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Biology and Biochemistry

D-Index
55
Citations
11831
World Ranking
14977
National Ranking
6266

Overview

Ashley M. Vaughan is affiliated with Seattle Children's Hospital in the United States and has a research focus predominantly in the fields of Medicine, Immunology, and Microbiology. Their work spans several specialized subfields including Public Health, Environmental and Occupational Health, Immunology, Molecular Biology, Epidemiology, and Oncology.

Their research primarily addresses topics related to Malaria Research and Control, Mosquito-borne Diseases and Control, Invertebrate Immune Response Mechanisms, Trypanosoma Species Research and Implications, Drug Transport and Resistance Mechanisms, Computational Drug Discovery Methods, and Insect Resistance and Genetics.

Among recent publications authored or co-authored by Ashley M. Vaughan are:

  • Plasmodium vivax Latent Liver Stage Infection and Relapse: Biological Insights and New Experimental Tools (2021, Annual Review of Microbiology)
  • Chloroquine Resistance Evolution in Plasmodium falciparum Is Mediated by the Putative Amino Acid Transporter AAT1 (2023, Nature Microbiology)
  • A Replication-Competent Late Liver Stage-Attenuated Human Malaria Parasite (2020, JCI Insight)
  • A Genetically Engineered Plasmodium falciparum Parasite Vaccine Provides Protection from Controlled Human Malaria Infection (2022, Science Translational Medicine)
  • Sporozoite Immunization: Innovative Translational Science to Support the Fight Against Malaria (2023, Expert Review of Vaccines)

Frequent co-authors collaborating with Vaughan include:

  • Stefan H. I. Kappe (32 publications)
  • Sudhir Kumar (25 publications)
  • Meseret T. Haile (18 publications)
  • Michael T. Ferdig (15 publications)
  • Ian H. Cheeseman (13 publications)

Vaughan has published extensively across several venues, with the most frequent publication outlets being:

  • bioRxiv (Cold Spring Harbor Laboratory) - 15 publications
  • Nature Microbiology - 2 publications
  • EMBO Molecular Medicine - 2 publications
  • Science - 2 publications
  • Trends in Parasitology - 2 publications

Best Publications

  • The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

    Richard M. Lawn;David P. Wade;Michael R. Garvin;Xingbo Wang

  • ATP-Binding Cassette Cholesterol Transporters and Cardiovascular Disease

    John F. Oram;Andrew T. M. Vaughan

  • Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

    Ashley M Vaughan;Matthew T O'Neill;Alice S Tarun;Nelly Camargo

  • Malaria Parasite Development in the Mosquito and Infection of the Mammalian Host

    Ahmed S.I. Aly;Ashley M. Vaughan;Stefan H.I. Kappe

  • The Anopheles gambiae detoxification chip: A highly specific microarray to study metabolic-based insecticide resistance in malaria vectors

    Jean-Philippe David;Clare Strode;John Vontas;Dimitra Nikou

  • ABCA1-mediated transport of cellular cholesterol and phospholipids to HDL apolipoproteins.

    John F. Oram;Ashley M. Vaughan

  • ABCG1 Redistributes Cell Cholesterol to Domains Removable by High Density Lipoprotein but Not by Lipid-depleted Apolipoproteins

    Ashley M. Vaughan;John F. Oram

  • ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL

    Ashley M. Vaughan;John F. Oram

  • The Macrophage Cholesterol Exporter ABCA1 Functions as an Anti-inflammatory Receptor

    Chongren Tang;Yuhua Liu;Peter S. Kessler;Ashley M. Vaughan

  • That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda

    Stefan H. I. Kappe;Stefan H. I. Kappe;Ashley M. Vaughan;Justin A. Boddey;Alan F. Cowman

  • Superior Antimalarial Immunity after Vaccination with Late Liver Stage-Arresting Genetically Attenuated Parasites

    Noah S. Butler;Nathan W. Schmidt;Ashley M. Vaughan;Ahmed S. Aly

  • Complete Plasmodium falciparum liver-stage development in liver-chimeric mice

    Ashley M. Vaughan;Sebastian A. Mikolajczak;Elizabeth M. Wilson;Markus Grompe

  • ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions.

    Ashley M. Vaughan;John F. Oram

  • Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics.

    Kristian E. Swearingen;Scott E. Lindner;Scott E. Lindner;Lirong Shi;Melanie J. Shears

  • ATP-binding cassette transporter A1 expression disrupts raft membrane microdomains through its ATPase-related functions.

    Yves D. Landry;Maxime Denis;Shilpi Nandi;Stephanie Bell

  • Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice

    Sebastian A. Mikolajczak;Ashley M. Vaughan;Niwat Kangwanrangsan;Wanlapa Roobsoong

  • Interferon-mediated innate immune responses against malaria parasite liver stages.

    Jessica L. Miller;Brandon K. Sack;Michael Baldwin;Ashley M. Vaughan

  • Total and putative surface proteomics of malaria parasite salivary gland sporozoites

    Scott E. Lindner;Kristian E. Swearingen;Anke Harupa;Anke Harupa;Ashley M. Vaughan

  • ATP-binding Cassette Transporter A1 Mediates Cellular Secretion of α-Tocopherol

    John F. Oram;Ashley M. Vaughan;Roland Stocker

  • Malaria parasite pre-erythrocytic stage infection: gliding and hiding.

    Ashley M. Vaughan;Ahmed S.I. Aly;Stefan H.I. Kappe;Stefan H.I. Kappe

Frequent Co-Authors

Stefan H. I. Kappe
Stefan H. I. Kappe University of Washington
François Nosten
François Nosten MORU Mahidol Oxford Tropical Medicine Research Unit
John F. Oram
John F. Oram University of Washington
Tim J. Anderson
Tim J. Anderson Texas Biomedical Research Institute
Jetsumon Sattabongkot
Jetsumon Sattabongkot Mahidol University
Robert L. Moritz
Robert L. Moritz Institute for Systems Biology
James G. Kublin
James G. Kublin Fred Hutchinson Cancer Research Center
Robert W. Sauerwein
Robert W. Sauerwein Radboud University
Photini Sinnis
Photini Sinnis Johns Hopkins University

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