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Genetics

D-Index
58
Citations
40414
World Ranking
3280
National Ranking
400

Overview

Hugh Gurling was affiliated with University College London in the United Kingdom throughout their research career. Their work spanned multiple interconnected fields, including genetics, economics and econometrics, and experimental and cognitive psychology. The scientist contributed to understanding complex genetic factors and mental health through a range of publications primarily focused on genomics and rare diseases, as well as health systems and economic evaluations.

The research topics Hugh Gurling engaged with frequently included:

  • Health Systems, Economic Evaluations, Quality of Life
  • Genomics and Rare Diseases
  • BRCA Gene Mutations in Cancer
  • Mental Health Research Topics

Over time, their publications appeared predominantly in several venues, with UNC Libraries hosting four of their papers and Nature Communications housing one. This distribution reflects a blend of institutional repositories and high-impact scientific journals.

Some of the recent papers that featured Hugh Gurling's contributions included:

  • Distinct genetic liability profiles define clinically relevant patient strata across common diseases, 2024, Nature Communications
  • A Comprehensive Family-Based Replication Study of Schizophrenia Genes, 2020, UNC Libraries
  • Rare chromosomal deletions and duplications increase risk of schizophrenia, 2020, UNC Libraries
  • Genome-Wide Association Study of Suicide Attempts in Mood Disorder Patients, 2020, UNC Libraries
  • Mosaic copy number variation in schizophrenia, 2020, UNC Libraries

Throughout their career, Hugh Gurling collaborated frequently with several researchers, indicating a network of professional partnerships in psychiatric genetics and related fields. The most frequent co-authors included:

  • Douglas M. Ruderfer
  • Andrew McQuillin
  • Douglas Blackwood
  • Michael O'Donovan
  • George Kirov

These collaborations and diverse thematic interests contributed to investigations in complex disorders such as schizophrenia and mood disorders, particularly examining genetic influences that intersect with broader health and social outcomes.

Hugh Gurling's work addressed the identification of genetic liability profiles across prevalent diseases and the replication of findings on schizophrenia genes through comprehensive family-based studies. Their research also explored structural genetic variations like rare chromosomal deletions and mosaic copy number variations relevant to psychiatric disorders.

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

    D Harold;R Abraham;P Hollingworth;R Sims

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia

    Cathryn M. Lewis;Douglas F. Levinson;Lesley H. Wise;Lynn E. DeLisi

  • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

    Manuel A R Ferreira;Michael C O'Donovan;Yan A Meng;Ian R Jones

  • Rare chromosomal deletions and duplications increase risk of schizophrenia

    Jennifer L. Stone;Jennifer L. Stone;Jennifer L. Stone;Michael C. O’Donovan;Hugh Gurling;George K. Kirov

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

    Lesley Jones;Peter A. Holmans;Marian L. Hamshere;Denise Harold

  • Localization of a susceptibility locus for schizophrenia on chromosome 5

    Robin Sherrington;Jon Brynjolfsson;Hannes Petursson;Mark Potter

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Genomewide association studies: history, rationale, and prospects for psychiatric disorders.

    Sven Cichon;Nick Craddock;Mark Daly;Mark Daly;Stephen V. Faraone

  • Genomewide Genetic Linkage Analysis Confirms the Presence of Susceptibility Loci for Schizophrenia, on Chromosomes 1q32.2, 5q33.2, and 8p21-22 and Provides Support for Linkage to Schizophrenia, on Chromosomes 11q23.3-24 and 20q12.1-11.23

    Hugh M.D. Gurling;Gursharan Kalsi;Jon Brynjolfson;Thordur Sigmundsson

  • Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.

    Ricardo Segurado;Sevilla D. Detera-Wadleigh;Douglas F. Levinson;Cathryn M. Lewis

  • An integrated genetic-epigenetic analysis of schizophrenia : evidence for co-localization of genetic associations and differential DNA methylation

    Eilis Hannon;Emma Dempster;Joana Viana;Joe Burrage

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimertextquotesingles disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

Frequent Co-Authors

Andrew McQuillin
Andrew McQuillin University College London
David Curtis
David Curtis Queen Mary University of London
Shaun Purcell
Shaun Purcell Harvard Medical School
Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Douglas M. Ruderfer
Douglas M. Ruderfer Vanderbilt University Medical Center
Stephan Ripke
Stephan Ripke Massachusetts General Hospital
Thomas G. Schulze
Thomas G. Schulze Ludwig-Maximilians-Universität München
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill
Michael John Owen
Michael John Owen Cardiff University
Sven Cichon
Sven Cichon University of Basel

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