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Biology and Biochemistry

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41
Citations
10717
World Ranking
19530
National Ranking
7958

Overview

Yukio Saijoh is a researcher affiliated with the University of Utah in the United States. Their work primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions to medicine. Saijoh's research covers a range of subfields including molecular biology, physiology, cell biology, epidemiology, and surgery.

The scientist's research topics include glycosylation and glycoproteins, adipose tissue and metabolism, proteoglycans and glycosaminoglycans, congenital heart defects, mitochondrial function and pathology, congenital heart disease studies, and tissue engineering and regenerative medicine.

Among recent publications are the following papers:

  • Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1, 2020, published in PLoS ONE
  • Metabolic engineering of non-pathogenic Escherichia coli strains for the controlled production of low molecular weight heparosan and size-specific heparosan oligosaccharides, 2020, published in Biochimica et Biophysica Acta (BBA) - General Subjects
  • PERM1 regulates energy metabolism in the heart via ERRα/PGC−1α axis, 2022, published in Frontiers in Cardiovascular Medicine
  • Visualizing antithrombin-binding 3-O-sulfated heparan sulfate motifs on cell surfaces, 2020, published in Chemical Communications
  • Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish, 2022, published in Communications Biology

Frequent coauthors in Saijoh's collaboration network include Balagurunathan Kuberan, Thirupura S. Shankar, Stavros G. Drakos, Junco S. Warren, and Jie Shi Chua.

Saijoh's work has appeared most often in the following publication venues:

  • Methods in molecular biology (3 publications)
  • PLoS ONE
  • Biochimica et Biophysica Acta (BBA) - General Subjects
  • Frontiers in Cardiovascular Medicine
  • Communications Biology

Best Publications

  • Determination of left–right patterning of the mouse embryo by artificial nodal flow

    Shigenori Nonaka;Hidetaka Shiratori;Yukio Saijoh;Hiroshi Hamada

  • lefty-1 Is Required for Left-Right Determination as a Regulator of lefty-2 and nodal

    Chikara Meno;Akihiko Shimono;Yukio Saijoh;Kenta Yashiro

  • Establishment of vertebrate left-right asymmetry

    Hiroshi Hamada;Chikara Meno;Daisuke Watanabe;Yukio Saijoh

  • Left–right asymmetric expression of the TGFβ-family member lefty in mouse embryos

    Chikara Meno;Yukio Saijoh;Yukio Saijoh;Hideta Fujii;Hideta Fujii;Masako Ikeda

  • The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo

    Yasuo Sakai;Chikara Meno;Hideta Fujii;Jinsuke Nishino

  • Abnormal Nodal Flow Precedes Situs Inversus in iv and inv mice

    Yasushi Okada;Shigenori Nonaka;Yosuke Tanaka;Yukio Saijoh

  • Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo

    Masamichi Yamamoto;Yukio Saijoh;Aitana Perea-Gomez;Aitana Perea-Gomez;William Shawlot;William Shawlot

  • Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb.

    Kenta Yashiro;Xianling Zhao;Masayuki Uehara;Kimiyo Yamashita

  • Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: Their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos

    Chikara Meno;Yuzuru Ito;Yukio Saijoh;Youichi Matsuda

  • Left–Right Asymmetric Expression of lefty2 and nodal Is Induced by a Signaling Pathway that Includes the Transcription Factor FAST2

    Yukio Saijoh;Hitoshi Adachi;Rui Sakuma;Chang Yeol Yeo

  • Cloning of inv, a gene that controls left/right asymmetry and kidney development

    Toshio Mochizuki;Yukio Saijoh;Ken Tsuchiya;Yasuaki Shirayoshi

  • Notch signaling regulates left–right asymmetry determination by inducing Nodal expression

    Luke T. Krebs;Naomi Iwai;Shigenori Nonaka;Ian C. Welsh

  • Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2.

    Hidetaka Shiratori;Rui Sakuma;Minoru Watanabe;Hiromi Hashiguchi

  • The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse

    Masamichi Yamamoto;Chikara Meno;Yasuo Sakai;Hidetaka Shiratori

  • Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis.

    Jun K. Takeuchi;Makoto Ohgi;Kazuko Koshiba-Takeuchi;Hidetaka Shiratori

  • The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia.

    Daisuke Watanabe;Yukio Saijoh;Shigenori Nonaka;Genta Sasaki

  • GFRα3, a Component of the Artemin Receptor, Is Required for Migration and Survival of the Superior Cervical Ganglion

    Jinsuke Nishino;Kyoko Mochida;Yasuhisa Ohfuji;Takuya Shimazaki

  • Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis.

    Masatsugu Ema;Masanobu Morita;Shuntaro Ikawa;Masahiro Tanaka

  • Diffusion of Nodal Signaling Activity in the Absence of the Feedback Inhibitor Lefty2

    Chikara Meno;Jun Takeuchi;Rui Sakuma;Kazuko Koshiba-Takeuchi

  • Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos.

    Youhei Sakamoto;Kenshiro Hara;Masami Kanai-Azuma;Toshiyasu Matsui

Frequent Co-Authors

Hiroshi Hamada
Hiroshi Hamada RIKEN Center for Biosystems Dynamics Research
Gary C. Schoenwolf
Gary C. Schoenwolf University of Utah
Michael M. Shen
Michael M. Shen Columbia University
Masatsugu Ema
Masatsugu Ema Shiga University of Medical Science
Koji Tamura
Koji Tamura Tohoku University
Yoshiaki Fujii-Kuriyama
Yoshiaki Fujii-Kuriyama Tokyo Medical and Dental University
Janet Rossant
Janet Rossant University of Toronto
Michael J. Gambello
Michael J. Gambello Emory University
Osamu Gotoh
Osamu Gotoh Japanese Foundation For Cancer Research
Len A. Pennacchio
Len A. Pennacchio Lawrence Berkeley National Laboratory

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