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Göran Sedvall

Göran Sedvall

D-Index & Metrics

Medicine

D-Index
90
Citations
29988
World Ranking
12201
National Ranking
230

Research.com Recognitions

  • 1998 - Member of the National Academy of Medicine (NAM)

Overview

Göran Sedvall is affiliated with the Karolinska Institute in Sweden. Their research primarily focuses on the molecular mechanisms underlying receptor signaling and the influence of neurotransmitter receptors on behavior. Sedvall's work spans the fields of Biochemistry, Genetics and Molecular Biology, with specific contributions to Molecular Biology and Cellular and Molecular Neuroscience.

Their published research includes detailed studies on dopamine receptors, particularly within the context of pharmacological receptor mechanisms and effects. Two recent papers authored by Jean-Martin Beaulieu with Sedvall's involvement are notable:

  • Dopamine receptors in GtoPdb v.2023.1 (2023), published in IUPHAR/BPS Guide to Pharmacology CITE
  • Dopamine receptors in GtoPdb v.2025.3 (2025), published in IUPHAR/BPS Guide to Pharmacology CITE

Sedvall frequently collaborates with several researchers in the field. These co-authors include:

  • Jean-Martin Beaulieu
  • Emiliana Borrelli
  • Arvid Carlsson
  • Marc G. Caron
  • Olivier Civelli

The primary venue for Sedvall's publications is the IUPHAR/BPS Guide to Pharmacology CITE, reflecting their consistent contributions to standards and updates within this pharmacological resource.

Göran Sedvall has been recognized as a member of the National Academy of Medicine since 1998, marking a significant professional acknowledgment within the medical research community.

Best Publications

  • Positron Emission Tomographic Analysis of Central D1 and D2 Dopamine Receptor Occupancy in Patients Treated With Classical Neuroleptics and Clozapine: Relation to Extrapyramidal Side Effects

    Lars Farde;Anna-Lena Nordström;Frits-Axel Wiesel;Stefan Pauli

  • Quantitative Analysis of D2 Dopamine Receptor Binding in the Living Human Brain by PET

    Lars Farde;Håkan Hall;Erling Ehrin;Göran Sedvall

  • Central D2-Dopamine Receptor Occupancy in Schizophrenic Patients Treated With Antipsychotic Drugs

    Lars Farde;Fritz-Axel Wiesel;Christer Halldin;Göran Sedvall

  • Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers.

    E G Jönsson;M M Nöthen;F Grünhage;L Farde

  • Transplantation of adrenal medullary tissue to striatum in parkinsonism. First clinical trials.

    Erik-Olof Backlund;Per-Ola Granberg;Bertil Hamberger;Evert Knutsson

  • D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride.

    Lars Farde;Frits-Axel Wiesel;Sharon Stone-Elander;Christer Halldin

  • THE DISTRIBUTION OF ADRENERGIC NERVE FIBRES TO THE BLOOD VESSELS IN SKELETAL MUSCLE.

    Kjell Fuxe;Göran Sedvall

  • Distribution of D1- and D2-dopamine receptors, and dopamine and its metabolites in the human brain.

    Håkan Hall;Göran Sedvall;Olle Magnusson;Jutta Kopp

  • In-vivo demonstration of reduced benzodiazepine receptor binding in human epileptic foci.

    Ivanka Savic;Per Roland;Göran Sedvall;Anders Persson

  • D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients.

    A L Nordström;L Farde;S Nyberg;P Karlsson

  • D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics.

    L Farde;F A Wiesel;A L Nordström;G Sedvall

  • Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography.

    Lars Farde;Erling Ehrin;Lars Eriksson;Torgny Greitz

  • No D2 receptor increase in PET study of schizophrenia.

    Lars Farde;Frits-Axel Wiesel;HÅkan Hall;Christer Halldin

  • PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride.

    L Farde;C Halldin;S Stone-Elander;G Sedvall

  • Transplantation in Parkinson's disease: two cases of adrenal medullary grafts to the putamen.

    Olle Lindvall;Erik‐Olof Backlund;Lars Farde;Göran Sedvall

  • Amino acid substitution in the dopamine D3 receptor as a useful polymorphism for investigating psychiatric disorders

    L. Lannfelt;P. Sokoloff;M.-P. Martres;C. Pilon

  • Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]WAY-100635

    H Hall;C Lundkvist;C Halldin;L Farde

  • PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease.

    N Ginovart;A Lundin;L Farde;C Halldin

  • Simultaneous determination of the three major monoamine metabolites in brain tissue and body fluids by a mass fragmentographic method.

    Swahn C-G;B Sandgárde;Wiesel F-A;G Sedvall

  • Sex Differences in Psychoneuroendocrine Reactions to Examination Stress

    Marianne Frankenhaeuser;Aila Collins

Frequent Co-Authors

Lars Farde
Lars Farde Karolinska Institute
Erik G. Jönsson
Erik G. Jönsson University of Oslo
Christer Halldin
Christer Halldin Karolinska Institute
Håkan Hall
Håkan Hall Karolinska Institute
Ingrid Agartz
Ingrid Agartz University of Oslo
Lars Terenius
Lars Terenius Karolinska Institute
Stefan Brené
Stefan Brené Karolinska Institute
Markus M. Nöthen
Markus M. Nöthen University Hospital Bonn
Yasmin L. Hurd
Yasmin L. Hurd Icahn School of Medicine at Mount Sinai
Nils Lindefors
Nils Lindefors Karolinska Institute

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