World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
59
Citations
13046
World Ranking
10093
National Ranking
720

Overview

Tohru Koike is affiliated with Hiroshima University in Japan with a research focus spanning biochemistry, genetics, molecular biology, materials science, and chemistry. Their work addresses multiple interconnected scientific disciplines, particularly emphasizing molecular biology and materials chemistry at the subfield level.

The scientist's research concentrates on various topics, including:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Metal complexes synthesis and properties
  • Monoclonal and Polyclonal Antibodies Research
  • Advanced Proteomics Techniques and Applications
  • Advanced biosensing and bioanalysis techniques
  • Crystal structures of chemical compounds

Tohru Koike has published extensively in numerous scientific venues. Frequent publication venues include:

  • The Cambridge Structural Database
  • X-ray Structure Analysis Online
  • Journal of Electrophoresis
  • Journal of Proteomics
  • IUCrData

Some of their recent scientific papers are as follows:

  • "History of Phos-tag technology for phosphoproteomics", 2021, Journal of Proteomics
  • "Evaluation of four phosphopeptide enrichment strategies for mass spectrometry-based proteomic analysis", 2021, PROTEOMICS
  • "Protein-N-myristoylation-dependent phosphorylation of serine 13 of tyrosine kinase Lyn by casein kinase 1γ at the Golgi during intracellular protein traffic", 2020, Scientific Reports
  • "Identification of activity-based biomarkers for early-stage pancreatic tumors in blood using single-molecule enzyme activity screening", 2024, Cell Reports Methods
  • "Aqua(1,4,7,10-tetraazacyclododecane)zinc(II) bis(perchlorate)", 2021, IUCrData

Collaborations form a significant part of Koike's research output. Frequent coauthors include:

  • Emiko Kinoshita-Kikuta
  • Eiji Kinoshita
  • Yoshimi Ichimaru
  • Hiromasa Kurosaki
  • Koichi Kato

Best Publications

  • Phosphate-binding Tag, a New Tool to Visualize Phosphorylated Proteins

    Eiji Kinoshita;Emiko Kinoshita-Kikuta;Kei Takiyama;Tohru Koike

  • Recent development of zinc-fluorophores

    Eiichi Kimura;Tohru Koike

  • Separation and detection of large phosphoproteins using Phos-tag SDS-PAGE

    Eiji Kinoshita;Emiko Kinoshita-Kikuta;Tohru Koike

  • A zinc(II) complex of 1,5,9-triazacyclododecane ([12]aneN3) as a model for carbonic anhydrase

    Eiichi Kimura;Takeshi Shiota;Tohru Koike;Motoo Shiro

  • Roles of zinc(II) ion in phosphatases. A model study with zinc(II)-macrocyclic polyamine complexes

    Tohru Koike;Eiichi Kimura

  • A Tris(ZnII−1,4,7,10-tetraazacyclododecane) Complex as a New Receptor for Phosphate Dianions in Aqueous Solution

    Eiichi Kimura;Shin Aoki;Tohru Koike;Motoo Shiro

  • A NOVEL BIOMIMETIC ZINC(II)-FLUOROPHORE, DANSYLAMIDOETHYL-PENDANT MACROCYCLIC TETRAAMINE 1,4,7,10-TETRAAZACYCLODODECANE (CYCLEN)

    Tohru Koike;Tomohiko Watanabe;Shin Aoki;Eiichi Kimura

  • FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.

    Masamichi Ishiai;Hiroyuki Kitao;Hiroyuki Kitao;Hiroyuki Kitao;Agata Smogorzewska;Junya Tomida

  • Recognition of phosphate monoester dianion by an alkoxide-bridged dinuclear zinc(II) complex

    Eiji Kinoshita;Makoto Takahashi;Hironori Takeda;Motoo Shiro

  • The catalytic carboxyester hydrolysis by a new zinc(II) complex with an alcohol-pendant cyclen (1-(2-hydroxyethyl)-1,4,7,10-tetraazacyclododecane): A novel model for indirect activation of the serine nucleophile by zinc(II) in zinc enzymes

    Tohru Koike;Satoko Kajitani;Ikushi Nakamura;Eiichi Kimura

  • Novel Properties of Cooperative Dinuclear Zinc(II) Ions: The Selective Recognition of Phosphomonoesters and Their P−O Ester Bond Cleavage by a New Dinuclear Zinc(II) Cryptate

