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David S. Leake

D-Index & Metrics

Biology and Biochemistry

D-Index
43
Citations
9684
World Ranking
19351
National Ranking
1498

David S. Leake publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where David S. Leake sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 139 publications — 21st percentile

21% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

David S. Leake D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David S. Leake sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 43 D-Index — 1st percentile

1% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

David S. Leake is affiliated with the University of Reading in the United Kingdom. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with primary focuses in subfields such as Biochemistry, Immunology, Molecular Biology, Surgery, and Clinical Biochemistry.

Their published work covers a variety of scientific topics, notably:

  • Antioxidant Activity and Oxidative Stress
  • Advanced Glycation End Products research
  • Drug Transport and Resistance Mechanisms
  • Biomedical Research and Pathophysiology
  • Peroxisome Proliferator-Activated Receptors
  • Cholesterol and Lipid Metabolism
  • Lipoproteins and Cardiovascular Health

David S. Leake has contributed to several scientific papers recently, including:

  • "Cysteamine Decreases Low-Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low-Density Lipoprotein Receptor-Deficient Mice" (2021), published in the Journal of the American Heart Association
  • "Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment" (2021), published in Frontiers in Immunology
  • "Vitamins E and C do not effectively inhibit low density lipoprotein oxidation by ferritin at lysosomal pH" (2021), published in Free Radical Research
  • "Effect of vitamin E on low density lipoprotein oxidation at lysosomal pH" (2020), published in Free Radical Research
  • "Effects of lysosomal low-density lipoprotein oxidation by ferritin on macrophage function" (2022), published in Free Radical Research

Their frequent co-authors include:

  • Tom Houben
  • Tulasi Yadati
  • Ronit Shiri-Sverdlov
  • Oluwatosin O. Ojo
  • Hadeel K. M. Alboaklah

In terms of publication venues, David S. Leake most often publishes in:

  • Free Radical Research
  • Journal of the American Heart Association
  • Frontiers in Immunology
  • Biomedicines
  • Innate Immunity

Best Publications

  • Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids

    Urs P. Steinbrecher;Sampath Parthasarathy;David S. Leake;Joseph L. Witztum

  • Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages.

    Catherine V. de Whalley;Sara M. Rankin;J.Robin S. Hoult;Wendy Jessup;Wendy Jessup

  • Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor.

    Colin H. Macphee;Kitty E. Moores;Helen F. Boyd;Dash Dhanak

  • Role of Nrf2 in the Regulation of CD36 and Stress Protein Expression in Murine Macrophages Activation by Oxidatively Modified LDL and 4-Hydroxynonenal

    Tetsuro Ishii;Ken Itoh;Emilio Ruiz;David S. Leake

  • α-tocopherol consumption during low-density-lipoprotein oxidation

    W Jessup;S M Rankin;C V De Whalley;J R S Hoult

  • In Vitro Antioxidant Activity of Coffee Compounds and Their Metabolites

    José Ángel Gómez-Ruiz;David S. Leake;Jennifer M. Ames

  • The oxidative modification of low-density lipoproteins by macrophages.

    D S Leake;S M Rankin

  • Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men

    Sabine Tricon;Graham C Burdge;Emma L Jones;Jennifer J Russell

  • Prooxidant and antioxidant properties of human serum ultrafiltrates toward LDL: important role of uric acid.

    Rebecca A. Patterson;Elizabeth T.M. Horsley;David S. Leake

  • Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment?

    Charles J.J Alderman;Peter R Bunyard;Benjamin M Chain;John C Foreman

  • Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions

    David S. Leake

  • Vitamin C Protects Human Vascular Smooth Muscle Cells Against Apoptosis Induced by Moderately Oxidized LDL Containing High Levels of Lipid Hydroperoxides

    Richard C. M. Siow;Justin P. Richards;Kevin C. Pedley;David S. Leake

  • Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses

    Elizabeth C. Leigh-Firbank;Anne M. Minihane;David S. Leake;John W. Wright

  • Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2.

    Anila A. Anwar;Francois Y.L. Li;David S. Leake;Tetsuro Ishii

  • Inhibition of lipoprotein-associated phospholipase A2 diminishes the death-inducing effects of oxidised LDL on human monocyte-macrophages.

    Keri L.H. Carpenter;Ian F. Dennis;Iain R. Challis;David P. Osborn

  • Practical Approaches to Low Density Lipoprotein Oxidation: Whys, Wherefores and Pitfalls*

    Catherine Rice-evans;David Leake;K. Richard Bruckdorfer;Anthony T. Diplock

  • Acidic pH enables caeruloplasmin to catalyse the modification of low‐density lipoprotein

    David J. Lamb;David S. Leake

  • Transition metal ions within human atherosclerotic lesions can catalyse the oxidation of low density lipoprotein by macrophages

    David J. Lamb;Malcolm J. Mitchinson;David S. Leake

  • Low Density Lipoprotein Undergoes Oxidation Within Lysosomes in Cells

    Yichuan Wen;David Sidney Leake

  • Induction of the antioxidant stress proteins heme oxygenase-1 and MSP23 by stress agents and oxidised LDL in cultured vascular smooth muscle cells

    Richard C.M. Siow;Tetsuro Ishii;Hideyo Sato;Hideyo Sato;Shigeru Taketani

Frequent Co-Authors

Catherine Rice-Evans
Catherine Rice-Evans King's College London
Timothy J. Peters
Timothy J. Peters University of Bristol
Wendy Jessup
Wendy Jessup Concord Repatriation General Hospital
Tetsuro Ishii
Tetsuro Ishii University of Tsukuba
Shiro Bannai
Shiro Bannai University of Tsukuba
Parveen Yaqoob
Parveen Yaqoob University of Reading
Jeremy D. Pearson
Jeremy D. Pearson King's College London
Benjamin M. Chain
Benjamin M. Chain University College London
Philip C. Calder
Philip C. Calder University of Southampton
David R. Katz
David R. Katz University College London

External Links

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Related Online Degrees & Career Pathways

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These online pathways allow you to specialize and advance your career while building upon the strong scientific background from biology and biochemistry studies.

Best Scientists Citing David S. Leake

Sampath Parthasarathy

Sampath Parthasarathy

University of Central Florida

Publications: 51

Daniel Steinberg

Daniel Steinberg

University of California, San Diego

Publications: 32

Michael Aviram

Michael Aviram

Technion – Israel Institute of Technology

Publications: 31

Joseph L. Witztum

Joseph L. Witztum

University of California, San Diego

Publications: 30

Hermann Esterbauer

Hermann Esterbauer

University of Graz

Publications: 27

Catherine Rice-Evans

Catherine Rice-Evans

King's College London

Publications: 24

Roger T. Dean

Roger T. Dean

Western Sydney University

Publications: 24

Victor M. Darley-Usmar

Victor M. Darley-Usmar

University of Alabama at Birmingham

Publications: 23

Wendy Jessup

Wendy Jessup

Concord Repatriation General Hospital

Publications: 23

Roland Stocker

Roland Stocker

The Heart Research Institute

Publications: 22

Urs P. Steinbrecher

Urs P. Steinbrecher

University of British Columbia

Publications: 22

Masayuki Yamamoto

Masayuki Yamamoto

Tohoku University

Publications: 22

Alexander N. Orekhov

Alexander N. Orekhov

Institute for Atherosclerosis Research

Publications: 22

Guy M. Chisolm

Guy M. Chisolm

Cleveland Clinic

Publications: 20

Barry Halliwell

Barry Halliwell

National University of Singapore

Publications: 20

Balz Frei

Balz Frei

Boston University

Publications: 18

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