David P. Knox

Best Publications

• Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

  John R. Grainger;Katie A. Smith;James P. Hewitson;Henry J. McSorley

  560
  Citations

• Digestive proteases of blood-feeding nematodes

  Angela L. Williamson;Paul J. Brindley;David P. Knox;Peter J. Hotez

  223
  Citations

• The nature and prospects for gut membrane proteins as vaccine candidates for Haemonchus contortus and other ruminant trichostrongyloids.

  David P. Knox;Diane L. Redmond;George F. Newlands;Philip J. Skuce

  197
  Citations

• RNA interference in parasitic helminths: current situation, potential pitfalls and future prospects.

  Peter Geldhof;Aline Visser;D Clark;G Saunders

  186
  Citations

• Testing the efficacy of RNA interference in Haemonchus contortus.

  Peter Geldhof;Linda Murray;Annabelle Couthier;John S. Gilleard

  167
  Citations

• Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative.

  Peter J Hotez;Bin Zhan;Jeffrey M Bethony;Alex Loukas

  160
  Citations

• RNA interference in parasitic nematodes of animals: a reality check?

  David P. Knox;Peter Geldhof;Aline Visser;Collette Britton

  137
  Citations

• Vaccination of calves against Ostertagia ostertagi with cysteine proteinase enriched protein fractions

  Peter Geldhof;Edwin Claerebout;D Knox;Isabel Vercauteren

  120
  Citations

• Proteinases released by the parasitic larval stages of Ascaris suum, and their inhibition by antibody

  David P. Knox;Malcolm W. Kennedy

  111
  Citations

• Molecular cloning and characterization of gut-derived cysteine proteinases associated with a host protective extract from Haemonchus contortus.

  P. J. Skuce;D. L. Redmond;S. Liddell;E. M. Stewart

  109
  Citations

• Vaccination against gastrointestinal nematode parasites of ruminants using gut-expressed antigens

  Unknown

  108
  Citations

• Molecular cloning and characterisation of a putative aspartate proteinase associated with a gut membrane protein complex from adult Haemonchus contortus.

  Unknown

  104
  Citations

• Cloning and characterization of a microsomal aminopeptidase from the intestine of the nematode Haemonchus contortus.

  Unknown

  104
  Citations

• Factors affecting susceptibility to RNA interference in Haemonchus contortus and in vivo silencing of an H11 aminopeptidase gene.

  Unknown

  100
  Citations

• Development of vaccines against gastrointestinal nematodes

  Unknown

  97
  Citations

• Molecular cloning and characterisation of a developmentally regulated putative metallopeptidase present in a host protective extract of Haemonchus contortus

  Unknown

  97
  Citations

• Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortus.

  Unknown

  90
  Citations

• Efficacy and specificity of RNA interference in larval life-stages of Ostertagia ostertagi.

  A. Visser;P. Geldhof;V. De Maere;D. P. Knox

  87
  Citations

• The contribution of molecular biology to the development of vaccines against nematode and trematode parasites of domestic ruminants.

  David P Knox;Diane L Redmond;Philip J Skuce;George F.J Newlands

  87
  Citations

• daf-7-related TGF-beta homologues from Trichostrongyloid nematodes show contrasting life-cycle expression patterns.

  Henry J McSorley;John R Grainger;Yvonne Harcus;Janice Murray

  86
  Citations