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Genetics

D-Index
65
Citations
43192
World Ranking
2648
National Ranking
1167

Overview

Elizabeth K. Speliotes is affiliated with the University of Michigan-Ann Arbor in the United States. Their academic work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology with a significant focus on subfields including Epidemiology, Genetics, Molecular Biology, Endocrinology, Diabetes and Metabolism, and Surgery.

Their research topics encompass an array of subjects such as liver disease diagnosis and treatment, diet and metabolism studies, genetic associations and epidemiology, endoplasmic reticulum stress and disease, inflammatory bowel disease, and lipid metabolism and disorders.

Frequent publication venues for their work include Gastroenterology, where they have contributed 15 publications, UNC Libraries with 8 publications, bioRxiv (Cold Spring Harbor Laboratory) with 7 publications, Journal of Hepatology with 6, and Nature Genetics with 2.

Elizabeth K. Speliotes has collaborated extensively with several co-authors, most notably with Xiaomeng Du (28 collaborations), Vincent Chen (27), Yanhua Chen (21), Annapurna Kuppa (21), and Antonino Oliveri (16).

Selected notable publications include:

  • Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease, 2023, Nature Genetics
  • rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis, 2020, Journal of Hepatology
  • Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology, 2021, Nature Communications
  • PNPLA3 Genotype and Diabetes Identify Patients With Nonalcoholic Fatty Liver Disease at High Risk of Incident Cirrhosis, 2023, Gastroenterology
  • Comprehensive genetic study of the insulin resistance marker TG:HDL-C in the UK Biobank, 2024, Nature Genetics

Best Publications

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels

    Richa Saxena;Benjamin F. Voight;Valeriya Lyssenko;Noël P. Burtt

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    E. K. Speliotes;C. J. Willer;S. I. Berndt;K. L. Monda

  • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Iris M. Heid;Anne U. Jackson;Joshua C. Randall;Tthomas W. Winkler

  • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

    Elizabeth K. Speliotes;Laura M. Yerges-Armstrong;Jun Wu;Ruben Hernaez;Ruben Hernaez

  • Loss-of-function mutations in APOC3, triglycerides, and coronary disease

    Jacy Crosby;Gina M. Peloso;Gina M. Peloso;Paul L. Auer;David R. Crosslin

  • Biological interpretation of genome-wide association studies using predicted gene functions

    Tune H Pers;Juha M Karjalainen;Yingleong Chan;Harm-Jan Westra

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I Berndt;Stefan Gustafsson;Stefan Gustafsson;Reedik Mägi;Reedik Mägi;Andrea Ganna

  • Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

    Cecilia M. Lindgren;Iris M. Heid;Joshua C. Randall;Claudia Lamina

  • Exome-wide association study of plasma lipids in > 300,000 individuals

    Dajiang J Liu;Gina M Peloso;Gina M Peloso;Haojie Yu;Adam S Butterworth;Adam S Butterworth

  • The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits

    B F Voight;H M Kang;J Ding;C D Palmer;C D Palmer

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • FTO genotype is associated with phenotypic variability of body mass index

    Jian Yang;Jian Yang;Ruth J F Loos;Ruth J F Loos;Joseph E. Powell;Joseph E. Powell;Sarah E. Medland

  • PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Johannah L. Butler;Johannah L. Butler;Cameron D. Palmer;Cameron D. Palmer;Benjamin F. Voight;Benjamin F. Voight

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I. Berndt;Stefan Gustafsson;Reedik Maegi;Andrea Ganna

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    H. Lango Allen;K. Estrada;G. Lettre;S. I. Berndt

Frequent Co-Authors

Joel N. Hirschhorn
Joel N. Hirschhorn Boston Children's Hospital
Ruth J. F. Loos
Ruth J. F. Loos University of Copenhagen
Kari Stefansson
Kari Stefansson deCODE Genetics (Iceland)
Unnur Thorsteinsdottir
Unnur Thorsteinsdottir deCODE Genetics (Iceland)
Tamara B. Harris
Tamara B. Harris National Institutes of Health
Mary F. Feitosa
Mary F. Feitosa Washington University in St. Louis
Erik Ingelsson
Erik Ingelsson Stanford University
Caroline S. Fox
Caroline S. Fox MSD (United States)
Nicholas J. Wareham
Nicholas J. Wareham University of Cambridge

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