James E. Ferrell

Overview

Best Publications

• STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

  Jen Liou;Man Lyang Kim;Won Do Heo;Joshua T. Jones

  2504
  Citations

• STIM Is a Ca 2+ Sensor Essential for Ca 2+ -Store-Depletion-Triggered Ca 2+ Influx

  Jen Liou;Won Do Heo;Joshua T. Jones;Jason W. Myers

  2314
  Citations

• Mechanisms of specificity in protein phosphorylation

  Jeffrey A. Ubersax;James E. Ferrell

  1718
  Citations

• Ultrasensitivity in the mitogen-activated protein kinase cascade

  Chi Ying F. Huang;James E. Ferrell

  1533
  Citations

• Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability.

  James E Ferrell

  1363
  Citations

• The Biochemical Basis of an All-or-None Cell Fate Switch in Xenopus Oocytes

  James E. Ferrell;Eric M. Machleder

  1302
  Citations

• Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems

  David Angeli;James E. Ferrell;Eduardo D. Sontag

  1264
  Citations

• A positive-feedback-based bistable ‘memory module’ that governs a cell fate decision

  Wen Xiong;James E. Ferrell

  900
  Citations

• Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2

  Joseph R. Pomerening;Eduardo D. Sontag;James E. Ferrell

  881
  Citations

• Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops

  Tony Yu-Chen Tsai;Yoon Sup Choi;Yoon Sup Choi;Wenzhe Ma;Wenzhe Ma;Joseph R. Pomerening

  792
  Citations

• Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs

  James E. Ferrell

  750
  Citations

• Interlinked Fast and Slow Positive Feedback Loops Drive Reliable Cell Decisions

  Onn Brandman;James E. Ferrell;Rong Li;Tobias Meyer

  540
  Citations

• Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA.

  David G. Hendrickson;Daniel J. Hogan;Heather L. McCullough;Jason W. Myers

  524
  Citations

• Untangling the wires: A strategy to trace functional interactions in signaling and gene networks

  Boris N. Kholodenko;Anatoly Kiyatkin;Frank J. Bruggeman;Eduardo Sontag

  503
  Citations

• Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible.

  James E. Ferrell;Wen Xiong

  464
  Citations

• Mechanistic Studies of the Dual Phosphorylation of Mitogen-activated Protein Kinase

  James E. Ferrell;Ramesh R. Bhatt

  462
  Citations

• Systems-Level Dissection of the Cell-Cycle Oscillator: Bypassing Positive Feedback Produces Damped Oscillations

  Joseph R. Pomerening;Sun Young Kim;James E. Ferrell

  413
  Citations

• Selective Regulation of Neurite Extension and Synapse Formation by the β but not the α Isoform of CaMKII

  Charles C Fink;Karl-Ulrich Bayer;Jason W Myers;James E Ferrell

  404
  Citations

• Modeling the cell cycle: why do certain circuits oscillate?

  James E. Ferrell;Tony Yu Chen Tsai;Qiong Yang

  390
  Citations

• Erratum: Mechanisms of specificity in protein phosphorylation

  Jeffrey A. Ubersax;James E. Ferrell

  9
  Citations