World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
36570
World Ranking
6840
National Ranking
3156

Research.com Recognitions

  • 2001 - Fellow of Alfred P. Sloan Foundation

Overview

Fen-Biao Gao is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Neurology, Molecular Biology, Genetics, Cell Biology, and Cellular and Molecular Neuroscience as key subfields.

The main research topics covered by their work include Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, Prion Diseases and Protein Misfolding, RNA Research and Splicing, Neuroinflammation and Neurodegeneration Mechanisms, Alzheimer's disease research and treatments, and Autophagy in Disease and Therapy.

Fen-Biao Gao has published extensively in multiple venues. The frequent publication venues include Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Neuron, Cell, and Cell Reports.

Recent notable papers by Fen-Biao Gao include:

  • "p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)" (2021, Cell)
  • "PIKFYVE inhibition mitigates disease in models of diverse forms of ALS" (2023, Cell)
  • "Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons" (2022, Neuron)
  • "Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM" (2022, Nature Communications)
  • "CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro" (2022, Nature Communications)

Coauthors frequently collaborating with Fen-Biao Gao include:

  • Gopinath Krishnan
  • Sandra Almeida
  • Justin K. Ichida
  • Soojin Lee
  • Leonard Petrucelli

Fen-Biao Gao received the Fellowship of the Alfred P. Sloan Foundation in 2001.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

    Brian D. Freibaum;Yubing Lu;Rodrigo Lopez-Gonzalez;Nam Chul Kim

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules.

    Sebastian Markmiller;Sahar Soltanieh;Kari L. Server;Raymond Mak

  • ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration.

    Jin-A Lee;Anne Beigneux;S. Tariq Ahmad;Stephen G. Young

  • Genes regulating dendritic outgrowth, branching, and routing in Drosophila

    Fen Biao Gao;Jay E. Brenman;Lily Yeh Jan;Yuh Nung Jan

  • Accumulation of the cyclin‐dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation

    Béatrice Durand;Fen‐Biao Gao;Martin Raff

  • Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.

    Rodrigo Lopez-Gonzalez;Yubing Lu;Tania F. Gendron;Anna Karydas

  • MicroRNA-9 Coordinates Proliferation and Migration of Human Embryonic Stem Cell-Derived Neural Progenitors

    Celine Delaloy;Lei Liu;Jin-A Lee;Hua Su

  • Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons

    Sandra Almeida;Eduardo Gascon;Hélène Tran;Hsin Jung Chou

  • MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila

    Yan Li;Fay Wang;Jin-A Lee;Fen-Biao Gao

  • Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1.

    Alan Lee;Wenjun Li;Kanyan Xu;Brigitte A. Bogert

  • Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity

    Tse-Chun Kuo;Chun-Ting Chen;Desiree Baron;Tamer T. Onder

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Control of dendritic field formation in Drosophila: the roles of flamingo and competition between homologous neurons.

    Fen Biao Gao;Minoree Kohwi;Jay E. Brenman;Lily Yeh Jan

  • Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice

    Owen Morgan Peters;Gabriela Toro Cabrera;Helene Tran;Tania F. Gendron

  • Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1

    Fen Biao Gao;Craig C. Carson;Todd Levine;Jack D. Keene

  • Context-dependent functions of specific microRNAs in neuronal development

    Fen-Biao Gao

Frequent Co-Authors

Bruce L. Miller
Bruce L. Miller University of California, San Francisco
Tania F. Gendron
Tania F. Gendron Mayo Clinic
Robert V. Farese
Robert V. Farese Harvard University
J. Paul Taylor
J. Paul Taylor St. Jude Children's Research Hospital
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Martin Raff
Martin Raff University College London
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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