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Biology and Biochemistry

D-Index
58
Citations
17666
World Ranking
12954
National Ranking
268

Overview

Fatima Al-Shahrour is affiliated with the Spanish National Cancer Research Centre in Spain. Their research predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. The scientist's work covers various subfields, including Molecular Biology, Cancer Research, Oncology, Immunology, and Genetics.

The primary topics investigated by Fatima Al-Shahrour include Cancer Genomics and Diagnostics, Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, Single-cell and Spatial Transcriptomics, Genetic Factors in Colorectal Cancer, Cancer, Hypoxia, and Metabolism, and Immune Cell Function and Interaction.

Notable recent publications by Fatima Al-Shahrour include:

  • The repertoire of mutational signatures in human cancer, 2020, Nature
  • Pan-cancer analysis of whole genomes, 2020, Nature
  • Patterns of somatic structural variation in human cancer genomes, 2020, Nature
  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing, 2020, Nature Genetics
  • Comprehensive molecular characterization of mitochondrial genomes in human cancers, 2020, Nature Genetics

Fatima Al-Shahrour has frequently published in several scientific venues, including Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Nature Genetics, Nature, and Zenodo (CERN European Organization for Nuclear Research).

Their collaborative network features frequent co-authors such as Kadir C. Akdemir, David J. Adams, Malik Alawi, Ludmil B. Alexandrov, and Eva G. Álvarez.

Best Publications

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes

    Fátima Al-Shahrour;Ramón Díaz-Uriarte;Joaquín Dopazo

  • Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

    Marc H. G. P. Raaijmakers;Siddhartha Mukherjee;Shangqin Guo;Siyi Zhang

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

    Biola M. Javierre;Agustin F. Fernandez;Julia Richter;Fatima Al-Shahrour

  • Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis

    Raajit Rampal;Raajit Rampal;Fatima Al-Shahrour;Omar Abdel-Wahab;Omar Abdel-Wahab;Jay P. Patel

  • Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

    Michael G Kharas;Michael G Kharas;Christopher J Lengner;Fatima Al-Shahrour;Fatima Al-Shahrour;Lars Bullinger

  • Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor

    Camilla L. Christensen;Nicholas Kwiatkowski;Brian J. Abraham;Julian Carretero

  • Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells

    Ann Mullally;Steven W. Lane;Steven W. Lane;Brian Ball;Christine Megerdichian

  • BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments

    Fátima Al-Shahrour;Pablo Minguez;Joaquín Tárraga;David Montaner

  • FatiGO +: a functional profiling tool for genomic data. Integration of functional annotation, regulatory motifs and interaction data with microarray experiments

    Fátima Al-Shahrour;Pablo Minguez;Joaquín Tárraga;Ignacio Medina

  • BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments

    Fátima Al-Shahrour;Pablo Minguez;Juan M. Vaquerizas;Lucía Conde

  • Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation

    Shannon Elf;Nouran S. Abdelfattah;Edwin Chen;Javier Perales-Patón

  • GEPAS: a web-based resource for microarray gene expression data analysis

    Javier Herrero;Fátima Al-Shahrour;Ramón Díaz-Uriarte;Álvaro Mateos

  • Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

    Rishi V. Puram;Rishi V. Puram;Monika S. Kowalczyk;Carl G. de Boer;Rebekka K. Schneider

  • In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling

    Peter G. Miller;Fatima Al-Shahrour;Fatima Al-Shahrour;Kimberly A. Hartwell;Lisa P. Chu

  • Integrated Next Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment

    Elena Garralda;Keren Paz;Pedro P. López-Casas;Siân Jones

  • Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

    Sun-Mi Park;Raquel P. Deering;Yuheng Lu;Patrick Tivnan

  • Discovering molecular functions significantly related to phenotypes by combining gene expression data and biological information

    Fátima Al-Shahrour;Ramón Díaz-Uriarte;Joaquín Dopazo

  • Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

    Rishi V. Puram;Monika S. Kowalczyk;Carl G. de Boer;Rebekka K. Schneider

Frequent Co-Authors

Lars Bullinger
Lars Bullinger Charité - University Medicine Berlin
Benjamin L. Ebert
Benjamin L. Ebert Harvard University
Joaquín Dopazo
Joaquín Dopazo Institute of Biomedicine of Seville
Alfonso Valencia
Alfonso Valencia Barcelona Supercomputing Center
Gonzalo Gómez-López
Gonzalo Gómez-López Universidade de Vigo
D. Gary Gilliland
D. Gary Gilliland Fred Hutchinson Cancer Research Center
Christopher J. Lengner
Christopher J. Lengner University of Pennsylvania
Kwok-Kin Wong
Kwok-Kin Wong New York University
Juan M. Vaquerizas
Juan M. Vaquerizas Max Planck Society
George Q. Daley
George Q. Daley Boston Children's Hospital

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