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Genetics

D-Index
48
Citations
13922
World Ranking
4028
National Ranking
271

Overview

Thomas Lahaye is a researcher affiliated with the University of Tübingen in Germany. Their academic work predominantly lies within the fields of Agricultural and Biological Sciences as well as Biochemistry, Genetics and Molecular Biology.

The scientific focus of Thomas Lahaye is reflected in their extensive publication record that includes key subfields such as Plant Science and Molecular Biology. Additional research areas encompass Nutrition and Dietetics, Food Science, and Rheumatology. Their specific research topics cover Plant-Microbe Interactions and Immunity, Plant Pathogenic Bacteria Studies, Plant tissue culture and regeneration, CRISPR and Genetic Engineering, Plant Parasitism and Resistance, Photosynthetic Processes and Mechanisms, and Phytase and its Applications.

Thomas Lahaye has contributed to notable journals with several frequently published venues, including bioRxiv (Cold Spring Harbor Laboratory) where they have 5 publications. Other venues featuring their work include Nature Plants with 3 publications, Plant Biotechnology Journal and PLoS Pathogens with 2 publications each, and Cell with 1 publication.

Their recent papers feature a range of topics and publication years:

  • Co-incidence of Damage and Microbial Patterns Controls Localized Immune Responses in Roots, 2020, Cell
  • Targeted introduction of heritable point mutations into the plant mitochondrial genome, 2022, Nature Plants
  • Host-associated microbe PCR (hamPCR) enables convenient measurement of both microbial load and community composition, 2021, eLife
  • Targeted knockout of a conserved plant mitochondrial gene by genome editing, 2023, Nature Plants
  • The phytase RipBL1 enables the assignment of a specific inositol phosphate isomer as a structural component of human kidney stones, 2023, RSC Chemical Biology

Throughout their career, Thomas Lahaye has collaborated frequently with other researchers. Notable coauthors include:

  • Annett Strauß
  • Robert Morbitzer
  • Gabriel Schaaf
  • Dousheng Wu
  • Danalyn R. Holmes

Best Publications

  • Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors

    Jens Boch;Heidi Scholze;Sebastian Schornack;Angelika Landgraf

  • A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity

    Claudio Mussolino;Robert Morbitzer;Fabienne Lütge;Nadine Dannemann

  • Plant pathogen recognition mediated by promoter activation of the pepper Bs3 resistance gene.

    Patrick Römer;Simone Hahn;Tina Jordan;Tina Strauß

  • TAL effectors: finding plant genes for disease and defense.

    Adam J Bogdanove;Sebastian Schornack;Thomas Lahaye

  • A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans.

    Ken Shirasu;Thomas Lahaye;Man Wah Tan;Fasong Zhou

  • Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors

    Robert Morbitzer;Patrick Römer;Jens Boch;Thomas Lahaye

  • A contiguous 66-kb barley DNA sequence provides evidence for reversible genome expansion.

    Ken Shirasu;Alan H. Schulman;Thomas Lahaye;Paul Schulze-Lefert

  • Assembly of custom TALE-type DNA binding domains by modular cloning

    Robert Morbitzer;Janett Elsaesser;Jens Hausner;Thomas Lahaye

  • Modular dna-binding domains and methods of use

    Ulla Bonas;Jens Boch;Sebastian Schornack;Thomas Lahaye

  • Xanthomonas axonopodis virulence is promoted by a transcription activator-like effector-mediated induction of a SWEET sugar transporter in cassava.

    Megan Cohn;Rebecca S. Bart;Mikel Shybut;Douglas Dahlbeck

  • Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers

    Sebastian Bultmann;Robert Morbitzer;Christine S. Schmidt;Katharina Thanisch

  • The tomato resistance protein Bs4 is a predicted non-nuclear TIR-NB-LRR protein that mediates defense responses to severely truncated derivatives of AvrBs4 and overexpressed AvrBs3.

    Sebastian Schornack;Agim Ballvora;Doreen Gürlebeck;Jack Peart

  • Plant disease resistance triggered by pathogen-derived molecules: refined models of specific recognition

    Ulla Bonas;Thomas Lahaye

  • Promoter elements of rice susceptibility genes are bound and activated by specific TAL effectors from the bacterial blight pathogen, Xanthomonas oryzae pv. oryzae.

    Patrick Römer;Patrick Römer;Sabine Recht;Sabine Recht;Tina Strauß;Tina Strauß;Janett Elsaesser;Janett Elsaesser

  • Gene-for-gene-mediated recognition of nuclear-targeted AvrBs3-like bacterial effector proteins.

    Sebastian Schornack;Annett Meyer;Patrick Römer;Tina Jordan

  • TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

    Claudio Mussolino;Jamal Alzubi;Eli J. Fine;Robert Morbitzer

  • A single plant resistance gene promoter engineered to recognize multiple TAL effectors from disparate pathogens

    Patrick Römer;Sabine Recht;Thomas Lahaye

  • Quantitative analysis of TALE–DNA interactions suggests polarity effects

    Joshua F. Meckler;Mital S. Bhakta;Moon-Soo Kim;Robert Ovadia

  • Co-incidence of Damage and Microbial Patterns Controls Localized Immune Responses in Roots.

    Feng Zhou;Aurélia Emonet;Valérie Dénervaud Tendon;Peter Marhavy

  • TAL effectors--pathogen strategies and plant resistance engineering.

    Jens Boch;Ulla Bonas;Thomas Lahaye

Frequent Co-Authors

Ulla Bonas
Ulla Bonas Martin Luther University Halle-Wittenberg
Sebastian Schornack
Sebastian Schornack University of Cambridge
Jens Boch
Jens Boch University of Hannover
Jeffrey B. Jones
Jeffrey B. Jones University of Florida
Brian J. Staskawicz
Brian J. Staskawicz University of California, Berkeley
Toni Cathomen
Toni Cathomen University of Freiburg
Martin W. Ganal
Martin W. Ganal TraitGenetics GmbH
Gerald V. Minsavage
Gerald V. Minsavage University of Florida
Paul Schulze-Lefert
Paul Schulze-Lefert Max Planck Society
Robert E. Stall
Robert E. Stall University of Florida

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