    Tohru Koike;Masaki Inoue;Eiichi Kimura, ,† and;Motoo Shiro

  • Kinetics and mechanism of the hydration of carbon dioxide and dehydration of bicarbonate catalyzed by a zinc (II) complex of 1,5,9-triazacyclododecane as a model for carbonic anhydrase

    Xiaoping Zhang;Rudi van Eldik;Tohru Koike;Eiichi Kimura

  • HYDROLYSIS OF LIPOPHILIC ESTERS CATALYZED BY A ZINC(II) COMPLEX OF A LONG ALKYL-PENDANT MACROCYCLIC TETRAAMINE IN MICELLAR SOLUTION

    Eiich Kimura;Hiroyuki Hashimoto;Tohru Koike

  • A macrocyclic zinc(II) fluorophore as a detector of apoptosis.

    Eiichi Kimura;Shin Aoki;Emiko Kikuta;Tohru Koike

  • PHOSPHODIESTER HYDROLYSIS BY A NEW ZINC(II) MACROCYCLIC TETRAAMINE COMPLEX WITH AN ALCOHOL PENDANT : ELUCIDATION OF THE ROLES OF SER-102 AND ZINC(II) IN ALKALINE PHOSPHATASE

    Eiichi Kimura;Yorimitsu Kodama;Tohru Koike;Motoo Shiro

  • Novel Recognition of Thymine Base in Double-Stranded DNA by Zinc(II)−Macrocyclic Tetraamine Complexes Appended with Aromatic Groups

    Emiko Kikuta;Mariko Murata;Naomi Katsube;Tohru Koike

  • The first anionic sulfonamide-binding zinc(II) complexes with a macrocyclic triamine: chemical verification of the sulfonamide inhibition of carbonic anhydrase

    Tohru Koike;Eiichi Kimura;Ikushi Nakamura;Yukie Hashimoto

  • Carboxyester Hydrolysis Promoted by a New Zinc(II) Macrocyclic Triamine Complex with an Alkoxide Pendant: A Model Study for the Serine Alkoxide Nucleophile in Zinc Enzymes

    Eiichi Kimura;Ikushi Nakamura;Tohru Koike;Mitsuhiko Shionoya

  • Detection and quantification of on-chip phosphorylated peptides by surface plasmon resonance imaging techniques using a phosphate capture molecule

    Kazuki Inamori;Motoki Kyo;Yoshiaki Nishiya;Yusuke Inoue

  • Mechanisms of water oxidation catalyzed by the cis,cis-[(bpy)2Ru(OH2)]2O4+ ion.

    Hiroshi Yamada;William F. Siems;Tohru Koike;James K. Hurst

Frequent Co-Authors

Eiichi Kimura
Eiichi Kimura Hiroshima University
Mitsuhiko Shionoya
Mitsuhiko Shionoya University of Tokyo
Motoo Shiro
Motoo Shiro Nagoya Institute of Technology
Yoichi Iitaka
Yoichi Iitaka University of Tokyo
Shin Aoki
Shin Aoki Tokyo University of Science
Yoshio Umezawa
Yoshio Umezawa University of Tokyo
Kazuaki Chayama
Kazuaki Chayama Hiroshima University
Hisashi Hirano
Hisashi Hirano Yokohama City University
Minoru Takata
Minoru Takata Kyoto University
Akira Tokumura
Akira Tokumura Yasuda Women's University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens doors to various related fields and career paths that can complement your scientific expertise. For those interested in legal aspects connected to chemistry, exploring types of paralegals can provide insights into specialized roles, such as patent law or environmental regulations.

Additionally, if you are considering expanding your credentials, looking into online criminal justice associate degree programs offers flexible options to blend legal knowledge with your scientific background. Understanding how much is criminal justice degree can help you plan your educational investments wisely when pursuing these interdisciplinary qualifications.

For a direct application of chemistry in the business world, a career as a pharmaceutical sales representative is worth considering. This pathway leverages your scientific knowledge while focusing on communication and sales skills. You can learn more about this field by reviewing the typical pharmaceutical sales salary and career paths available.

By exploring these related online degrees and career options, chemistry students can diversify their skills and enhance their job prospects in a competitive market.

Best Scientists Citing Tohru Koike

Trending Scientists

Recently Published Articles