Danilo A. Tagle

Overview

Best Publications

• A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

  Marcy E. MacDonald;Christine M. Ambrose;Mabel P. Duyao;Richard H. Myers

  7760
  Citations

• A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

  M Shah;N Datson;L Srinidhi;VP Stanton

  4892
  Citations

• A SINGLE ATAXIA TELANGIECTASIA GENE WITH A PRODUCT SIMILAR TO PI-3 KINASE

  Kinneret Savitsky;Anat Bar-Shira;Shlomit Gilad;Galit Rotman

  3708
  Citations

• Atm-deficient mice: a paradigm of ataxia telangiectasia.

  Carrolee Barlow;Shinji Hirotsune;Richard Paylor;Marek Liyanage

  1805
  Citations

• Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.

  Eugene D. Carstea;Jill A. Morris;Katherine G. Coleman;Stacie K. Loftus

  1751
  Citations

• Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.

  Stacie K. Loftus;Jill A. Morris;Eugene D. Carstea;Jessie Z. Gu

  917
  Citations

• The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

  Kinneret Savitsky;Sharon Sfez;Danilo A. Tagle;Yael Ziv

  695
  Citations

• Organs-on-chips: into the next decade

  Lucie A. Low;Christine Mummery;Christine Mummery;Brian R. Berridge;Christopher P. Austin

  643
  Citations

• Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues.

  Theresa V. Strong;Danilo A. Tagle;John M. Valdes;Lawrence W. Elmer

  543
  Citations

• Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA

  P. Hemachandra Reddy;Maya Williams;Vinod Charles;Lisa Garrett

  508
  Citations

• Embryonic epsilon and gamma globin genes of a prosimian primate (Galago crassicaudatus). Nucleotide and amino acid sequences, developmental regulation and phylogenetic footprints

  Danilo A. Tagle;Ben F. Koop;Morris Goodman;Jerry L. Slightom;Jerry L. Slightom

  498
  Citations

• TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

  Dwight M Morrow;Danilo A Tagle;Yosef Shiloh;Francis S Collins

  486
  Citations

• Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

  Ulziibat Shirendeb;Arubala P. Reddy;Maria Manczak;Marcus J. Calkins

  411
  Citations

• Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.

  Manho Kim;H. S. Lee;Genevieve LaForet;Charmian McIntyre

  352
  Citations

• Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I

  Carrolee Barlow;Marek Liyanage;Peter B. Moens;Madalina Tarsounas

  338
  Citations

• Phenylketonuria Scientific Review Conference: state of the science and future research needs.

  Kathryn M. Camp;Melissa A. Parisi;Phyllis B. Acosta;Gerard T. Berry

  323
  Citations

• Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease

  G A Laforet;E Sapp;K Chase;C McIntyre

  315
  Citations

• Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing.

  Uwe Marx;Tommy B Andersson;Anthony Bahinski;Mario Beilmann

  304
  Citations

• Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways

  Carrolee Barlow;Kevin D. Brown;Chu Xia Deng;Danilo A. Tagle

  260
  Citations

• Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

  Qian Han;Tao Cai;Danilo A. Tagle;Jianyong Li

  253
  Citations