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Animal Science and Veterinary

D-Index
34
Citations
4549
World Ranking
1859
National Ranking
83

Overview

Anne Lespine is affiliated with the Federal University of Toulouse Midi-Pyrénées in France. Their research spans veterinary and medical fields, with a particular focus on parasitology, infectious diseases, and animal science.

Lespine's work covers a range of topics, including:

  • Helminth infection and control
  • Parasites and host interactions
  • Coccidia and coccidiosis research
  • Parasitic diseases research and treatment
  • Parasite biology and host interactions
  • Dermatological diseases and infestations
  • Drug transport and resistance mechanisms

Their research publications include studies such as:

  • "Serious Ivermectin Toxicity and Human ABCB1 Nonsense Mutations" (2020) published in the New England Journal of Medicine
  • "First report of multiple resistance to eprinomectin and benzimidazole in Haemonchus contortus on a dairy goat farm in France" (2020) published in Parasitology International
  • "Oral ivermectin for a scabies outbreak in a long-term care facility: potential value in preventing COVID-19 and associated mortality" (2021) from the British Journal of Dermatology
  • "Effect of sainfoin (Onobrychis viciifolia) on cyathostomin eggs excretion, larval development, larval community structure and efficacy of ivermectin treatment in horses" (2022) published in Parasitology
  • "P-glycoprotein (ABCB1) is involved in vitamin K efflux" (2020) published in Food Chemistry

Frequent coauthors collaborating with Lespine include:

  • Mélanie Alberich
  • Philippe Jacquiet
  • Clara Blancfuney
  • Jean-François Sutra
  • Sophie Jouffroy

Lespine's publications frequently appear in journals such as:

  • Journal of Veterinary Pharmacology and Therapeutics
  • Parasitology
  • Scientific Reports
  • Trends in Parasitology
  • Parasites & Vectors

Their academic work predominantly addresses research areas related to small animals within veterinary science, with a focus on parasitological and infectious disease challenges affecting animal health and treatment resistance.

Best Publications

  • Moxidectin and the avermectins: Consanguinity but not identity.

    Roger Prichard;Cécile Ménez;Anne Lespine;Anne Lespine

  • P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance

    Anne Lespine;Cécile Ménez;Catherine Bourguinat;Roger K. Prichard

  • Interaction of macrocyclic lactones with P-glycoprotein: Structure–affinity relationship

    Anne Lespine;Solenne Martin;Jacques Dupuy;Alain Roulet

  • Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions

    Andrew C. Kotze;Peter W. Hunt;Philip John Skuce;Georg von Samson-Himmelstjerna

  • Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1

    Cédric Le May;Jean Mathieu Berger;Anne Lespine;Bruno Pillot

  • Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin

    J Dupuy;G Larrieu;J.F Sutra;A Lespine

  • Interaction of ivermectin with multidrug resistance proteins (MRP1, 2 and 3).

    Anne Lespine;Jacques Dupuy;Stéphane Orlowski;Tünde Nagy

  • ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics

    Anne Lespine;Michel Alvinerie;Jozef Vercruysse;Roger K. Prichard

  • P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus.

    D. J. Bartley;H. McALLISTER;Y. Bartley;J. Dupuy

  • Role of P-glycoprotein in the disposition of macrocyclic lactones: A comparison between ivermectin, eprinomectin, and moxidectin in mice.

    Solange Kiki-Mvouaka;Cécile Ménez;Christiane Borin;Faouri Lyazrhi

  • Relative neurotoxicity of ivermectin and moxidectin in Mdr1ab (-/-) mice and effects on mammalian GABA(A) channel activity.

    Cécile Ménez;Jean François Sutra;Jean François Sutra;Roger Prichard;Anne Lespine;Anne Lespine

  • Influence of the route of administration on efficacy and tissue distribution of ivermectin in goat.

    Anne Lespine;Michel Alvinerie;Jean-François Sutra;Isabelle Pors

  • Ivermectin induces P-glycoprotein expression and function through mRNA stabilization in murine hepatocyte cell line

    Cécile Ménez;Laïla Mselli-Lakhal;Magali Foucaud-Vignault;Patrick Balaguer

  • Preclinical Study of Single-Dose Moxidectin, a New Oral Treatment for Scabies: Efficacy, Safety, and Pharmacokinetics Compared to Two-Dose Ivermectin in a Porcine Model.

    Charlotte Bernigaud;Charlotte Bernigaud;Fang Fang;Katja Fischer;Anne Lespine

  • Interaction of anthelmintic drugs with P-glycoprotein in recombinant LLC-PK1-mdr1a cells.

    Jacques Dupuy;Michel Alvinerie;Cecile Ménez;Anne Lespine

  • Serious Ivermectin Toxicity and Human ABCB1 Nonsense Mutations.

    Eloise Baudou;Anne Lespine;Geneviève Durrieu;François André

  • Ketoconazole increases the plasma levels of ivermectin in sheep.

    Michel Alvinerie;Jacques Dupuy;Solange Kiki-Mvouaka;Jean-François Sutra

  • Interaction of macrocyclic lactones with the multidrug transporters: the bases of the pharmacokinetics of lipid-like drugs.

    A. Lespine;J. Dupuy;M. Alvinerie;C. Comera

  • The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes

    Cécile Ménez;Mélanie Alberich;Elise Courtot;Fabrice Guegnard

  • Eprinomectin in goat: assessment of subcutaneous administration.

    A Lespine;J F Sutra;J Dupuy;M Alvinerie

  • The comparative serum disposition kinetics of subcutaneous administration of doramectin, ivermectin and moxidectin in the Australian Merino sheep

    S. Barber;V. Bowles;A. Lespine;M. Alvinerie

Frequent Co-Authors

Michel Alvinerie
Michel Alvinerie INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Roger K. Prichard
Roger K. Prichard McGill University
Jean-François Sutra
Jean-François Sutra INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Jacques Guillot
Jacques Guillot École nationale vétérinaire d'Alfort
Olivier Chosidow
Olivier Chosidow Université Paris Cité
Patrick Borel
Patrick Borel Aix-Marseille University
Fang Fang
Fang Fang North China Electric Power University
Kathelijn Fischer
Kathelijn Fischer Utrecht University
Hervé Hoste
Hervé Hoste Federal University of Toulouse Midi-Pyrénées
Christophe Chartier
Christophe Chartier INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement

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Related Online Degrees & Career Pathways

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