deliver similar results," 2020, BMC Cancer
  • "Characterization of acute lung injury in the bleomycin rat model," 2023, Physiological Reports
  • "Rapid precision targeting of nanoparticles to lung via caveolae pumping system in endothelium," 2024, Nature Nanotechnology
  • "Where Do We Go From Here? A Framework for Using Susceptible-Infectious-Recovered Models for Policy Making in Emerging Infectious Diseases," 2021, Value in Health
  • "Targeting caveolae to pump bispecific antibody to TGF-β into diseased lungs enables ultra-low dose therapeutic efficacy," 2022, PLoS ONE

Jan E. Schnitzer's frequent collaborators reflect interdisciplinary and sustained research partnerships. These coauthors include:

  • Tim Buss
  • Anil H. Kadam
  • James A. Koziol
  • Brittany Cederstrom
  • Bogdan Olenyuk

Best Publications

  • Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules.

    J E Schnitzer;P Oh;E Pinney;J Allard

  • TARGETING OF NITRIC OXIDE SYNTHASE TO ENDOTHELIAL CELL CAVEOLAE VIA PALMITOYLATION : IMPLICATIONS FOR NITRIC OXIDE SIGNALING

    Guillermo Garcia-Cardena;Phil Oh;Jianwei Liu;Jan E. Schnitzer

  • Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium

    Phil Oh;Deirdre P. McIntosh;Jan E. Schnitzer

  • FLOTILLIN AND EPIDERMAL SURFACE ANTIGEN DEFINE A NEW FAMILY OF CAVEOLAE-ASSOCIATED INTEGRAL MEMBRANE PROTEINS

    Perry E. Bickel;Perry E. Bickel;Philipp E. Scherer;Jan E. Schnitzer;Phil Oh

  • Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy

    Phil Oh;Yan Li;Jingyi Yu;Eberhard Durr

  • Separation of caveolae from associated microdomains of GPI-anchored proteins

    Jan E. Schnitzer;Deirdre P. McIntosh;Ann M. Dvorak;Jun Liu

  • Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells

    Sam W Lee;Corinne L Reimer;Phil Oh;Doreen B Campbell

  • Segregation of Heterotrimeric G Proteins in Cell Surface Microdomains: Gq Binds Caveolin to Concentrate in Caveolae, whereas Gi and Gs Target Lipid Rafts by Default

    Phil Oh;Jan E. Schnitzer

  • ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions.

    Mahnaz Razandi;Philip Oh;A. L. I. Pedram;Jan Schnitzer

  • Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture.

    Eberhard Durr;Jingyi Yu;Karolina M Krasinska;Lucy A Carver

  • Endothelial Caveolae Have the Molecular Transport Machinery for Vesicle Budding, Docking, and Fusion Including VAMP, NSF, SNAP, Annexins, and GTPases

    Jan E. Schnitzer;Jun Liu;Phil Oh

  • Label-free, normalized quantification of complex mass spectrometry data for proteomic analysis

    Noelle M Griffin;Jingyi Yu;Fred Long;Phil Oh

  • Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins.

    J.E. Schnitzer;P. Oh

  • Role of GTP Hydrolysis in Fission of Caveolae Directly from Plasma Membranes

    Jan E. Schnitzer;Phil Oh;Deirdre P. McIntosh

  • In Situ Flow Activates Endothelial Nitric Oxide Synthase in Luminal Caveolae of Endothelium with Rapid Caveolin Dissociation and Calmodulin Association

    Victor Rizzo;Deirdre P. McIntosh;Phil Oh;Jan E. Schnitzer

  • Organized Endothelial Cell Surface Signal Transduction in Caveolae Distinct from Glycosylphosphatidylinositol-anchored Protein Microdomains

    Jun Liu;Phil Oh;Thierry Horner;Rick A. Rogers

  • Caveolae: mining little caves for new cancer targets

    Lucy A. Carver;Jan E. Schnitzer

  • Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung.

    Phil Oh;Per Borgström;Halina Witkiewicz;Yan Li

  • Targeting endothelium and its dynamic caveolae for tissue-specific transcytosis in vivo: A pathway to overcome cell barriers to drug and gene delivery

    Deirdre P. McIntosh;Xiang-Yang Tan;Phil Oh;Jan E. Schnitzer

  • Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor.

    Jan E. Schnitzer;Phil Oh;B. S. Jacobson;Ann M. Dvorak

Frequent Co-Authors

James A. Koziol
James A. Koziol Scripps Research Institute
Asrar B. Malik
Asrar B. Malik University of Illinois at Chicago
Robert E. Coleman
Robert E. Coleman University of Sheffield
Simon S. Cross
Simon S. Cross University of Sheffield
Patricia W. Finn
Patricia W. Finn University of Illinois at Chicago
Ellis R. Levin
Ellis R. Levin University of California, Irvine
Peter F. Davies
Peter F. Davies University of Pennsylvania
Robert J. Schneider
Robert J. Schneider New York University
Ann M. Dvorak
Ann M. Dvorak Beth Israel Deaconess Medical Center
Miqin Zhang
Miqin Zhang University of Washington

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