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Biology and Biochemistry

D-Index
55
Citations
9113
World Ranking
15229
National Ranking
1079

Overview

Frank Thévenod is affiliated with Witten/Herdecke University in Germany. Their research primarily focuses on the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Environmental Science. Within these fields, they have contributed to various subfields including Health, Toxicology and Mutagenesis, Molecular Biology, Nutrition and Dietetics, Hematology, and Pediatrics, Perinatology and Child Health.

Thevenod's work covers a range of topics related to trace elements in health, heavy metal exposure and toxicity, iron metabolism and disorders, drug transport and resistance mechanisms, cancer, hypoxia, and metabolism, erythropoietin and anemia treatment, as well as the impact of toxic organic pollutants.

Among their recent papers are the following publications:

  • Cadmium transport by mammalian ATP-binding cassette transporters, 2024, BioMetals
  • Role of the SLC22A17/lipocalin-2 receptor in renal endocytosis of proteins/metalloproteins: a focus on iron- and cadmium-binding proteins, 2023, American Journal of Physiology-Renal Physiology
  • Increased Endocytosis of Cadmium-Metallothionein through the 24p3 Receptor in an In Vivo Model with Reduced Proximal Tubular Activity, 2021, International Journal of Molecular Sciences
  • Cell organelles as targets of mammalian cadmium toxicity, 2020, Archives of Toxicology
  • Iron and Cadmium Entry Into Renal Mitochondria: Physiological and Toxicological Implications, 2020, Frontiers in Cell and Developmental Biology

Thevenod frequently publishes in these journals:

  • Archives of Toxicology
  • BioMetals
  • Frontiers in Cell and Developmental Biology
  • International Journal of Molecular Sciences
  • American Journal of Physiology-Renal Physiology

Collaborations are an important aspect of Thevenod's research. Frequent co-authors include Wing-Kee Lee, Natascha A. Wolff, Timm Schreiber, Stephanie Probst, and Bettina Scharner.

Best Publications

  • Up-regulation of Multidrug Resistance P-glycoprotein via Nuclear Factor-κB Activation Protects Kidney Proximal Tubule Cells from Cadmium- and Reactive Oxygen Species-induced Apoptosis

    Frank Thévenod;Jenny M. Friedmann;Alice D. Katsen;Ingeborg A. Hauser

  • Cadmium and cellular signaling cascades: to be or not to be?

    Frank Thévenod

  • Nephrotoxicity and the proximal tubule. Insights from cadmium.

    Frank Thévenod

  • Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K+-ATPase through proteasomal and endo-/lysosomal proteolytic pathways

    Frank Thévenod;Jenny M. Friedmann

  • Cadmium and cellular signaling cascades: interactions between cell death and survival pathways.

    Frank Thévenod;Wing-Kee Lee

  • Toxicology of cadmium and its damage to mammalian organs.

    Frank Thévenod;Wing-Kee Lee

  • Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

    Sebastian Barg;Ping Huang;Lena Eliasson;Deborah J. Nelson

  • Catch me if you can! Novel aspects of cadmium transport in mammalian cells

    Frank Thévenod

  • Characterization of inositol 1,4,5-trisphosphate-sensitive (IsCaP) and -insensitive (IisCaP) nonmitochondrial Ca2+ pools in rat pancreatic acinar cells

    Frank Thévenod;Martine Dehlinger-Kremer;Thomas P. Kemmer;Anna-Luise Christian

  • New perspectives in cadmium toxicity: an introduction

    Jean-Marc Moulis;Jean-Marc Moulis;Frank Thévenod

  • Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins.

    Frank Thévenod

  • Anoctamins

    Karl Kunzelmann;Yuemin Tian;Joana Raquel Martins;Diana Faria

  • Highly efficient neural differentiation of human somatic stem cells, isolated by minimally invasive periodontal surgery.

    Darius Widera;Wolf-Dieter Grimm;Jeannette M. Moebius;Ilja Mikenberg

  • Megalin-dependent internalization of cadmium-metallothionein and cytotoxicity in cultured renal proximal tubule cells.

    Natascha A. Wolff;Marouan Abouhamed;Pierre J. Verroust;Frank Thévenod

  • A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese.

    Natascha A Wolff;Michael D Garrick;Lin Zhao;Laura M Garrick

  • Lipocalin-2 (24p3/Neutrophil Gelatinase-associated Lipocalin (NGAL)) Receptor Is Expressed in Distal Nephron and Mediates Protein Endocytosis

    Christian Langelueddecke;Eleni Roussa;Robert A. Fenton;Natascha A. Wolff

  • A role for mitochondrial aquaporins in cellular life-and-death decisions?

    Wing-Kee Lee;Frank Thévenod

  • Glutathione and mitochondria determine acute defense responses and adaptive processes in cadmium-induced oxidative stress and toxicity of the kidney

    Ambily Ravindran Nair;Wing-Kee Lee;Karen Smeets;Quirine Swennen

  • Cd2+-induced cytochrome c release in apoptotic proximal tubule cells: role of mitochondrial permeability transition pore and Ca2+ uniporter

    Wing-Kee Lee;Ulrich Bork;Fatemeh Gholamrezaei;Frank Thévenod

  • Divalent metal transporter 1 in the kidney proximal tubule is expressed in late endosomes/lysosomal membranes: implications for renal handling of protein-metal complexes

    Marouan Abouhamed;Jakub Gburek;Wei Liu;Blazej Torchalski

Frequent Co-Authors

Seth L. Alper
Seth L. Alper Beth Israel Deaconess Medical Center
Ulrich Hopfer
Ulrich Hopfer Case Western Reserve University
Hermann Koepsell
Hermann Koepsell University of Würzburg
Erik Renström
Erik Renström Lund University
Patrik Rorsman
Patrik Rorsman University of Oxford
Winfried Haase
Winfried Haase Max Planck Society
Lena Eliasson
Lena Eliasson Lund University
Hugo R. de Jonge
Hugo R. de Jonge Erasmus University Rotterdam
Achim D. Gruber
Achim D. Gruber Freie Universität Berlin

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