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Biology and Biochemistry

D-Index
59
Citations
19692
World Ranking
12287
National Ranking
877

Overview

Antje Sucker is affiliated with the University of Duisburg-Essen in Germany and has an extensive record of research publications primarily in the fields of medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their work is particularly concentrated on oncology, immunology, molecular biology, and cancer research.

The scientist's research topics focus notably on melanoma and MAPK pathways, immunotherapy and immune responses, cutaneous melanoma detection and management, cancer immunotherapy and biomarkers, CAR-T cell therapy research, cancer genomics and diagnostics, as well as polyomavirus and related diseases.

Frequent publication venues for Antje Sucker include:

  • European Journal of Cancer
  • Annals of Oncology
  • Clinical Cancer Research
  • Journal for ImmunoTherapy of Cancer
  • Cancers

Notable recent papers authored or co-authored by Sucker include:

  • Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma, 2020, Annals of Oncology
  • Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy, 2020, Journal of Clinical Investigation
  • Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell Carcinoma, 2020, Clinical Cancer Research
  • Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma, 2023, Nature Cancer
  • Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy, 2020, Journal for ImmunoTherapy of Cancer

Frequent co-authors collaborating with Antje Sucker are:

  • Dirk Schadendorf
  • Elisabeth Livingstone
  • Lisa Zimmer
  • Eva Hadaschik
  • Selma Ugurel

Overall, Antje Sucker's academic contributions emphasize exploring mechanisms and biomarkers related to immunotherapy and melanoma, reflected in their publication record and collaborative efforts.

Best Publications

  • Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

    Eliezer M. Van Allen;Eliezer M. Van Allen;Diana Miao;Diana Miao;Bastian Schilling;Sachet A. Shukla;Sachet A. Shukla

  • Genomic Classification of Cutaneous Melanoma

    Rehan Akbani;Kadir C. Akdemir;B. Arman Aksoy;Monique Albert

  • TERT Promoter Mutations in Familial and Sporadic Melanoma

    Susanne Horn;Adina Figl;P. Sivaramakrishna Rachakonda;Christine Fischer

  • Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

    David Liu;David Liu;Bastian Schilling;Bastian Schilling;Derek Liu;Derek Liu;Antje Sucker

  • The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma

    Eliezer M. Van Allen;Eliezer M. Van Allen;Nikhil Wagle;Nikhil Wagle;Antje Sucker;Daniel J. Treacy

  • Melanoma genome sequencing reveals frequent PREX2 mutations

    Michael F. Berger;Michael F. Berger;Eran Hodis;Timothy P. Heffernan;Timothy P. Heffernan;Yonathan Lissanu Deribe

  • Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG

    D. Schadendorf;S. Ugurel;B. Schuler-Thurner;F.O. Nestle

  • Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.

    Keith S Hoek;Natalie C Schlegel;Patricia Brafford;Antje Sucker

  • Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab.

    Alexander Martens;Kilian Wistuba-Hamprecht;Marnix H Geukes Foppen;Jianda Yuan

  • RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors

    Patrick A. Oberholzer;Damien Kee;Damien Kee;Piotr Dziunycz;Antje Sucker

  • NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

    Tadepally Lakshmikanth;Shannon Burke;Talib Hassan Ali;Silvia Kimpfler

  • Myeloid Cells and Related Chronic Inflammatory Factors as Novel Predictive Markers in Melanoma Treatment with Ipilimumab.

    Christoffer Gebhardt;Alexandra Sevko;Huanhuan Jiang;Huanhuan Jiang;Ramtin Lichtenberger

  • Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms.

    Douglas B. Johnson;Alexander M. Menzies;Lisa Zimmer;Zeynep Eroglu

  • Lack of clinical efficacy of imatinib in metastatic melanoma

    S Ugurel;R Hildenbrand;A Zimpfer;P La Rosée

  • Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1- or Melan-A–Specific T Cells

    Benjamin Weide;Alexander Martens;Henning Zelba;Christina Stutz

  • Angiopoietin-2 Levels Are Associated with Disease Progression in Metastatic Malignant Melanoma

    Iris Helfrich;Lutz Edler;Antje Sucker;Markus Thomas;Markus Thomas

  • TERT Promoter Mutation Status as an Independent Prognostic Factor in Cutaneous Melanoma

    Klaus G. Griewank;Rajmohan Murali;Joan Anton Puig-Butille;Bastian Schilling

  • Atypical Melanocytic Proliferations and New Primary Melanomas in Patients With Advanced Melanoma Undergoing Selective BRAF Inhibition

    Lisa Zimmer;Uwe Hillen;Elisabeth Livingstone;Mario E. Lacouture

  • Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

    David Liu;Bastian Schilling;Derek Liu;Antje Sucker

  • Melanoma genome sequencing reveals frequent PREX2 mutations

    Eric S. Lander;Michael F. Berger;Eran Hodis;Timothy P. Heffernan

Frequent Co-Authors

Dirk Schadendorf
Dirk Schadendorf University of Duisburg-Essen
Jürgen C. Becker
Jürgen C. Becker University of Duisburg-Essen
Jochen Utikal
Jochen Utikal German Cancer Research Center
Ralf Gutzmer
Ralf Gutzmer Hannover Medical School
Levi A. Garraway
Levi A. Garraway Roche (United States)
Eliezer M. Van Allen
Eliezer M. Van Allen Harvard University
Richard A. Scolyer
Richard A. Scolyer Royal Prince Alfred Hospital
Kari Hemminki
Kari Hemminki Charles University
Julia Newton-Bishop
Julia Newton-Bishop University of Leeds
Christian U. Blank
Christian U. Blank Antoni van Leeuwenhoek Hospital

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