World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
53
Citations
75014
World Ranking
3671
National Ranking
1591

Research.com Recognitions

  • 2003 - Fellow of Alfred P. Sloan Foundation

Overview

Todd M. Lowe is affiliated with the University of California, Santa Cruz in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, including significant contributions to Molecular Biology, Cancer Research, Oncology, Infectious Diseases, and Genetics.

Their work covers diverse topics with a focus on RNA biology and molecular mechanisms related to cancer and infectious diseases. Key topics of research include:

  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • RNA research and splicing
  • Cancer-related molecular mechanisms research
  • Genomics and phylogenetic studies
  • Peptidase inhibition and analysis
  • SARS-CoV-2 and COVID-19 research

Their recent publications demonstrate active involvement in RNA gene detection, structure prediction, and genomic research. Notable papers include:

  • "tRNAscan-SE 2.0: improved detection and functional classification of transfer RNA genes" (2021), published in Nucleic Acids Research
  • "RNAcentral 2021: secondary structure integration, improved sequence search and new member databases" (2020), published in Nucleic Acids Research
  • "R2DT is a framework for predicting and visualising RNA secondary structure using templates" (2021), published in Nature Communications
  • "A guide to naming human non-coding RNA genes" (2020), published in The EMBO Journal
  • "The UCSC SARS-CoV-2 Genome Browser" (2020), published in Nature Genetics

Todd M. Lowe frequently collaborates with several researchers, notably Patricia P. Chan, Aidan C. Manning, Blake Sweeney, Anton I. Petrov, and Carlos Eduardo Ribas. These collaborations are evident across multiple publications.

Their research has appeared in a variety of scientific venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Advanced Science
  • Cell Reports
  • Nature Communications

In 2003, Todd M. Lowe received the award of Fellow of the Alfred P. Sloan Foundation. The award recognizes contributions to scientific research in their fields of study.

Best Publications

  • Initial sequencing and analysis of the human genome.

    Eric S. Lander;Lauren M. Linton;Bruce Birren;Chad Nusbaum

  • tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence.

    Todd M. Lowe;Sean R. Eddy

  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

    Ewan Birney;John A. Stamatoyannopoulos;Anindya Dutta;Roderic Guigó

  • tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes

    Todd M. Lowe;Patricia P. Chan

  • The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs

    Peter Schattner;Angela N. Brooks;Todd M. Lowe

  • The genome sequence of Schizosaccharomyces pombe

    V. Wood;R. Gwilliam;M.A. Rajandream;M. Lyne

  • dbEST — database for “expressed sequence tags”

    Mark S. Boguski;Todd M.J. Lowe;Carolyn M. Tolstoshev

  • tRNAscan-SE: Searching for tRNA Genes in Genomic Sequences.

    Patricia P Chan;Todd M Lowe

  • tRNAscan-SE 2.0: improved detection and functional classification of transfer RNA genes.

    Patricia P Chan;Brian Y Lin;Allysia J Mak;Todd M Lowe

  • GtRNAdb: a database of transfer RNA genes detected in genomic sequence

    Patricia P. Chan;Todd M. Lowe

  • Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaea

    C.B. Walker;J.R. De la Torre;M.G. Klotz;H. Urakawa

  • Genome sequence of Halobacterium species NRC-1

    Wailap Victor Ng;Wailap Victor Ng;Sean P. Kennedy;Gregory G. Mahairas;Gregory G. Mahairas;Brian Berquist

  • GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes.

    Patricia P. Chan;Todd M. Lowe

  • General concepts for PCR primer design.

    C W Dieffenbach;T M Lowe;G S Dveksler

  • A computational screen for methylation guide snoRNAs in yeast.

    Todd M. Lowe;Sean R. Eddy

  • ARM-seq: AlkB-facilitated RNA methylation sequencing reveals a complex landscape of modified tRNA fragments

    Aaron E Cozen;Erin Quartley;Andrew D Holmes;Eva Hrabeta-Robinson

  • Homologs of Small Nucleolar RNAs in Archaea

    Arina D. Omer;Todd M. Lowe;Anthony G. Russell;Holger Ebhardt

  • A computer program for selection of oligonucleotide primers for polymerase chain reactions

    Todd Lowe;John Sharefkin;Shi Qi Yang;Carl W. Dieffenbach

  • FragSeq: transcriptome-wide RNA structure probing using high-throughput sequencing

    Jason G Underwood;Andrew V Uzilov;Sol Katzman;Courtney S Onodera

  • The Complete Genome Sequence of Haloferax volcanii DS2, a Model Archaeon

    Amber L. Hartman;Amber L. Hartman;Amber L. Hartman;Cédric Norais;Cédric Norais;Jonathan H. Badger;Stéphane Delmas

Frequent Co-Authors

Alex Bateman
Alex Bateman European Bioinformatics Institute
Elspeth A. Bruford
Elspeth A. Bruford University of Cambridge
Peter F. Stadler
Peter F. Stadler Leipzig University
Robert D. Finn
Robert D. Finn European Bioinformatics Institute
Sam Griffiths-Jones
Sam Griffiths-Jones University of Manchester
Robin R. Gutell
Robin R. Gutell The University of Texas at Austin
David Haussler
David Haussler University of California, Santa Cruz
Sean R. Eddy
Sean R. Eddy Harvard University
Hans Lehrach
Hans Lehrach Max Planck Society

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