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Thomas J. Sayers

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
8806
World Ranking
16779
National Ranking
6925

Thomas J. Sayers publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Thomas J. Sayers sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 145 publications — 24th percentile

24% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Thomas J. Sayers D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Thomas J. Sayers sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 52 D-Index — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Thomas J. Sayers is affiliated with Leidos in the United States and has contributed to research primarily in the fields of biochemistry, genetics and molecular biology, immunology and microbiology, and medicine. Their work spans several subfields including molecular biology, immunology, oncology, and complementary and alternative medicine.

The main topics of study in their research include cell death mechanisms and regulation, immunotherapy and immune responses, RNA interference and gene delivery, phytochemicals and medicinal plants, PARP inhibition in cancer therapy, CAR-T cell therapy research, and immune cell function and interaction.

Sayers has published research in multiple scientific venues. Frequent publication platforms for their work are:

  • Cancer Research
  • Journal of Natural Products
  • Frontiers in Immunology

Selected publications by Thomas J. Sayers include:

  • Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins, 2021, Cancer Research
  • Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma, 2021, Journal of Natural Products
  • CD8+ T-NK cell crosstalk establishes preemptive immunosurveillance to eliminate antigen-escape tumors, 2025, Frontiers in Immunology

The scientist has worked with several frequent co-authors, including:

  • Poonam Tewary
  • Alan D. Brooks
  • Ya-Ming Xu
  • E. M. Kithsiri Wijeratne
  • Maria Teresa P. de Aquino

Best Publications

  • Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis.

    D. D. Taub;T. J. Sayers;C. R. D. Carter;J. R. Ortaldo

  • Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes

    Karin A Sedelies;Thomas J Sayers;Kirsten M Edwards;Weisan Chen

  • Identification of Human Neutrophil-derived Cathepsin G and Azurocidin/CAP37 as Chemoattractants for Mononuclear Cells and Neutrophils

    Oleg Chertov;Hirotsugu Ueda;Luo Ling Xu;Kenji Tani

  • Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib

    Kai Sun;Lisbeth A. Welniak;Angela Panoskaltsis-Mortari;Matthew J. O'Shaughnessy

  • Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

    Ancy D. Nalli;Lauren E. Brown;Cheryl L. Thomas;Thomas J. Sayers

  • Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy

    Kazuyoshi Takeda;Noriko Yamaguchi;Hisaya Akiba;Yuko Kojima

  • Targeting the extrinsic apoptosis signaling pathway for cancer therapy.

    Thomas J. Sayers

  • The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.

    Thomas J. Sayers;Alan D. Brooks;Crystal Y. Koh;Weihong Ma

  • The Trophic Action of IL-7 on Pro-T Cells: Inhibition of Apoptosis of Pro-T1, -T2, and -T3 Cells Correlates with Bcl-2 and Bax Levels and Is Independent of Fas and p53 Pathways

    Kyungjae Kim;Chong-kil Lee;Thomas J. Sayers;Kathrin Muegge

  • Unlocking the secrets of cytotoxic granule proteins

    Mark J. Smyth;Janice M. Kelly;Vivien R. Sutton;Joanne E. Davis

  • NKG2D Recognition and Perforin Effector Function Mediate Effective Cytokine Immunotherapy of Cancer

    Mark J. Smyth;Jeremy Swann;Janice M. Kelly;Erika Cretney

  • NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

    Erik Ames;Robert J. Canter;Steven K. Grossenbacher;Stephanie Mac

  • New flow cytometric assays for monitoring cell-mediated cytotoxicity.

    Liubov Zaritskaya;Michael R Shurin;Thomas J Sayers;Anatoli M Malyguine

  • Tumor-specific CTL kill murine renal cancer cells using both perforin and Fas ligand-mediated lysis in vitro, but cause tumor regression in vivo in the absence of perforin.

    Naoko Seki;Alan D. Brooks;Clive R. D. Carter;Timothy C. Back

  • Effect of cytokines on polymorphonuclear neutrophil infiltration in the mouse. Prostaglandin- and leukotriene-independent induction of infiltration by IL-1 and tumor necrosis factor.

    T J Sayers;T A Wiltrout;C A Bull;A C Denn rd

  • Synthesis of potential anticancer agents.

    Charles E. Williamson;Thomas J. Sayers;Arnold M. Seligman;Benjamin. Witten

  • Sensitization of Tumor Cells to NK Cell-Mediated Killing by Proteasome Inhibition

    William H.D. Hallett;Erik Ames;Milad Motarjemi;Isabel Barao

  • Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity

    Kai Sun;Danice E. C. Wilkins;Miriam R. Anver;Thomas J. Sayers

  • The Granzyme B ELISPOT assay: an alternative to the 51Cr-release assay for monitoring cell-mediated cytotoxicity.

    Kimberly A Shafer-Weaver;Thomas J Sayers;Susan Strobl;E G Derby

  • Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer.

    Naoko Seki;Yoshihiro Hayakawa;Alan D. Brooks;John Wine

Frequent Co-Authors

William J. Murphy
William J. Murphy Texas A&M University
Robert H. Wiltrout
Robert H. Wiltrout National Institutes of Health
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Jon M. Wigginton
Jon M. Wigginton Bristol-Myers Squibb (Germany)
Hideo Yagita
Hideo Yagita Juntendo University
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
A. A. Leslie Gunatilaka
A. A. Leslie Gunatilaka University of Arizona
James B. McMahon
James B. McMahon National Institutes of Health
John R. Ortaldo
John R. Ortaldo National Institutes of Health
Dan L. Longo
Dan L. Longo Harvard University

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Best Scientists Citing Thomas J. Sayers

Mark J. Smyth

Mark J. Smyth

QIMR Berghofer Medical Research Institute

Publications: 107

William J. Murphy

William J. Murphy

Texas A&M University

Publications: 72

Hideo Yagita

Hideo Yagita

Juntendo University

Publications: 46

Joseph A. Trapani

Joseph A. Trapani

Peter MacCallum Cancer Centre

Publications: 43

Bruce R. Blazar

Bruce R. Blazar

University of Minnesota

Publications: 36

Kazuyoshi Takeda

Kazuyoshi Takeda

Juntendo University

Publications: 35

Robert H. Wiltrout

Robert H. Wiltrout

National Institutes of Health

Publications: 26

Yoshihiro Hayakawa

Yoshihiro Hayakawa

Aichi Institute of Technology

Publications: 23

Henning Walczak

Henning Walczak

University College London

Publications: 21

Simone Fulda

Simone Fulda

Goethe University Frankfurt

Publications: 21

Scott K. Durum

Scott K. Durum

National Institutes of Health

Publications: 21

Oliver Soehnlein

Oliver Soehnlein

University of Münster

Publications: 18

Thomas P. Loughran

Thomas P. Loughran

University of Virginia

Publications: 18

Kebin Liu

Kebin Liu

Augusta University

Publications: 18

Dennis D. Taub

Dennis D. Taub

George Washington University

Publications: 17

Ko Okumura

Ko Okumura

Juntendo University

Publications: 17

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