Charles F. B. Holmes

Overview

Best Publications

• Okadaic acid: a new probe for the study of cellular regulation.

  Philip Cohen;Charles F.B. Holmes;Yasumasa Tsukitani

  1772
  Citations

• Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell–Induced Apoptosis

  Bruce Motyka;Gregory Korbutt;Michael J Pinkoski;Jeffrey A Heibein

  548
  Citations

• Adsorption of microcystin-LR by activated carbon and removal in full scale water treatment

  Timothy W Lambert;Charles F.B Holmes;Steve E Hrudey

  299
  Citations

• Motuporin, A Potent Protein Phosphatase Inhibitor Isolated from the Papua New Guinea Sponge Theonella swinhoei Gray

  E.Dilip de Silva;David E. Williams;Raymond J. Andersen;Heide Klix

  288
  Citations

• Chemical and biological evidence links microcystins to salmon ‘netpen liver disease’

  Raymond J. Andersen;Hue A. Luu;Dawn Z.X. Chen;Charles F.B. Holmes

  271
  Citations

• A molecular basis for different interactions of marine toxins with protein phosphatase-1. Molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A.

  John R. Bagu;Brian D. Sykes;Marcia M. Craig;Charles F. B. Holmes

  228
  Citations

• Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1.

  Jason T. Maynes;Katherine S. Bateman;Maia M. Cherney;Amit K. Das

  216
  Citations

• Microcystin-LR concentration in aquatic food web compartments from lakes of varying trophic status

  B. G. Kotak;R. W. Zurawell;E. E. Prepas;C. F. B. Holmes

  214
  Citations

• Molecular mechanisms underlying the interaction of motuporin and microcystins with type-1 and type-2A protein phosphatases

  M. Craig;Hue Anh Luu;T. L. Mccready;D. Williams

  212
  Citations

• Bioaccumulation and clearance of microcystins from salt water mussels, mytilus edulis, and in vivo evidence for covalently bound microcystins in mussel tissues

  David E. Williams;Sheila C. Dawe;Michael L. Kent;Raymond J. Andersen

  207
  Citations

• Regulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation.

  Meltem Sariahmetoglu;Bryan D. Crawford;Hernando Leon;Jolanta Sawicka

  199
  Citations

• The adsorption of microcystin-LR by natural clay particles.

  Robert J. Morris;David E. Williams;Hue A. Luu;Charles F.B. Holmes

  199
  Citations

• Evidence for a Covalently Bound Form of Microcystin-LR in Salmon Liver and Dungeness Crab Larvae

  David E. Williams;Marcia Craig;Sheila C. Dawe;Michael L. Kent

  157
  Citations

• Accumulation and elimination of cyanobacterial hepatotoxins by the freshwater clam Anodonta grandis simpsoniana

  E. E. Prepas;B. G. Kotak;L. M. Campbell;J. C. Evans

  145
  Citations

• Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins.

  John F. Dawson;Charles F. B. Holmes

  144
  Citations

• The protein phosphatases involved in cellular regulation. Primary structure of inhibitor-2 from rabbit skeletal muscle.

  Holmes Cf;Campbell Dg;Caudwell Fb;Aitken A

  142
  Citations

• Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry.

  Linda Poulter;Siau-Gek Ang;Bradford W. Gibson;Dudley H. Williams

  134
  Citations

• 14C-Labeled microcystin-LR administered to Atlantic salmon via intraperitoneal injection provides in vivo evidence for covalent binding of microcystin-LR in salmon livers

  David E. Williams;Marcia Craig;Sheila C. Dawe;Michael L. Kent

  128
  Citations

• Comparison of liquid chromatography/mass spectrometry, ELISA, and phosphatase assay for the determination of microcystins in blue-green algae products

  James F Lawrence;Barbara Niedzwiadek;Cathie Menard;Benjamin P Y Lau

  127
  Citations

• Protein phosphatase inhibitor-1 and inhibitor-2 from rabbit skeletal muscle.

  Philip Cohen;J. Gordon Foulkes;Charles F.B. Holmes;Gillian A. Nimmo

  127
  Citations